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Platelets and Blood Clotting Assignment

Total questions: 10

Worksheet time: 4mins

Name
Class
Date
1.

Which of the following substances is found in

the dense granules of platelets?

a)

Platelet-derived Growth Factor

b)

von Willebrand factor

c)

Serotonin

d)

Fibrinogen

2.

Which of the following statements is correct regarding the platelet membrane?

a)

The lipid layer is comprised mainly of phospholipids

b)

Thrombin facilitates binding to sub-endothelium

c)

Platelet phospholipid facilitates binding of Factor XII

d)

Thromboxane is made from membrane glycoproteins

3.

Which of the following substances promotes platelet activation?

a)

Protein S

b)

Prostacyclin

c)

Nitric Oxide

d)

ADP

4.

What is the three step process that stops blood flowing from a cut called?

a)

haemostasis

b)

homeostasis

c)

coagulation

d)

agglutination

5.

What is the name of the protein that is released by platelets in response to an injury?

a)

haemoglobin

b)

glucose

c)

fibrin

d)

carbon dioxide

6.

The exposure of tissue factor to blood starts which process?

a)

platelet adhesion

b)

platelet aggregation

c)

the coagulation cascade

d)

vasoconstriction

7.

What is the name of the soluble factor that results in fibrinolysis?

a)

plasmin

b)

tissue plasminogen activator

c)

fibrin degradation product

d)

alpha 2 antiplasmin

8.

Which pathway is represented by the diagram shown?

a)

Extrinsic pathway

b)

Intrinsic pathway

c)

Common pathway

d)

none of the above

9.

Which of the following clotting factors are activated by thrombin? Select all that apply

a)

Factor V

b)

Factor X

c)

Factor XIII

d)

Factor XI

10.

A 4-year-old male is seen at the University Hospital for recurrent joint bleeds. Coagulation tests revealed: PT 14/11 sec, PTT 47/29 sec. Which of the following coagulation factor deficiencies is compatible with this result?

a)

Factor X

b)

Factor IX

c)

Factor V

d)

Factor XIII