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3.5 IB Restriction Endonucleases

Total questions: 20

Worksheet time: 42mins

Name
Class
Date
1.

If the target sequence or restriction site is 5'GCTTCG3', what is the complementary sequence read in the 3'-5' direction?

a)

CGAAGC

b)

GCTTCG

c)

CGUUCG

d)

GCUUCG

2.

What is a restriction enzyme?

a)

An enzyme that cuts DNA

b)

An enzyme that add to the DNA strand

c)

An enzyme that builds proteins

d)

An enzyme that breaks down lipids

3.

A special protein that targets a specific base sequence and cuts DNA into smaller fragments.

a)

PCR

b)

DNA Polymerase

c)

Helicase

d)

Restriction Enzyme

4.

What is the term given to symmetrical ends of DNA after being cut by a restriction enzyme?

a)

Blunt Ends

b)

Sticky Ends

c)

Ligated Ends

d)

Restrictive Ends

5.

This biomolecule originates from bacterial DNA and has the ability to cut DNA....

a)

Helicase

b)

Ligase

c)

Restriction Enzyme

d)

DNA Polymerase

6.

DNA cutting "scissors" are more correctly referred to as....

a)

Bacteriophages

b)

Restriction Enzymes

c)

DNA Enzymes

d)

Plasmids

7.

The unpaired nucleotides produced by the action of restriction enzymes are referred to as.....

a)

sticky end.

b)

base sequence.

c)

single strands.

d)

restriction fragments.

8.

The recognition sites for restriction enzymes are usually...

a)

alliterations

b)

pallindromes

c)

acronyms

d)

analogies

9.

Restriction Enzymes are isolated from....

a)

proteins

b)

bacteria

c)

viruses

d)

bacteriophages

10.

Restriction Enzymes were primarily used as....

a)

defense by protozoa against antibiotics

b)

tools by viruses to cleave bacterial genome

c)

defense by bacteria against bacteriophages viruses

d)

tools to cleave DNA during replication

11.

What is a palindrome?

a)

A sticky end resulting from a restriction enzyme

b)

A blunt end resulting from a restriction enzyme

c)

A sequence that reads the same forwards and backwards

d)

A sequence that is complementary to the other

12.

Which restriction enzymes from above make blunt cuts? (2)

a)

Alul

b)

HaeIII

c)

BamHI

d)

HindIII

e)

EcoRI

13.

Which restriction enzymes from above make sticky cuts? (3)

a)

Il

b)

HaeIII

c)

BamHI

d)

HindIII

e)

EcoRI

14.

How many fragments resulted from the cut above?

a)

1

b)

2

c)

3

d)

4

15.

How many base pairs (bp's) make up each fragment?

a)

11

b)

14

c)

7

d)

22

e)

28

16.

Another name for "recognition site" is...

a)

nucleotide

b)

restriction Site

c)

primer

d)

construction site

17.

What kind of cuts were made in the scenario above?

a)

Blunt

b)

Sticky

c)

No cuts were made

d)

Palindrome

18.

Restriction enzymes need the right temperature in order to work . . .

a)

to recreate the conditions found in the particular bacteria at which the enzyme was sourced

b)

so they can cut the DNA

c)

to recreate the conditions found in the human body cell

d)

they can work at any temperature as they are sourced from extremophiles

19.

Another name for a restriction enzyme is...

a)

an endonuclease

b)

an extremophile

c)

Taq polymerase

d)

a pallindromic ligase

20.

What is a plasmid?

a)

Chloroplast DNA

b)

Mitochondrial DNA

c)

A bacterial chromosome

d)

Small circle of DNA that can transfer genes to or from a prokaryote