WorksheetsLymphoma and Leukemia ALE
Total questions: 20
Worksheet time: 20mins
True/False: For patients who develop a lymphoma and relapse, one viable treatment option can include an autologous stem cell transplant
True
False
For which of the following type of lymphoma would a patient not initially require treatment?
Diffuse large B-cell lymphoma
Follicular lymphoma
Burkitt's lymphoma
Hodgkin's lymphoma
A patient with a diffuse large B-cell lymphoma is about to be started on CHOP therapy, consisting of cyclophosphamide, doxorubicin, Oncovin (vincristine), and prednisone. After the first couple cycles of CHOP the patient begins to experience some cardiomyopathy. Which medication in CHOP is likely causing this cardiomyopathy?
Cyclophosphamide
Doxorubicin
Vincristine
Prednisone
A patient is about to be started on Obinutuzumab (Gazyva) therapy following treatment failure for a follicular lymphoma. Which of the following is a common adverse effect related to Obinutuzumab therapy?
Viral reactivation
Peripheral neuropathy
Hepatotoxicity
Secondary malignancies
Which of the following best describes the mechanism of action of Ibritumomab tiuxetan (Zevalin)
Targets the CD20 antigen on cells and delivers a radioactive isotope
Targets the CD54 antigen on cells and delivers a diptheria toxin
Targets HER2 over expression on cells and ultimately causes cellular apoptosis
Targets EGFR over expression on cells and ultimately prevents DNA replication
True/False: Hodgkin's lymphoma primarily occurs in younger patients, those between the ages of 10-30.
True
False
A patient with Hodgkin's lymphoma is about to be started on ABVD therapy, consisting of Adriamycin (doxorubicin), Bleomycin, Vinblastine, and Dacarbazine. After the first couple cycles of ABVD the patient begins to experience some darkening of the skin on her arms and torso. Which medication in ABVD is likely causing this change in her skin?
Doxorubicin
Bleomycin
Vinblastine
Dacarbazine
Which of the following agents is contraindicated for patients currently taking bleomycin due to added pulmonary toxicity?
Brentuximab vedotin
Ibritumomab tiuxetan
Obinutuzumab
Rituximab
Which of the following types of lymphoma is cure not normally a goal?
Diffuse large B-cell lymphoma
Follicular lymphoma
Burkitt's lymphoma
MALT lymphoma
True/False: Lymphomas primarily occur due to a malignant transformation of myeloid cells.
True
False
For patient's diagnosed with Acute Myeloid Leukemia (AML), a primary treatment option includes which of the following chemotherapy regimens?
7 + 3 therapy
CHOP therapy
ABVD therapy
Stanford V therapy
Which of the following types of leukemia likes to "hide" from chemotherapy using the reservoir sites of the CNS and the testicles in male patients?
AML
ALL
CML
NHL
For which of the following types of leukemias should a patient begin Philadelphia chromosome targeted therapy for life?
AML
ALL
CML
CLL
For which of the following types of leukemias should a patient not have to be treated for early stage disease?
AML
ALL
CML
CLL
True/False: For patients who have Acute Lymphoblastic Leukemia, following treatment relapse an appropriate therapy option could include an autologous stem-cell transplant.
True
False
For a patient who has progressed to the blast crisis phase of CML, which of the following treatment options would be appropriate at this time?
7 + 3 therapy
ABVD therapy
CHOP therapy
Stanford V therapy
Which of the following adverse effects is commonly associated with tumor lysis syndrome in patients undergoing chemotherapy for leukemias?
Kidney failure
Liver failure
Seizures
Nausea
Which of the following agents can be used in patients with tumors who express the Philadelphia chromosome mutation as part of their leukemia, that specifically targets cells with this mutation?
Nilotinib
Rituximab
Cyclophosphamide
Doxorubicin
In which of the following phases of CML would the patient be expected to have the best response to therapy?
Chronic phase
Accelerated phase
Blast crisis phase
Maintenance phase
Which of the following signs/symptoms can often be associated with an infection in an immunocompromised patient?
Musculoskeletal pain
Fever
Vision changes
Jaundice
