wayground logo

Free Printable Worksheets

NEW

Font size

S
M
L
XL
Worksheets

Pharmacokinetics

Total questions: 20

Worksheet time: 11mins

Name
Class
Date
1.

ABSORPTION: Absorption refers to the amount of drug that enters the ____________

a)

bloodstream

b)

liver

c)

pancreas

d)

target tissue

2.

ABSORPTION: If 30% of a drug loses it's efficacy, the Bioavailability will be ___________

a)

negative

b)

70%

c)

30%

d)

15%

3.

Alternative routes of administration like suppository, intravenous, intramuscular, inhalational aerosol, transdermal and sublingual avoid the first-pass effect because they allow drugs to be absorbed directly into the systemic circulation.

a)

True

b)

False

4.

ABSORPTION: Intravenous drugs have __________ bioavailability.

a)

zero

b)

50%

c)

full

d)

100%

5.

ABSORPTION: _________ is an example of an antibiotic that is normally used IV to treat serious infections because it is so poorly absorbed orally.

a)

vancomycin

b)

clindamycin

c)

azithromycin

d)

gentamycin

6.

DISTRIBUTION: One class of drugs that we discussed that requires therapy management for appropriate measurements includes:

a)

topical agents

b)

aerosol inhalers

c)

seizure meds

d)

antidepressants

7.

DISTRIBUTION: A drug bound to a protein is _____________

a)

active

b)

mobile

c)

free

d)

inactive

8.

DISTRIBUTION: ___________is the main protein that binds medications in the blood.

a)

albumin

b)

thrombin

c)

insulin

d)

oxytocin

9.

DISTRIBUTION: Medications with a large volume of distribution generally have a ___________ blood concentration.

a)

larger

b)

lower

c)

similar

d)

stable

10.

DISTRIBUTION: Most medications require a loading dose TRUE or FALSE

a)

True

b)

FALSE

11.

METABOLISM: The metabolism of medication is the _______ ______ ________ in the body

a)

elimination of medication

b)

production of enzymes

c)

breakdown of medication

d)

altered chemical reaction

12.

METABOLISM: Metabolites are the altered chemical forms of the drug. TRUE or FALSE

a)

true

b)

false

13.

METABOLISM: CYP enzymes are very active in converting a drug to it's ___________.

a)

protein

b)

onset

c)

molecule

d)

metabolite

14.

METABOLISM: Which of the following is a disadvantage of a long acting metabolite

a)

wider distribution

b)

prolonged side effects

c)

prolonged effect

d)

decreased metabolism

15.

METABOLISM: A drug administered in an inactive form is called a(n) __________

a)

enzyme

b)

altered drug

c)

pro drug

d)

metabolite

16.

EXCRETION: ____________ refers to the removal of a drug from the body, mainly in the urine or feces.

a)

metabolism

b)

distribution

c)

transfer

d)

elimination

17.

EXCRETION: The correct term to indicate "half life" is:

a)

T 1/2

b)

1/2 H

c)

HL

d)

1/2 T

18.

EXCRETION: Half life refers to the time it takes for 50% of a drug to be _____________.

a)

metabolized

b)

eliminated

c)

cleared

d)

induced

19.

EXCRETION: A drug with low clearance will typically have a __________ half life.

a)

typical

b)

altered

c)

long

d)

shortened

20.

EXCRETION: The most common location of drug excretion in the body is the __________.

a)

liver

b)

small intestines

c)

large intestines

d)

kidneys