APES 8.12-8.13 Video

What does LD50 stand for?

• Lethal Dose 50

• Limited Dosage

• Lowest Detectable

• Lasting Dosage

Which of the following is NOT a common unit for expressing LD50 data?

• Milligrams per kilogram of body mass - mg/kg

• PPM- Parts Per Million

• Mass per Volume - kg/L

• Seconds/Dose- s/dose

 In a dose-response study, what is typically plotted on the x-axis?

• % moratality

• Time

• Dose Concentration

• Body Mass

What is the threshold in a dose-response curve?

• The highest concentration tested

• The lowest detectable level where a response is seen

• The concentration that kills 100% of organisms

• The midpoint of the curve

Why do dose-response curves typically have an S-shape?

• It's a requirement for scientific studies

• The equipment used always produces this shape

• Different organisms have different tolerance levels

•  It represents the alphabet "S" for "Science"

What does ED50 stand for?

• Effective Dose 50

• Elevated Death 50

• Extreme Danger 50

• Environmental Decline 50

When determining acceptable levels of pollutants for humans based on animal studies, what factor is typically applied?

•  The animal dose is multiplied by 1000

• The animal dose is divided by 1000

• The animal dose is used directly

• The animal dose is squared

What is a limitation of acute dose-response studies?

• They're too expensive to conduct

• They don't show long-term developmental issues

• They can only be done on small animals

• They always overestimate toxicity