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DNA Structure & Replication (H Bio)

Total questions: 35

Worksheet time: 31mins

Name
Class
Date
1.

In DNA replication, the lagging strand will form off of the parent strand that ENDS with

a)

5'

b)

3'

2.

Which enzyme makes sure the bases pair up correctly during DNA replication?

a)

Primase

b)

Helicase

c)

DNA polymerase

d)

DNA ligase

3.

Which strand is synthesized continuously during DNA Replication?

a)

Leading Strand

b)

Lagging Strand

4.

Which of the following enzymes are NOT involved in DNA replication?

a)

RNA polymerase

b)

Primase

c)

DNA ligase

d)

DNA polymerase

5.

What enzyme is responsible for laying down the RNA primers during DNA Replication?

a)

DNA Helicase

b)

Primase

c)

DNA Ligase

d)

RNA polymerase

6.

The bonds that hold the two strands of DNA together are

a)

strong hydrogen bonds.

b)

weak covalent bonds.

c)

strong covalent bonds.

d)

weak hydrogen bonds.

7.

The leading strand is built__________ the replication fork, and the lagging strand is built ___________ the replication fork.

a)

towards, towards

b)

away from, away from

c)

away from, towards

d)

towards, away from

8.

Small segments of DNA made on the lagging strand are called:

a)

Okazaki Fragments

b)

DNA primers

c)

RNA primers

d)

Telomeres

9.
What is the complement to the DNA strand below:
5'-ATGCCAT-3'
a)
5'-TACGGTA-3'
b)
3'-TACGGTA-5'
c)
3'-ATGGCAT-5'
d)
5'-ATGGCAT-3'
10.

Most potential mistakes made during DNA replication are corrected by

a)

helicase

b)

DNA polymerase

c)

primase

d)

DNA ligase

11.
For what reason does DNA copy itself?
a)
to replace worn out DNA
b)
so cells can divide
c)
to export DNA to other parts of the body
d)
more DNA is better
12.

The enzyme that unzips the DNA to prepare for replication ("The Unzipper")

a)

Helicase

b)

DNA ligase

c)

DNA polymerase

d)

RNA polymerase

13.
What strand is copied backwards?
a)
Leading
b)
Lagging
14.
Name this structure
a)
double helix
b)
nucelotide
c)
amino acid
d)
protein
15.
Which 2 molecules forms the sides (backbone) of the DNA ladder?
a)
ribose (sugar) and nitrogen bases
b)
ribose (sugar) and phosphate
c)
deoxyribose (sugar) and nitrogen bases
d)
deoxyribose (sugar) and phosphate
16.
What determines the code, or information, of a DNA molecule?
a)
the shape (structure) of the nitrogen bases
b)
the order (sequence) of the nitrogen bases
c)
the color of the nitrogen bases
d)
the frequency (number) of nitrogen bases
17.
In a molecule of double-stranded DNA, the amount of Adenine present is always equal to the amount of
a)
cytosine
b)
guanine
c)
thymine
d)
uracil
18.
If Chargaff found that a sample of DNA has 20% ADENINE, how much GUANINE would he have determined to be there?
a)
30%
b)
20%
c)
80%
d)
60%
19.
Adenine forms a ______ bond with ________.
a)
double hydrogen; guanine
b)
double hydrogen; thymine
c)
triple hydrogen; guanine
d)
triple hydrogen; thymine
20.

On the diagram below, which number is the Okazaki fragment?

a)

3

b)

4

c)

6

d)

8

21.

On the diagram below, which number represents the leading strand?

a)

1

b)

2

c)

3

d)

8

22.

On the diagram below, which number is the RNA primer?

a)

3

b)

4

c)

6

d)

8

23.

On the diagram below, which number is helicase?

a)

3

b)

4

c)

5

d)

6

24.

TRUE / FALSE. Only the lagging strand contains primers.

a)

TRUE

b)

FALSE

25.

Which enzyme is responsible for linking the nucleotides together?

a)

DNA helicase

b)

DNA ligase

c)

DNA polymerase

d)

Primase

26.

DNA replication results in

a)

2 completely new DNA molecules

b)

2 DNA molecules that each contain a strand of the original

c)

1 new DNA molecule and 1 old

d)

1 new molecule of DNA

27.

The new DNA strand formed after DNA replication is an exact copy of its parent strand

a)

True

b)

False

28.

The picture below shows the steps of DNA replication beginning with step one and ending with step three.


​Because you are reusing the old, or parent, DNA strand DNA replication is said to be

a)

Semi- Conservative

b)

Semi-discontinuous

c)

Continuous

d)

Anti-parallel

29.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

30.

Which letter in the picture below depicts the replication fork in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

31.

The directionality of DNA is said to be ___________, because it is side by side by goes in opposite directions.

a)

leading

b)

parallel

c)

anti-parallel

d)

semi-conservative

32.

In which direction are new nucleotides synthesized on the new strand?

a)

5' to 3' (new nucleotides added to the 3' end)

b)

3' to 5' (new nucleotides added to the 5' end)

c)

3' to 5' (new nucleotides added to the 3' end)

d)

5' to 3' (new nucleotides added to the 5' end)

33.

Why does DNA need to be replicated?

a)

so mRNA can make a copy of it

b)

so each cell that results from cell division has the exact DNA

c)

so that new nitrogen bases can be synthesized

d)

so that new amino acids can be synthesized

34.
Based on the diagram, the enzyme (represented in gray) is most likely...
a)
DNA polymerase
b)
DNA Ligase
c)
Nuclease
d)
Helicase
35.

The term used to describe DNA Replication is

a)

semi-conservative

b)

conservative

c)

anti-parallel

d)

continuous

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