Atheroma formation

What is the initial event in the development of atherosclerosis?

• Cholesterol accumulation

• Damage to the artery wall endothelium

• Formation of foam cells

• Increased blood pressure

What is the role of monocytes in the development of atheroma?

• They form a hard plaque.

• They transport cholesterol out of the artery wall.

• They transform into macrophages and digest cholesterol.

• They cause the endothelium to rupture.

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What substances accumulate within the atheroma to form a hard plaque, leading to reduced artery wall elasticity and increased blood pressure?

• Red blood cells and platelets

• Fibrin and thrombin

• Calcium salts and fibrous tissue

• Monocytes and macrophages

What is the immediate consequence when the endothelium ruptures over a hard plaque?

• Blood pressure decreases.

• Cholesterol is reabsorbed.

• Collagen is exposed, leading to platelet activation.

• Foam cells are formed.