Glutaminase Catabolism of Glutamine

The video explains the mechanism of glutaminase, an enzyme that reverses the reaction of glutamine synthetase by converting glutamine back to glutamate. It details the steps involved in the enzyme's mechanism, including nucleophilic attack and hydrolysis, and highlights the enzyme's importance in energy production and the urea cycle. The video also discusses the role of glutaminase in the liver's mitochondria, where it helps catabolize glutamine for energy and facilitates ammonia excretion through the urea cycle.

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