Glycolysis and Gluconeogenesis Regulation 2

The video discusses the regulation of glycolysis and gluconeogenesis, focusing on the allosteric effects of fructose 2,6-bisphosphate. It explains how this molecule activates glycolysis by stimulating PFK-1 and inhibits gluconeogenesis by reducing the affinity of fructose bisphosphatase-1 for its substrate. The video emphasizes the importance of these regulatory mechanisms in metabolic pathways.

What is the primary role of fructose 2,6-bisphosphate in glycolysis?

• It activates PFK-1.

• It inhibits PFK-1.

• It converts glucose to fructose.

• It deactivates ATP.

Which enzyme is responsible for converting fructose 1,6-bisphosphate to fructose 6-phosphate?

• Hexokinase

• PFK-1

• Fructose bisphosphatase-1

• Glucose-6-phosphatase

How does fructose 2,6-bisphosphate affect fructose bisphosphatase-1?

• It decreases its affinity for fructose 1,6-bisphosphate.

• It has no effect on it.

• It increases its affinity for fructose 1,6-bisphosphate.

• It converts it to an inactive form.

What is the effect of fructose 2,6-bisphosphate on gluconeogenesis?

• It activates gluconeogenesis.

• It inhibits gluconeogenesis.

• It has no effect on gluconeogenesis.

• It converts gluconeogenesis to glycolysis.

Which enzyme is activated by fructose 2,6-bisphosphate to stimulate glycolysis?

• Glucose-6-phosphatase

• PFK-1

• Hexokinase

• Fructose bisphosphatase-1