Biochemistry of the Entner-Doudoroff Pathway

The video tutorial explains the Entner-Doudoroff pathway, an alternative sugar metabolism route in some bacteria. It contrasts this pathway with glycolysis, highlighting the production of NADPH and ATP. The tutorial details the oxidative pentose phosphate pathway and the conversion of glucose to pyruvate, emphasizing the differences in energy yield and cofactor production compared to glycolysis.

Which pathway is the default for sugar metabolism in most eukaryotic organisms?

• Citric acid cycle

• Glycolysis

• Entner-Doudoroff pathway

• Pentose phosphate pathway

What is the primary function of the oxidative pentose phosphate pathway in the Entner-Doudoroff pathway?

• To produce ATP

• To generate NADPH

• To synthesize glucose

• To create pyruvate

Which enzyme is responsible for splitting KD, PG into pyruvate and glyceraldehyde 3-phosphate?

• KDG aldolase

• Phosphoglycerate kinase

• Enolase

• Hexokinase

In the Entner-Doudoroff pathway, what is the fate of glyceraldehyde 3-phosphate?

• It enters the last half of glycolysis

• It is oxidized to form NADPH

• It is converted into glucose

• It is used to synthesize fatty acids

How does the ATP yield of the Entner-Doudoroff pathway compare to glycolysis?

• It produces the same amount of ATP

• It produces more ATP

• It produces less ATP

• It does not produce ATP

What is a unique product of the Entner-Doudoroff pathway that is not produced in glycolysis?

• ATP

• FADH2

• NADPH

• NADH

What is the role of NADPH in cellular metabolism?

• It is used in the electron transport chain

• It is involved in biosynthetic reactions

• It is used to generate ATP directly

• It is a byproduct of glycolysis