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Worksheets2.7_ IB Biology past paper_ DNA replication
Total questions: 19
Worksheet time: 15mins
This is a sequence of nucleotides from a section of mRNA.
AUGAAACGCACGCAG
From which DNA sequence has it been transcribed?
ATGAAACGCACGCAG
UACUUUGCGUGCGAC
TACUUUGCGTGCGTC
TACTTTGCGTGCGTC
How is the information in the genetic code used?
To predict the genotype of gametes
To distinguish prokaryotic genomes from eukaryotic genomes
To deduce phenotypes in pedigree charts
To translate mRNA into polypeptides
What is required to replicate DNA?
Temperature of 37 °C
Free nucleotides carrying A, C, G and T bases
Plasmids
Endonuclease
The gene that codes for a particular polypeptide includes the base sequence shown.
GAGTACCCT
What is the base sequence of the mRNA molecule which is complementary to this sequence?
GAGTACCCT
CTCATGGGA
GUGTUCCCT
CUCAUGGGA
The base sequences of a short section of DNA are shown, together with mRNA that has been transcribed from it and one of the tRNA anticodons that could be used to translate the mRNA.
Which strand of DNA is transcribed and to which codon in the mRNA would the tRNA anticodon bind during translation?
DNA strand 1, second
DNA strand 2, second
DNA strand 1, third
DNA strand 2, third
Where are amino acids joined together to make polypeptides?
Nucleus
Nucleolus
Golgi apparatus
Ribosomes
The table shows some codons for five amino acids.
Which of these DNA strands will code for the amino acid sequence glycine-serine-glycine?
CCUUCGCCG
CCTTCGCCG
GGAAGCGGA
CCUUCGCCU
What do DNA replication, transcription and translation have in common?
Take place in cell nucleus
Require free nucleotides
Catalysed by polymerase
Complementary base pairing
Some yeast genes can be replaced by human genes that then continue to produce the same human proteins in the yeast cells. Which statement helps to explain this evidence?
The DNA of yeast and humans is identical.
Yeast and humans have the same number of chromosomes.
The genetic code is universal.
Yeast and humans are both eukaryotes.
What do DNA replication, transcription and translation have in common?
Take place in cell nucleus
Require free nucleotides
Catalysed by polymerase
Complementary base pairing
Meselson and Stahl investigated DNA replication by first feeding bacteria with bases containing 15N (heavy), and then with bases containing 14N (light). The results are shown in the photographs.
From this information, what would be the composition of the DNA in generation 3?
There will be a single 14N band.
There will be a single 15N band and a single 14N band.
There will be a darker 14N band and a lighter hybrid band.
There will be a single 15N band, a single hybrid band and a single 14N band.
A short sequence of nucleotides reads GGACAGAGCGCAGACGA. In which type of molecule could this sequence be found?
DNA molecule only
RNA molecule only
Both in a DNA and an RNA molecule
In double-stranded DNA only
The table shows the genetic code.
Which mRNA could code for the sequence Met-Ser-Leu-Arg-Phe?
AUG UCA UCG UGG UUU
AUG UCC ACC AGA UUC
AUG UCU CCC AGA UUU
AUG UCG CUG AGG UUC
Meselson and Stahl conducted experiments using the isotopes 14N and 15N which showed that DNA replication is semi-conservative. What would they have observed about the distribution of isotopes in the DNA after one round of replication if DNA replication was conservative rather than semi-conservative?
Only 14N DNA
Only 15N DNA
All DNA half 14N and half 15N
Half the DNA with only 14N and half with only 15N
The bacterium Neisseria gonorrhoeae causes infections related to the human reproductive system. The graph shows the percentage of samples in which this bacterium showed resistance to six antibiotics over a period of ten years.
What is a possible explanation for the total percentage resistance being larger than 100% in 2010?
People do not take the antibiotics as prescribed.
More people have been sampled in that year.
There was an epidemic of Neisseria gonorrhoeae in that year.
Some bacteria are resistant to more than one antibiotic.
Which are necessary to make DNA replication semi-conservative?
I. Separation of the strands by RNA polymerase
II. Complementary base pairing
III. Use of a pre-existing strand as a template
I and II only
I and III only
II and III only
I, II and III
A strand of mRNA consists of the following nucleotides:
AUUCUGGCUA
Which of the following represents the non-transcribed (sense) strand of the DNA?
TAAGACCGAT
ATTCTGGCTA
UAAGACCAU
AUUCUGGCUA
What enables bacteria to produce human growth hormone?
DNA replication is semi-conservative.
The polymerase chain reaction can be used.
They need the hormone for growth.
The genetic code is universal.
