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Adaptive Immunity

Total questions: 50

Worksheet time: 23mins

Name
Class
Date
1.

Most microbes enter the body through the:

a)

The anal route

b)

The parenteral route

c)

The gastrointestinal route

d)

The respiratory route

2.

Which type of adaptive immunity focuses on extracellular pathogens, e.g. bacteria?

a)

Cell-mediated

b)

Innate

c)

Antigen-specific

d)

Humoral

3.

The formation of blood cells in bone marrow is termed:

a)

Cytokinesis

b)

Interferonesis

c)

Hematopoiesis

d)

Interleukinization

4.

The mechanism of host cell TLRs binding to PAMPs is similar to:

a)

B-cell maturation in the thymus

b)

Clonal selection in B-cells

c)

Antibodies binding to antigen epitopes

d)

B-cells binding to T-cells

5.

Which of these statements is true for the leukocytes?

a)

Leukocytes are red blood cells.

b)

Basophils secrete histamine and are involved in inflammation

c)

Neutrophils are part of adaptive immunity.

d)

Eosinophils are professional phagocytes.

6.

Which immunoglobulin is responsible for the inflammatory response in regards to parasitic worms?

a)

IgB

b)

IgA

c)

IgG

d)

IgE

7.

Which type of MHC would you find on macrophages?

a)

MHC-I

b)

MHC-2

c)

MHC-3

d)

All of these

8.

Immune cells must be able to:

a)

Self-discriminate

b)

Self-specificity

c)

Self-tolerate

d)

All of these

9.

Which type of MHC would you find on a liver cell?

a)

MHC-I

b)

MHC-2

c)

MHC-3

d)

All of these

10.

Which of the following clusters of differentiation interact with B-cells?

a)

CD4+

b)

CD8+

c)

TH17

d)

TH2

11.

Responsible for protecting intestinal microbiota against immune cells.

a)

Interleukins

b)

Cytotoxic T-cells

c)

T-helper cells

d)

T-regulatory cells

12.

Which of the following induces apoptosis:

a)

Blebbin

b)

Cadherin

c)

Granzyme

d)

More than one of these

13.

Responsible for attacking viruses, tumors, and parasites:

a)

Natural killer cells

b)

Terminator cells

c)

Eosinophils

d)

All of these

14.

Method used by the immune system to attack large pathogens.

a)

Apoptosis

b)

ADCC

c)

Blebbing

d)

Inflammation

15.

__________________ memory occurs after the second exposure to an antigen.

a)

Anamnestic

b)

IgM

c)

Memory

d)

IgG

16.

Becky contracts chickenpox after babysitting kids in the neighborhood. What type of immunity does she have?

a)

Artificially acquired active

b)

Naturally acquired active

c)

Artificially acquired passive

d)

Naturally acquired passive

17.

Gregory received the shingles vaccine at his yearly physical. What type of immunity does he have?

a)

Naturally acquired active

b)

Naturally acquired passive

c)

Artificially acquired active

d)

Artificially acquired passive

18.

Which antibody is released in the greatest amounts after second exposure to a specific antigen?

a)

IgA

b)

IgM

c)

IgG

d)

IgE

19.

IgM is associated with immunological memory.

a)

True

b)

False

20.

Which is NOT true regarding humoral immunity?

a)

Produces antibodies that combat foreign antigens

b)

Involves B cells

c)

Fight intracellular pathogens

d)

Associated cells are matured in red bone marrow

21.

Which is NOT true regarding cell-mediated immunity?

a)

Produces antibodies that combat foreign antigens

b)

Involves T cells

c)

Fight extracellular pathogens

d)

Associated cells are matured in thymus

22.

B cells mature in the:

a)

thyroid

b)

yellow bone marrow

c)

red bone marrow

d)

thymus

23.

T cells mature in the:

a)

thyroid

b)

yellow bone marrow

c)

red bone marrow

d)

thymus

24.

