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S2 BIO TEST 3 CH15: Mutations, Pedigree, Karyotypes

Total questions: 63

Worksheet time: 58mins

Name
Class
Date
1.

A karyotype is assembled from the cell of a human donor who has a genetic disorder. Which disorder can be determined by studying the karyotype?

a)

A chromosomal disorder, such as Downs Syndrome

b)

An autosomal dominant disorder such as Huntington’s Disease

c)

A genetic disorder caused by a point mutation, such as sickle cell

d)

An X- Linked genetic disorder, such as colorblindness

2.

A photograph of all of the chromosomes arranged in pairs is called a _____.

a)

karyotype

b)

pedigree

c)

punnett square

d)

venn diagram

3.

A human karyotype has _____.

a)

23 pairs of autosomes and 2 pairs of sex chromosomes

b)

22 pairs of autosomes and 1 pair of sex chromosomes

c)

23 pairs of sex chromosomes and 2 pairs of autosomes

d)

22 pairs of sex chromosomes and 1 pair of autosomes

4.

A _____ shows family relationships and the presence or absence of a trait in each member.

a)

karyotype

b)

pedigree

c)

genome

d)

punnett square

5.

The diagram shows 4 pairs of chromosomes from a human male. Which pair of chromosomes is the sex chromosomes?

a)

Pair 1

b)

Pair 2

c)

Pair 3

d)

Pair 4

6.

Sophie is studying the karyotype of an unknown human donor. She observes that in each of the chromosome pairs, the two chromosomes have the same size and shape. What can Sophie conclude from these observations?

a)

The donor is female

b)

The donor is male

c)

The donor will express only the dominant forms of traits.

d)

The donor will express only the recessive forms of traits.

7.

A genetic disorder is caused by a sex- linked allele on the Y chromosome. How is this disorder inherited?

a)

from father to son

b)

from mother to son

c)

from father to son or daughter

d)

from mother to son or daughter

8.

What is the probability of a couple having a son who is colorblind if the mother is a carrier (XCXc) and the father has normal vision (XcY)? Colorblindness is a recessive trait.

HINT: Do a Punnett Square

a)

25%

b)

50%

c)

75%

d)

100%

9.

Which gender can carry colorblindness if it is an X- linked trait?

a)

females

b)

males

c)

both

d)

neither

10.

In a pedigree, squares represent _____, and circles represent _____.

a)

males; females

b)

males; males

c)

females; females

d)

females; males

11.

If a woman, who carries colorblindness, marries a colorblind man, what is the probability that one of their children will be colorblind?

a)

25%

b)

50%

c)

100%

d)

0%

12.

Based on the pedigree, which sex CANNOT be carriers of colorblindness?

a)

males

b)

females

c)

both

d)

depends on age

13.

What pattern of inheritance is shown in the above pedigree?

a)

sex- linked

b)

incomplete dominance

c)

autosomal dominant

d)

autosomal recessive

14.

What kind of individuals are in II-2, 4, 7; III-2, 7; and IV-3, 6?

a)

carrier female

b)

carrier male

c)

colorblind male

d)

colorblind female

15.

Which individual describes a male with normal vision?

a)

II-6

b)

IV-5

c)

III-5

d)

I-1

16.

A scientist describes the karyotype of a human egg cell as (23, X). The egg cell unites with a sperm cell to form the first cell of a healthy baby boy. What is the karyotype of the sperm cell?

a)

(23, XY)

b)

(23, Y)

c)

(23, XX)

d)

(23, X)

17.

Consider the abbreviated model of meiosis. The end result of meiosis should be the production of four haploid gametes. In this example, an error has taken place. Describe and name this error.

a)

Non-disjunction of sister chromatids during meiosis II. Sister chromatids fail to separate.

b)

Translocation of sister chromatids during meiosis II. One chromatid is translocated into incorrect cell.

c)

Separation mutation during meiosis I. Resulting gametes in meiosis II have incorrect chromosome number at end of meiosis.

d)

Replication error during meiosis I. Results of mutation show during meiosis II as incorrect chromosome number in two gametes.

18.

Digestive enzymes in your stomach and intestines help digest the food you eat. If you are lactose intolerant and cannot digest milk products, it is the result of a mutated message in your

a)

chromosomes

b)

X or Y chromosomes

c)

lysosomes

d)

nucleolus

19.

The genotype of individual 2 could be _____.

a)

ee, only

b)

EE or Ee

c)

Ee, only

d)

EE, only

20.

Is this pedigree showing a dominant or a recessive trait?

a)

recessive

b)

Dominant

c)

none of these

21.

Mustard gas removes guanine from DNA. For developing embryos, exposure to mustard gas can cause serious deformities because guanine _____.

a)

is part of the genetic code.

b)

produces energy for DNA replication.

c)

stores the building blocks of proteins.

d)

causes mutations in DNA.

22.

Sequences for the types of hemoglobin are shown. Sickle-cell anemia is caused by a mutation of one nucleotide in a gene. The type of mutation that causes sickle-cell anemia is known as _____.

a)

an insertion mutation

b)

a frameshift mutation

c)

an inversion mutation

d)

a point mutation

23.

In a species of plant, the sudden appearance of one plant with a different leaf structure would most likely be the result of _____.

a)

chromosomal mutations.

b)

asexual reproduction.

c)

slow environmental changes.

d)

stable gene frequencies.

24.
A chromosome that is not a sex chromosome is known as a(an)
a)
autosome.
b)
karyotype.
c)
pedigree.
d)
chromatid.
25.
The failure of chromosomes to separate during gamete formation in called
a)
nondisjunction
b)
alleles
c)
point mutation
d)
cloning
26.
How many chromosomes are found in each diploid cell of a person with Down syndrome?
a)
47
b)
45
c)
22
d)
24
27.

