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AP Bio Unit 4

Total questions: 50

Worksheet time: 36mins

Name
Class
Date
1.
A signal molecule that binds to a plasma-membrane protein is a
a)
ligand
b)
second messenger
c)
protein kinase
d)
receptor protein
2.
What determines whether a cell is a target cell for a particular signal molecule?
a)
phosphorylation cascade
b)
cAMP
c)
signal receptors
d)
phosphatase
3.
What determines whether a signal molecule binds on the surface or enters the cell?
a)
size
b)
polarity
c)
ability to cross the membrane
d)
all of these are correct
4.

One very common receptor protein in eukaryotes is the __.

a)

G protein-coupled receptor

b)

cAMP receptor

c)

phosphorylation receptor

d)

ATP receptor

5.

The binding of a ligand to a ligand-gated ion channel can cause the channel to ___.

a)

open

b)

close

c)

both answers can be correct

6.

A cell converting a chemical signal into a cellular response is known as __.

a)

energetics

b)

transduction

c)

ligand response

d)

transformation

7.

After a ligand binds, the intracellular domain of a receptor protein changes _____, initiating transduction of the signal.

a)

color

b)

size

c)

shape

8.

One cellular response to a signal is apoptosis, otherwise known as programmed cell ____.

a)

division

b)

death

c)

growth

d)

reproduction

9.

Which of the following is a chemical message that usually travels through the bloodstream to target cells?

a)

hormone

b)

local regulator

c)

endocrine cell

d)

plasmodesmata

10.

Signal amplification is most often achieved by

a)

an phosphorylation cascade

b)

binding of multiple signals

c)

branching pathways

d)

action of adenylyl cyclase

11.

How bacteria communicated to all "glow" simultaneously--the fluorescent gene expression was regulated by population density.

a)

quorum quotient

b)

quorum sensing

c)

quorum glowing

d)

quorum majority

12.

___________ messengers, such as cyclic AMP (cAMP) are molecules that relay and amplify intracellular signals.

a)

Primary

b)

Secondary

c)

Tertiary

d)

Quaternary

13.

What do secondary messengers, like cAMP, do?

a)

transport a signal through the lipid bilayer

b)

relay & amplify a signal from the outside to the inside of the cell

c)

relay & amplify a message from the inside of the membrane throughout the cytoplasm

d)

dampen the message

14.
What does a protein kinase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme
15.

Any signal molecule that binds to a receptor is called a _______.

a)

Neurotransmitter

b)

Ligand

c)

Receptor

d)

Acetylcholine

16.

ATP each lose TWO phosphates to adenylyl cyclase. After losing two phosphates, ATP becomes _______.

a)

ADP

b)

Adenylyl phosphate

c)

Protein kinase

d)

cyclic AMP (cAMP)

17.

The general name for an enzyme that transfers phosphate groups from ATP to a protein is __________.

a)

protein dehydrogenase

b)

protein kinase

c)

protein phosphatase

d)

peptidase

e)

protein cyclase

18.

Phosphorylation cascades involving a series of protein kinases are useful for cellular signal transduction because __________.

a)

they are species specific.

b)

the number of molecules used is small and fixed.

c)

they always lead to the same cellular response.

d)

they amplify the original signal manyfold.

e)

they counter the harmful effects of phosphatases.

19.

Receptors for signal molecules __________.

a)

all work via protein kinases

b)

are never found in the nucleus of a cell

c)

may be found embedded in the plasma membrane, or found within the cytoplasm or nucleus

d)

all work by opening ion channels

e)

are only found associated with the plasma membrane

20.

What is an organic compound that is made by glands in the body (pituitary, thyroid, etc) that is used in long distance communication between cells?

a)

Hormones

b)

Neurotransmitters

c)

Synapse

d)

Carbohydrates

21.
Maintaining body temperature is an example of a:
a)
negative feedback loop
b)
positive feedback loop
22.
When glucose levels in the blood rise, your brain sends a signal to your pancreas. The pancreas releases insulin, which opens channels in cell membranes to allow glucose to enter the cell, lowering blood sugar levels. 
a)
Positive Feedback Response
b)
Negative Feedback Loop 
23.

