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Biology Semester 1

Total questions: 40

Worksheet time: 37mins

Name
Class
Date
1.

Which of the following is NOT the importance of DNA replication?

a)

To ensure each daughter cell receives the same number chromosome

b)

To increase genetic variation

c)

To synthesize histone proteins

d)

To increase the amount of DNA

2.
Identify the phase of mitosis
a)

Prophase

b)

Metaphase

c)

Anaphase

d)

Telophase

3.

During the process of meiosis, chromosomes replicate

a)

once, during interphase I

b)

once, during interphase II

c)

twice, during prophase I and II

d)

twice, during interphase I and II

4.
The set of genes carried by an organism is called this.
a)
dominant
b)
genotype
c)
phenotype
d)
recessive
5.
A trait that will always be expressed in the phenotype if it is in the genotype.
a)
acquired
b)
dominant
c)
hybrid
d)
recessive
6.
What pattern of inheritance is shown in this image?
a)
Codominance
b)
Incomplete dominance
c)
Polygenic traits
7.

Which of these can change allele frequencies in a population?

a)

Sexual selection

b)

Genetic drift

c)

Gene flow

d)

Natural selection

e)

All of these can change allele frequencies

8.

The ability to taste PTC is controlled by the dominant allele T, while the inability to taste PTC is controlled by the recessive allele t,  In a population, 70% can taste PTC.  By assuming the population is in equilibrium, what is the frequency of allele t in the population mentioned?

a)

0.20

b)

0.30

c)

0.55

d)

0.55

9.

Which of the following help to hold the DNA strands apart while they are  being replicated?

a)

Primase

b)

Single-strand binding protein

c)

DNA Ligase

d)

Primase

10.

Which RNA bases would pair with 3'TACGAA5' in transcription

a)

5'AUGCUU3'

b)

5'ATGCTT3'

c)

5'GCATCC3'

d)

5'GCAUCC3'

11.
What would happen if we did not have start codons?
a)
Polypeptide chains would continue to grow
b)
Amino acids would bind to tRNA
c)
Protein synthesis wouldn't occur
d)
mRNA would form a double strand
12.

Why is only one strand of DNA transcribed into mRNA?  

a)

Because mRNA is only required in small quantities.

b)

Because the other strand would produce the same amino acid sequence in reverse order.

c)

Because all genes are located on the same DNA strand, while the other strand acts as protection.

d)

Because transcribing both DNA strands would produce different amino acid sequences.

13.
A protein that binds to the operator and blocks the RNA polymerase
a)
regulator
b)
repressor
c)
activator
d)
corepressor
14.

The lac operon genes only become expressed if:

a)

allolactose binds to the repressor protein

b)

glucose binds to the repressor protein

c)

lactose binds to the lac operator

d)

the repressor protein binds to the lac operator

15.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
a)
Base Substitution
b)
Base Insertion
c)
Base Inversion
d)
Translocation
16.
Which of the following would result in a frameshift mutation?
a)

Base Insertion only

b)

Base Substitution only

c)

Base Deletion only

d)

Base Insertion and Base Deletion

17.
What type of chromosomal mutation is this?
a)
Inversion
b)
Translocation
c)
Deletion
d)
Duplication
18.

The illustration shows the result of which effect of mutation?

a)

Silent mutation

b)

Missense mutation

c)

Nonsense mutation

19.

Which of the following is a circular DNA from bacteria that can hold a foreign DNA?

a)

plasmid

b)

restriction enzyme

c)

ligase

d)

protein expression

20.
What is the enzymatic function of restriction enzymes?
a)
To add new nucleotides to the growing strand of DNA.
b)
To join nucleotides during replication.
c)
To join nucleotides during transcription.
d)
To cleave nucleic acids at specific sites.
21.
What is a cloning vector?
a)
The DNA probe used to locate a particular gene in the genome.
b)
An agent such as plasmid, used to transfer DNA from an in vitro solution into a living cell.
c)
The laboratory apparatus used to clone genes.
d)
An enzyme that cuts DNA into restriction fragments.
22.

The first step to genetic engineering is:

a)

isolate desired gene

b)

Cut DNA strand

c)

Reconnect DNA fragements

d)

Produce proteins

23.

The unpaired nucleotide sequences produced by the action of restriction enzymes are referred to as

a)

sticky ends

b)

base pairs

c)

single strands

d)

restriction fragments

24.

