Coproporphyrinogen Oxidase: Physiology, Biochemistry, and Organic Mechanism

The video explores the physiology, biochemistry, and mechanism of copro porphyrinogen oxidase, an enzyme involved in heme synthesis. It discusses the enzyme's systematic name, subcellular location, and recent discoveries about its mechanism. The video also covers the genetic mutation leading to enzyme deficiency, known as porphyria, and compares the enzyme's oxidative decarboxylation process with other enzymes. The video concludes with a brief mention of future topics related to protoporphyrinogen and heme B synthesis.

What is the systematic name of the enzyme discussed in the video?

Describe the subcellular compartmentalization of the enzyme mentioned.

What happens to copro porphyrinogen 3 during the reaction?

Discuss the importance of the gene cpox in relation to the enzyme.

What are the symptoms associated with a deficiency of the enzyme discussed?

Explain the significance of the term 'oxidative decarboxylation' in the context of this enzyme.

What role does molecular oxygen play in the reactions discussed?

What is the final product of the reaction catalyzed by copro porphyrinogen oxidase?

How does the mechanism of copro porphyrinogen oxidase differ from that of copro porphyrinogen dehydrogenase?

What are the steps involved in the transformation of protoporphyrinogen to protoporphyrin?