An example of a positive feedback loop is ____________.

a)

Childbirth

b)

Blood Pressure regulation

c)

Body Temperature regulation

d)

All of the above

24.
Homeostasis
a)
allows for a wildly fluctuating internal environment
b)
is impossible in vertebrates
c)
is the maintenance of a relatively stable internal environment and often incorporates a form of feedback regulation
d)
is the maintenance of a relatively stable external environment and often incorporates a form of feedback regulation
25.
What type of feedback loop is shown?
a)
Positive
b)
Neutral
c)
Negative
26.
What type of feedback loop is shown?
a)
negative
b)
neutral 
c)
positive
27.
What do second messengers do?
a)
transport a signal through the lipid bilayer
b)
relay a signal from the outside to the inside of the cell
c)
relay message from the inside of the mebrane throughout the cytoplasm
d)
dampen the message
28.
What does a protein kinase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme
29.
Signal amplification is most often achieved by
a)
an enzyme cascade
b)
binding of multiple signals
c)
branching pathways
d)
action of adenylyl cyclase
30.
What do you call it when two neurons communicate through neurotransmitters?
a)
Hormones
b)
Synapse
c)
Cholesterol
d)
Monty
31.
Hormones are used in ____ signaling.
a)
endocrine
b)
juxtacrine
c)
autocrine
d)
paracrine
32.
The 3 steps of signal transduction in order are
a)
reception, transduction, response
b)
response, transduction, reception
c)
reception, response, transduction
d)
transduction, reception, response
33.
This is an example of
a)
paracrine signaling
b)
synaptic signaling
c)
long-distance signaling
d)
all of the above
34.

What is being depicted in the image?

a)

Amplification of the signal molecule

b)

Enzymatic proteins inhibiting process of the signal transduction pathway

c)

Kinase groups adding dimer groups to other enzymes

d)

Diffusion of molecules within the cell due to the signaling molecule

35.

Which type of membrane protein would help intake a message from outside of the cell to inside of the cell?

a)

Receptor Protein

b)

Enzymatic Protein

c)

Channel Protein

d)

Junction Protein

e)

ATP Synthase

36.

Which letter represents the cell membrane?

a)

A

b)

B

c)

C

d)

D

e)

E

37.

Which letter represents the ligand?

a)

A

b)

B

c)

C

d)

D

e)

E

38.

An example of DIRECT (juxtacrine) cell communication is:

a)

White blood cells bumping into each other sharing antigen info

b)

Neurons communicating across a synapse

c)

Hormones traveling through the blood stream to target tissues

39.

Name the structure labeled 'B' (see image)

a)

Post synaptic terminal

b)

Receptor

c)

Ligand

d)

Neurotransmitter

40.

Testosterone does not affect all cells of the body because __________.

a)

testosterone cannot cross the plasma membrane

b)

not all cells have cytoplasmic receptors for testosterone

c)

not all cells in the body have membrane receptors for testosterone

d)

it is a local regulator

e)

it affects only cells that have ion-channel receptors

41.

Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because __________.

a)

only target cells retain the appropriate DNA segments

b)

most cells lack the Y chromosome required

c)

only target cells possess the cytosolic enzymes that transduce the testosterone

d)

only in target cells is testosterone able to initiate the phosphorylation cascade leading to activated transcription factor

e)

intracellular receptors are present only in target cells

42.
Epinephrine (also known as adrenaline or adrenalin) is a hormone and a neurotransmitter. The model for the action of Epinephrine is shown below.
Which of the following molecules act as a second messenger in the cascade by which epinephrine stimulates the activation of the enzyme glycogen phosphorylase?
a)
Adenosine
b)
Adenylyl cyclase
c)
Citric acid
d)
Cyclic AMP
43.

What is the point of a negative feedback loop?

a)

To provide the body with more energy

b)

To provide the body with more food

c)

To make sure the conditions in the body are always changing

d)

To make sure the conditions in the body remain stable

44.
In which phase of mitosis do the sister chromatids line up on the equator of the cell?
a)
Prophase
b)
Metaphase
c)
Anaphase
d)
Telophase
45.
Structure (b) is a ____.
a)
chromosome
b)
chromatid
c)
centromere
46.
Which of the following shows the correct sequence of the cell cycle?
a)
Mitosis-> G1->S->G2->cytokinesis
b)
S->G1-> G2-> mitosis-> cytokinesis
c)
cytokinesis->mitosis->G1->S->G2
d)
 G1->S->G2->mitosis->cytokinesis
47.
The cell carries out normal functions during..
a)
interphase
b)
cytokinesis
c)
mitosis
48.

Uncontrolled cell division which usually leads to tumors and disease is called:

a)

Metaphase

b)

Cytokinesis

c)

Cancer

d)

Diabetes

49.

What word means programmed cell death?

a)

apoptosis

b)

mitosis

c)

Ced-9

d)

bleb

50.

What is the main function of the endocrine system?

a)

It creates chemicals, or hormones, that are sent around the body to maintain homeostasis.

b)

It creates electrical messages that are sent around the body to maintain homeostasis.

c)

It maintains the correct level of oxygen in the body to maintain homeostasis.

d)

It releases waste from the body to maintain homeostasis.