020 Facilitation

Leslie Samuel explains the process of facilitation in neurons, focusing on how it leads to a prolonged and stronger response in the postsynaptic cell. The video covers the role of action potentials, calcium channels, and neurotransmitter release. It also details the involvement of serotonin, G proteins, adenylate cyclase, and protein kinase C in modulating potassium channels, ultimately enhancing neurotransmitter release and signal strength.

What happens when an action potential reaches the axon terminal?

• Voltage gated sodium channels open.

• Voltage gated calcium channels open.

• Potassium ions rush into the cell.

• Neurotransmitters are absorbed.

Which neurotransmitter is released by the facilitatory neuron during facilitation?

• GABA

• Acetylcholine

• Serotonin

• Dopamine

What is the role of adenylate cyclase in the facilitation process?

• It deactivates G proteins.

• It releases neurotransmitters.

• It opens voltage gated sodium channels.

• It converts ATP to cyclic AMP.

How does protein kinase C affect the potassium channels during facilitation?

• It opens them wider.

• It has no effect.

• It makes them more permeable.

• It closes them.

What is the overall effect of facilitation on the postsynaptic cell?

• A delayed signal.

• A stronger and longer signal.

• No change in signal strength.

• A weaker and shorter signal.