Superoxides and Superoxide Dismutase: Physiology, Biochemistry, and Inorganic Mechanism

Superoxides and Superoxide Dismutase: Physiology, Biochemistry, and Inorganic Mechanism

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Science, Chemistry, Biology

University

Hard

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This video explores the production and destruction of superoxide, focusing on its biochemistry and physiology. It discusses various enzymes that produce superoxide, such as NADPH oxidase and cytochrome P-450, and the role of superoxide dismutase in detoxifying superoxide. The video also examines the impact of superoxide on the TCA cycle, particularly its effect on aconitase. Detailed mechanisms of superoxide dismutase are explained, highlighting the role of metal ions like zinc and copper. The video concludes with a discussion on hydrogen peroxide and nitric oxide, emphasizing the dangers of peroxynitrite formation.

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OPEN ENDED QUESTION

3 mins • 1 pt

What new insight or understanding did you gain from this video?

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