Galactose Absorption and Metabolism | Leloir Pathway and Galactosemia

The video tutorial explains galactose, a hexose sugar, and its dietary sources like milk and fruits. It details the absorption process of galactose in the body, involving transporters like SGLT1. The metabolism of galactose through the Loire pathway is discussed, highlighting the conversion to glucose 1 phosphate. The video also covers galactosemia, a condition caused by enzyme deficiencies, leading to high blood galactose levels.

What is galactose primarily found in?

• Meat and poultry

• Human and bovine milk

• Nuts and seeds

• Fish and seafood

Which transporter is responsible for moving galactose into intestinal cells?

• GLUT 4

• GLUT 5

• GLUT 2

• SGLT 1

How is beta D galactose converted to alpha D galactose?

• By the enzyme phosphoglucomutase

• By the enzyme lactase

• By the enzyme galactose mutarotation

• By the enzyme galactose kinase

What is the final product of galactose metabolism that enters glycolysis?

• Glucose 6 phosphate

• Lactose

• Glucose 1 phosphate

• Pyruvate

What is the most common enzyme deficiency leading to classic galactosemia?

• UDP galactose epimerase

• Galactose kinase

• Galactose 1 phosphate uridyl transferase

• Hexokinase

Which enzyme deficiency is associated with the development of cataracts?

• Galactose 1 phosphate uridyl transferase

• Galactose kinase

• UDP galactose epimerase

• Phosphoglucomutase

What condition results from a deficiency in enzymes involved in galactose metabolism?

• Lactose intolerance

• Fructose malabsorption

• Galactosemia

• Diabetes