WorksheetsMutation Test
Total questions: 15
Worksheet time: 8mins
Name
Class
Date
1.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
2.
ATTTGAGCC- Original
ATTGAGCC - Mutated
The example above is an example of a
ATTGAGCC - Mutated
The example above is an example of a
a)
Insertion- Frameshift
b)
Deletion- Substitution
c)
Deletion -Frameshift
d)
All of the above
3.
Why are insertion and deletion (frameshift) mutations so harmful?
a)
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
b)
They insert things that an organism doesn't need.
c)
They often delete things that organisms need.
d)
Insertion and deletions are not any more harmful than substitution mutations.
4.
What kind of mutation would have the greatest effect on the protein?
a)
Missense- 1 amino is changed
b)
Silent- no amino acids are changed
c)
Frameshift- all amino acids after the mutation are changed
5.
a change in one DNA triplet that may result in a new triplet that codes for a stop codon instead of an amino acid is known as
a)
missense
b)
nonsense
c)
frameshift
d)
silent
6.
Nonsense mutations result in ____________________.
a)
a stop codon
b)
the same amino acid as the original
c)
a different amino acid than the original
7.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
a)
Base Substitution
b)
Base Insertion
c)
Base Inversion
d)
Translocation
8.
A mutation that does NOT show up through protein function is called
a)
deletion mutation
b)
inversion mutation
c)
silent mutation
d)
transverse mutation
9.
A nonsense mutation produced _________.
a)
A same polypeptide chain
b)
A slightly altered polypeptide chain
c)
A shift in the reading frame
d)
The regulatory sequence being altered.
10.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
11.
Which shows a mutated segment of DNA?
ATTCGC
ATTCGC
a)
UAAGCG
b)
TAAGCG
c)
TAGGCG
12.
Mutations affect the ________ of a protein. Because of this the proteins ______ is affected as well.
a)
gene, function
b)
sequence, gene
c)
shape,function
13.
if a single nucleotide base is added or deleted the entire reading frame will?
a)
shift, causing a frameshift mutation
b)
move, causing a delection
c)
move, causing an addition
d)
shift, causing a deletion
14.
Example of disease cause by substitution mutation
a)
Heamophilia
b)
Colour blind
c)
Turner syndrome
d)
SIckle cell anemia
15.
Example of polyploidy in organism
a)
Syndrome triple X
b)
Klinefelter syndrome
c)
Turner syndrome
d)
watermelon without seeds
100 %
