Dopachrome Tautomerase: Physiology, Biochemistry, and Mechanism

The video explores the mechanism and physiology of the enzyme dopethrone tautomerase, also known as DOPA Chrome isomerase. It discusses the synthesis of melanin in melanocytes, focusing on the role of tyrosinase and DOPA Chrome tautomerase in converting DOPA to DOPA Chrome and further to dihydroxy indole carboxylic acid. The video explains the enzyme's structure, function, and the catalytic role of zinc cations and water molecules in the active site. The spontaneous and enzymatic pathways of the reaction are also covered.

Discuss the importance of the melanosome in the synthesis of melanin.

What is the relationship between DOPA Chrome and dihydroxy indole carboxylic acid?

What is the end product of the reaction catalyzed by DOPA Chrome tautomerase?

How does the presence of metal cations affect the reaction sequence in melanin synthesis?