Which of the following is correct about host cell?

a)

Plasmid is an example of host cell.

b)

Unable to receive DNA molecule through transformation.

c)

An organism that prevents cloning vectors from multiplying.

d)

An organism that is used to receive recombinant DNA for cloning purposes.

25.

The graph above shows the level of hormones in the female reproductive cycle.


Which of the following shows the menstrual period?

a)

I

b)

II

c)

III

d)

IV

26.

Which of the following statements is NOT TRUE about hormonal control during birth in humans?

a)

The posterior lobe of pituitary gland secretes the oxytocin hormone.

b)

The anterior lobe of the pituitary gland secretes the prolactin hormone.

c)

The release of the prostaglandins hormone from the placenta is increased.

d)

The level of progesterone hormone in blood is higher than estrogen hormone.

27.

Arrange the CORRECT sequence of sperm movement.

1. Urethra

2. Ejaculatory duct

3. Release from body

4. Epididymis

5. Vas deferens

6. Seminiferous tubule

a)

4, 5, 6, 1, 2, 3

b)

4, 6, 5, 1, 2, 3

c)

6, 4, 5, 2, 1, 3

d)

6, 5, 4, 1, 2, 3

28.

Which of the following is true about fruit development after double fertilisation?

a)

The diploid zygote develops into the cotyledon

b)

The ovule develops into the fruit

c)

The integuments develop into seed coat

d)

The triploid nucleus develops into the embryo

29.

When does the secondary oocyte complete its second meiotic division?

a)

When the corpus luteum degenerates

b)

During ovulation

c)

When it is penetrated by a sperm

d)

While waiting for the arrival of sperm in the Fallopian tube

30.

A fertilized egg undergoes several stages before it is successfully implanted. The diagram below shows these stages as the fertilized egg travels through the female reproductive system.

In which of the following structures of the female human reproductive system is the blastocyst implanted during normal human development?

a)

Overy

b)

Uterus

c)

Vagina

d)

Amniotic sac

31.

The pattern of growth shown by Shorea sp., a woody plant found in the tropical rainforests is ..........

a)

Limited growth

b)

Unlimited growth

c)

Allometric growth

d)

Isometric growth

32.

What are polyribosomes?  

a)

Groups of ribosomes reading a single mRNA simultaneously.

b)

Ribosomes containing more than two subunits.

c)

Multiple copies of ribosomes associated with giant chromosomes.

d)

Aggregations of vesicles containing ribosomal RNA.

33.

Which of the following enzyme will make staggered cuts?

a)

EcoRI

b)

SmaI

c)

DNA ligase

d)

Reverse transcriptase

34.

Which of the following statement describe Annealing in PCR?

a)

To catalyse the synthesis of the second DNA strand   

     forming double stranded cDNA

b)

To catalyses the synthesis of the single strand complementary DNA

c)

The joining of DNA primers complementary to sequences DNA template

d)

The joining of the RNA primer complementary to the sequences of DNA template

35.

Which of the following is the NOT the difference between plasmid and chromosome?

a)

Plasmid can be used as cloning vector while chromosome cannot be used as cloning vector

b)

Plasmid not associate with histone protein while chromosome is associate with histone protein

c)

Plasmid involve in heredity while chromosome does not involve in heredity

d)

Plasmid is circular while chromosome is linear or circular

36.

What happens to the embryo sac after fertilisation?

a)

Develop into seed

b)

Differentiate into plumule

c)

Differentiate into radicle

d)

Develop into ovule

37.

All of the following is the structure of blastocyst EXCEPT

a)

Trophoblast

b)

Morula

c)

Blastocoel

d)

Inner cell mass

38.

Which of the following that cause genetic variation?

a)

Synapsis

b)

Cytokinesis

c)

DNA replication

d)

Random arrangement

39.

Which of the following describe allometric growth?

a)

Change in size is not accompanied by change in shape of the organism.

b)

Change in size is accompanied by change in shape of the organism.

c)

Growth is complete when the organism achieves its maximum size.

d)

Growth continues until death

40.

Why estrogen increase at the end of pregnancy?

a)

To stimulate formation of oxytocin receptor

b)

To stimulate development of placenta

c)

To stimulate hormone prolactin

d)

To stimulate ovulation