Malate-Aspartate Shuttle

Malate-Aspartate Shuttle

Assessment

Interactive Video

•

Health Sciences, Biology

•

University - Vocational training

•

Practice Problem

•

Hard

Created by

Wayground Content

FREE Resource

The video explains the malate aspartate shuttle, a crucial mechanism for transporting NADH from glycolysis into the mitochondria for ATP production. It details the impermeability of the mitochondrial membrane to NADH and the role of antiporters in the shuttle process. The video covers the enzymatic reactions involved, including the conversion of oxaloacetate to malate and back, and the role of concentration gradients. It also discusses the cycle of aspartate and glutamate and the shuttle's application in gluconeogenesis.

Read more

10 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Why is the malate aspartate shuttle necessary for NADH transport into mitochondria?

The mitochondrial membrane is impermeable to NADH.

NADH is too large to pass through the membrane.

NADH is unstable outside the cytosol.

NADH is converted to ATP outside the mitochondria.

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the role of antiporters in the malate aspartate shuttle?

They convert NADH to ATP.

They stabilize the mitochondrial membrane.

They transport NADH directly.

They facilitate the exchange of molecules across the membrane.

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which cells primarily utilize the malate aspartate shuttle?

Skin and bone cells

Red blood cells and platelets

Cardiac muscle and liver cells

Neurons and muscle cells

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What role does oxaloacetate play in the malate aspartate shuttle?

It stabilizes the mitochondrial membrane.

It directly enters the mitochondria.

It is converted into ATP.

It acts as a carrier for energy within NADH.

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme is responsible for converting malate back to oxaloacetate in the mitochondria?

Pyruvate carboxylase

Aspartate aminotransferase

Mitochondrial malate dehydrogenase

Cytosolic malate dehydrogenase

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the function of glutamate in the malate aspartate shuttle?

It acts as a carrier for NADH.

It donates an amino group to oxaloacetate.

It stabilizes the mitochondrial membrane.

It is converted into ATP.

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

How is aspartate transported out of the mitochondria?

Through a malate transporter

Via the glutamate aspartate antiporter

Directly through the mitochondrial membrane

By converting into oxaloacetate first

Access all questions and much more by creating a free account

Create resources

Host any resource

Get auto-graded reports

Google

Continue with Google

Email

Continue with Email

Classlink

Continue with Classlink

Clever

Continue with Clever

or continue with

Microsoft

Microsoft

Apple

Apple

Others

Others

Already have an account?