All antigens are microbial.

a)

True

b)

False

25.

Incomplete antigens that stimulate allergic responses:

a)

epitopes

b)

antibodies

c)

antigens

d)

haptens

26.

Antibodies are also called:

a)

antigens

b)

haptens

c)

agglutinates

d)

immunoglobulins

27.

Primary antibody of primary immune response:

a)

IgM

b)

IgG

c)

IgA

d)

IgE

e)

IgD

28.

Primary antibody in secondary immune response

a)

IgM

b)

IgG

c)

IgA

d)

IgE

e)

IgD

29.

Can cross the placenta:

a)

IgM

b)

IgG

c)

IgA

d)

IgE

e)

IgD

30.

Common in mucous membranes, saliva, tears, and breast milk:

a)

IgM

b)

IgG

c)

IgA

d)

IgE

e)

IgD

31.

Common in humoral response; found on B cells:

a)

IgM

b)

IgG

c)

IgA

d)

IgE

e)

IgD

32.

Cause the release of histamines when bound to antigen; lysis of parasitic worms

a)

IgG

b)

IgD

c)

IgE

d)

IgA

e)

IgM

33.

Antibodies are created using:

a)

clonal selection

b)

thymic selection

c)

hematopoiesis

d)

binary fission

34.

B cells that cannot self-discriminate go through the process of:

a)

clonal selection

b)

clonal deletion

c)

thymic selection

d)

hematopoiesis

35.

T-cells are created using:

a)

clonal selection

b)

thymic selection

c)

hematopoiesis

d)

binary fission

36.

An ___________ forms when antibodies bind to antigens

a)

antigen–antibody complex

b)

epitope

c)

affinity

d)

avidity

37.

The strength of the bond between antibody & antigen is:

a)

avidity

b)

axillity

c)

affinity

d)

epitopicity

38.

Clumping of bacterial cells due to AAC:

a)

Antibody-dependent cell-mediated cytotoxicity (ADCC)

b)

Opsonization

c)

Neutralization

d)

Agglutination

e)

Activation of complement

39.

Coating of antigen with antibody to increase phagocytoisis:

a)

Antibody-dependent cell-mediated cytotoxicity (ADCC)

b)

Opsonization

c)

Neutralization

d)

Agglutination

e)

Activation of complement

40.

Blocks adherence of pathogen to host mucosa:

a)

Antibody-dependent cell-mediated cytotoxicity (ADCC)

b)

Opsonization

c)

Neutralization

d)

Agglutination

e)

Activation of complement

41.

Can result in opsonization, cytolysis, & inflammtory responses:

a)

Antibody-dependent cell-mediated cytotoxicity (ADCC)

b)

Opsonization

c)

Neutralization

d)

Agglutination

e)

Activation of complement

42.

Antibodies attach to large phagocytosis-resistant pathogens and poke holes in them:

a)

Antibody-dependent cell-mediated cytotoxicity (ADCC)

b)

Opsonization

c)

Neutralization

d)

Agglutination

e)

Activation of complement

43.

Antigen presenting cells:

a)

present antigen to B cells

b)

are red blood cells

c)

are cytokines

d)

present antigen to T cells

44.

CD4 T cells are also called:

a)

B-cells

b)

T-cytotoxic cells

c)

T-helper cells

d)

Red blood cells

45.

CD8 T cells are also called:

a)

B-cells

b)

T-cytotoxic cells

c)

T-helper cells

d)

Red blood cells

46.

Bind to MHCII on APC's and interact directly with antigens:

a)

CD8

b)

CD4

47.

Bind to MHCI on infected/altered host cells:

a)

CD8

b)

CD4

48.

Trigger apoptosis:

a)

CD8

b)

CD4

49.

The relative amount of antibody in the host's serum:

a)

Antibody titer

b)

Anamnestic memory

c)

Serology

d)

Antiserum

50.

Some immune cells work in both innate and adaptive immune responses.

a)

True

b)

False

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