Acetyl-S-CoA Synthetase: Physiology, Biochemistry, and Mechanism

The video explains the conversion of acetate to acetyl CoA, highlighting the role of acetyl CoA synthetase. It discusses the toxic nature of acetate, the enzyme's mechanism, and the thermodynamic aspects of the reaction. The video also covers the biological significance of acetyl CoA in the TCA cycle and its role in biosynthesis, emphasizing the energy release and the importance of removing toxic acetate.

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