Endocannabinoids [Part 1] | Biosynthesis of Anandamide & 2-AG

The video tutorial by Kevin Tolkoff introduces endocannabinoids, focusing on their biosynthesis. It explains the synthesis of two major endocannabinoids, anandamide and 2-AG, from phospholipids. The process involves enzymes like NaCl transferase, phospholipase D, and phospholipase C. The tutorial highlights the committed step in endocannabinoid synthesis and the role of calcium in activating NaCl transferase. The video sets the stage for understanding the mechanism of action of endocannabinoids in future videos.

What are endocannabinoids and how are they produced in the body?

Describe the biosynthesis process of endocannabinoids.

Explain the significance of arachidonic acid in the formation of endocannabinoids.

How does phospholipase D contribute to the production of anandamide?

What is the function of diacylglycerol lipase in the context of endocannabinoid synthesis?

What are the two major endocannabinoids mentioned in the video?

What role does NaCl transferase play in endocannabinoid synthesis?