Anatomy - Mechanisms of Smooth Muscle Contraction

The video explains the unique mechanisms of smooth muscle contraction, contrasting it with skeletal and cardiac muscles. It details three activation methods: stretch channels, catecholamines, and antidiuretic hormone, each leading to different second messengers. These messengers trigger calcium release from the sarcoplasmic reticulum, which binds to calmodulin, activating myosin light chain kinase. This process results in phosphorylation of myosin, enabling cross-bridge formation with actin, leading to contraction.

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