WorksheetsGenetic Disorders
Total questions: 28
Worksheet time: 20mins
Name
Class
Date
1.
Which disease or disorder is caused by the inheritance of two mutated alleles?
a)
Down Syndrome
b)
Colorblindness
c)
Cystic Fibrosis
d)
Hemophilia
2.
Which disease or disorder causes people to have abnormal hemoglobin?
a)
Cystic Fibrosis
b)
Albinism
c)
Sickle-cell Disease
d)
Down Syndrome
3.
Which disease or disorder is the result of having an extra chromosome?
a)
Cystic Fibrosis
b)
Down Syndrome
c)
Colorblindness
d)
Sickle-cell Disease
4.
What are the two ways that genetic disorders can be inherited?
a)
Through blood transfusions and meiosis.
b)
Mutations in DNA and changes in structure or number of chromosomes.
c)
Missing chromosomes or premature egg splitting.
d)
Unhealthy environments and heredity.
5.
What is the name of the protein that is not normal in people with sickle-cell disease?
a)
mucus
b)
clotting protein
c)
karyotype
d)
hemoglobin
6.
A doctor may use a _________ to examine the chromosomes in a cell.
a)
x-ray
b)
blood test
c)
karyotype
d)
hemoglobin
7.
Which genetic disorder or disease is a sex-linked trait and carried on the X chromosome?
a)
Cystic Fibrosis
b)
Sickle-cell Disease
c)
Hemophilia
d)
Down Syndrome
8.
What type of disorder is sickle cell anemia
a)
Autosomal dominant
b)
Autosomal recessive
c)
X-linked dominant
d)
X-linked recessive
9.
X linked recessive traits affect mostly
a)
males
b)
females
c)
both equally
d)
none of the above
10.
What genetic disorder causes the body to produce unusually thick mucus in the lungs and intestines?
a)
Cystic Fibrosis
b)
Sickle Cell
c)
Down Syndrome
d)
Hemophilia
11.
If one of your parents has Huntington's, what is your chance of inheriting it?
a)
0%
b)
25%
c)
50%
d)
75%
e)
100%
12.
What part of a person's body breaks down due to Huntington's?
a)
Nerve cells in the brain
b)
Bone marrow
c)
White blood cells
d)
Arteries
13.
This is an example of ___________.
a)
Incomplete Dominance
b)
Codominance
14.
What mutation has occurred here?
T-G-A-C-C-A
T-G-A-G-C-A
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift
15.
A condition in which a person's skin, hair, and eyes lack normal coloring is called
a)
pigment disease
b)
albinism
c)
pink eye syndrome
d)
cystic fibrosis
16.
Mutated DNA sequences that can be passed from parent to offspring --
a)
occur in somatic cells (body cells)
b)
occur in gametic cells (sex cells)
c)
are rejected by meiosis
d)
only occur if the parent is exposed to harmful substances
17.
What can cause birth defects?
a)
Environmental factors
b)
Genetic factors
c)
Food choices
d)
Standing near smokers
18.
There are _______ autosomes in humans.
a)
2
b)
23
c)
46
d)
44
19.
If a gene is found only on the X chromosome and not the Y chromosome, it is said to be what?
a)
sex-linked trait
b)
polygenic trait
c)
codominant trait
d)
incomplete dominance trait
20.
Which condition is inherited as a dominant allele?
a)
cystic fibrosis
b)
albinism
c)
Huntington's disease
d)
Tay-Sacs disease
21.
Disorder when blood cells are misshapen, resulting in a decrease of oxygen and caused by a defective allele for a polypeptide in hemoglobin
a)
Duschenne's muscular dystrophy
b)
Turner's Syndrome
c)
sickle cell anemia
d)
Down Syndrome
22.
What is hemophilia?
a)
a severe form of the common cold
b)
another name for Darwin's idea of Natural Selection
c)
an inherited disease that is caused by the absence of a blood clotting factor
d)
someone with both male and female sex organs
23.
T12 - Identify the gene mutation:
Normal
AGC-TTA-CGT-AAA
Mutant
ACT-TAC-GTA-AA
Normal
AGC-TTA-CGT-AAA
Mutant
ACT-TAC-GTA-AA
a)
insertion frameshift
b)
deletion frameshift
c)
insertion
d)
nonsense
24.
T12 - Adding or deleting DNA bases and causing the reading frame to shift is called a(n)
a)
Inversion
b)
Translocation
c)
Substitution
d)
Frameshift
25.
T13 - Nondisjunction is related to a number of serious human disorders. How does nondisjunction cause these disorders?
a)
alters the number of zygotes
b)
alters the chromosome structure
c)
alters the number of gametes
d)
alters the number of chromosomes
26.
Any change in the sequence of DNA is...
a)
transgenic shift
b)
Single Genotype
c)
Monohybrid Trait
d)
Mutation
27.
Which disorder is characterized by the inability to break down a specific amino acid and can be treated by a special diet?
a)
Huntington's
b)
Tay Sachs
c)
Cystic fibrosis
d)
PKU
28.
A person that has sickle-cell anemia trait and more resistant to
a)
measles
b)
polio
c)
typhoid
d)
malaria
100 %
