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Worksheets

Cytokines

Total questions: 15

Worksheet time: 5mins

Name
Class
Date
1.

What is a more commonly used name for the specific immune system?

a)

adaptive

b)

innate

2.

This system provides a rapid, early response to invading microorganisms; what is considered the second line of cellular immune defense?

a)

Adaptive

b)

Skin

c)

Innate

d)

Tears

3.

From the cells listed, which is the first cell of the immune system to respond to a pathogenic microorganism?

a)

B cell

b)

Helper T cell

c)

Macrophage

d)

Cytotoxic T cell

4.

What cytokine is produced by a plasmacytoid dendritic cell when it detects a virus infected cell? This in turns "warns" neighboring cells of the virus attack.

a)

Interferon-alpha

b)

Complement C3b

c)

IL-1beta

d)

Interferon-gamma

5.

Which of the following is considered an anti-inflammatory cytokine?

a)

INF-gamma

b)

IL-1b

c)

IL-4

d)

IL-10

6.

What cytokine is produced by macrophages to induce liver production of acute phase proteins?

a)

IFN-b

b)

IL-5

c)

IL-6

d)

IL-7

7.

Which cytokine is made by macrophages and increases IFN-gamma production in NK cells?

a)

IL-1

b)

IL-4

c)

IL-10

d)

IL-12

8.

Which cytokine is made by several cells and is considered an inhibitor of inflammation and also causes differentiation of TH17 cells

a)

TNF-alpha

b)

TGF-beta

c)

IL-7

d)

IL-3

9.

Which cytokine promotes humoral immunity and is produced by Th2 cells?

a)

INF-beta

b)

IL-4

c)

IL-6

d)

IL-17

10.

Which cytokine promotes cell-mediated immunity and is produced by Th1 cells?

a)

INF-gamma

b)

IL-4

c)

IL-6

d)

IL-10

11.

Which chemokine is involved in recruiting neutrophils to the extravascular space during acute inflammation?

a)

CCL2 (MCP-1)

b)

CXCL2 (MIP-2)

c)

CXCL8 (IL-8)

12.

Which cytokine promotes the growth of all hematopoetic multi-lineage precursor cells in bone marrow?

a)

IL-2

b)

IL-3

c)

IL-4

d)

IL-5

13.

What cell type makes type I IFN's?

a)

Mast cell

b)

Plasmacytoid dendritic cell

c)

Monocyte

d)

Neutrophil

14.

Which cytokine, IL-1 or IL-10, is considered to be pro-inflammatory?

a)

IL-1

b)

IL-10

15.

What is a function of C-reactive protein (CRP) as an acute phase reactant?

a)

Removes iron from gut

b)

Modifies cholesterol metabolism

c)

Promotes the activation of Complement

d)

Modulates wound healing response