Muscle Physiology: Myosin Mechanism

The video tutorial explains the mechanism of myosin ATPase, focusing on its role in muscle contraction. It covers the binding of ATP to myosin, leading to crossbridge detachment from actin. The hydrolysis of ATP activates the myosin head, allowing it to reattach to actin and perform a power stroke, resulting in sarcomere contraction. The process involves the formation and dissociation of metaphosphate and orthophosphate, ultimately leading to the release of ADP and the completion of the cycle.

What is metaphosphate and how is it formed during the cycle?

How does the conformational change in myosin contribute to muscle contraction?

What is the final outcome of the myosin-actin cycle?