Catabolism of Aminomuconate Semialdehyde to Glutaryl-S-CoA

The video explores the degradation of tryptophan to glutarate, focusing on glucogenic and ketogenic pathways. It details the decarboxylation and dehydrogenation processes, highlighting the role of various enzymes and complexes. The video concludes with a preview of the next topic on glutaryl CoA catabolism.

What is the significance of the glucogenic part of the tryptophan degradation pathway?

• It results in the production of amino acids.

• It generates fatty acids.

• It leads to the formation of glucose.

• It produces ketone bodies.

Which group is removed during the decarboxylation of 2 amino, three carboxy mucronate, 6 semi aldehyde?

• The hydroxyl group

• The amino group

• The three carboxy group

• The aldehyde group

What is the role of aldehyde dehydrogenase in the conversion process?

• It removes an amino group.

• It adds a phosphate group.

• It converts an aldehyde to a carboxylate.

• It adds a hydroxyl group.

What is the significance of the enzyme not yet characterized in the pathway?

• It produces NADH.

• It converts 2 amino mucronate to Alpha keto adipate.

• It generates ATP.

• It breaks down glucose.

Which complex is mechanistically similar to the Alpha keto adipate dehydrogenase complex?

• Malate dehydrogenase complex

• Citrate synthase complex

• Lactate dehydrogenase complex

• Pyruvate dehydrogenase complex

What is the final product of the Alpha keto adipate dehydrogenase complex?

• Lactate

• Pyruvate

• Glutaryl Co A

• Acetyl Co A

How is NADH utilized in the pathway discussed?

• It is stored in the liver.

• It is used to synthesize fatty acids.

• It powers the mitochondrial respiratory chain.

• It is converted to ATP directly.