How can Diagram 1 be identified?

a)

male with Down syndrome

b)

normal male

c)

female with Down syndrome

d)

normal female

28.

How can Diagram 2 be identified?

a)

male with Down syndrome

b)

normal male

c)

female with Down syndrome

d)

normal female

29.

_____ is a technique used to organize DNA fragments in order of size.

a)

Gel Electrophoresis

b)

Restriction enzymes

c)

PCR

d)

Cloning

30.

What pattern of inheritance is shown in the pedigree above?

a)

Autosomal Dominant

b)

Autosomal Recessive

c)

X-link Dominant

d)

X-link Recessive

31.

What is the genotype of individual III-8?

a)

AA

b)

Aa

c)

aa

d)

none of these

32.

Is selective breeding an example of biotechnology? Why or why not?

a)

Yes. Selective breeding involves the application of technology to living things.

b)

Yes. Selective breeding allows a species to incorporate beneficial genes from another species.

c)

No. Selective breeding is a process that occurs naturally among plants or animals.

d)

No. Selective breeding does not involve technical processes that occur in laboratories.

33.

Luther Burbank bred potatoes that combined a variety of useful traits. One of Burbank’s breeding techniques was hybridization. Which cross of potato plants would have been MOST USEFUL for producing a useful strain by hybridization?

a)

a disease-resistant plant crossed with a plant that is not disease resistant

b)

a plant that is not disease resistant crossed with a plant that produces a low volume of food

c)

a disease-resistant plant crossed with a plant that produced a low volume of food

d)

a disease-resistant plant crossed with a plant that produced a high volume of food

34.

Tallness (T) is dominant to shortness (t) in pea plants. Which of the following represents a genotype of a pea plant that is heterozygous for tallness?

a)

Tt

b)

TT

c)

tt

d)

T

35.

The phenotype of an organism _____.

a)

is the physical appearance of a trait.

b)

is used to represent its genetic composition.

c)

cannot be seen.

d)

occurs only in dominant individuals.

36.

The light independent reactions take place in the _____.

a)

stroma

b)

thylakoid

c)

mitochondria

d)

golgi apparatus

37.

During photosynthesis, carbon dioxide and _____ are converted through a series of reactions into two products: high-energy _____ and _____ gas.

a)

water; glucose; oxygen

b)

glucose; water; oxygen

c)

oxygen; water; glucose

d)

water; oxygen; glucose

38.

What are the two processes that keep the carbon cycle going?

a)

photosynthesis and cellular respiration

b)

gametophyte and sporophyte

c)

mitosis and meiosis

d)

none of the above

39.
The purpose of selective breeding is to 
a)
Get bigger animals
b)
get smaller animals
c)
create animals with desirable traits
d)
create animals with bad traits
40.

It is very common for yellow labs to have bad hips. This is because owners want purebred yellow labs who are good hunting dogs. This is an example of

a)

Natural Selection

b)

Inbreeding

c)

Hybridization

d)

Fossil Record

41.
All of the following statements are reasons for selective breeding except:
a)
To produce offspring with desirable characteristics
b)
Farmers increase their profit by improving crops
c)
To improve the quality of food products
d)
To increase migration patterns
42.
The evolution of dogs from wolves is due to:
a)
Natural Selection
b)
Sexual Selection
c)
Artificial Selection
d)
Vestigial Structures
43.
What is inbreeding?
a)
two sets of genes
b)
every trait called alleles
c)
reproduction from mating of two genetically related parents 
d)
combination of parental genes
44.

Crossing a red sweet apple with a large disease resistant apple is an example of ________________.

a)

inbreeding

b)

cloning

c)

natural selection

d)

hybridization

45.

All these birds are finches but they have developed different beaks due to the type of foods available to them, this is because of

a)

Natural Selection

b)

Selective Breeding

46.

What process is being shown in this image?

a)

Selective Breeding

b)

Natural Selection

47.

Another name for Selective Breeding is

a)

Evolution

b)

Natural Selection

c)

Extinction

d)

Artificial Selection

48.

A mutation is defined as:

a)

A change in the cell's structure

b)

Anything that changes in an embryo

c)

Any change in the physical features of a human

d)

A change in the DNA sequence

49.
Where do mutations occur?
a)
DNA and RNA
b)
DNA 
c)
RNA
d)
mRNA and tRNA
50.

A mutation in which only one nucleotide is altered is called a:

a)

Frameshift Mutation

b)

Deletion Mutation

c)

Point Mutation

d)

Insertion Mutation

51.

ATTTGAGCC- Original

ATTGAGCC - Mutated

The example above is an example of a

a)

Insertion

b)

Point mutation

c)

Deletion

d)

Substitution

52.
What mutation has occurred here? 
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift 
53.

Which Karyotype displays a female with Down syndrome?

a)
b)
c)
d)
54.
What pairs with Adenine (A)? 
a)
Guanine (G)
b)
Cytosine (C)
c)
Adenine (A)
d)
Thymine (T)
55.
What pairs with Thymine (T)?
a)
Adenine (A)
b)
Thymine (T)
c)
Guanine (G)
d)
Cytosine (C) 
56.
What pairs with Guanine (G)?
a)
Adenine (A)
b)
Thymine (T)
c)
Cytosine (C)
d)
Guanine (G)
57.
What pairs with Cytosine (C)?
a)
Guanine (G)
b)
Cytosine (C)
c)
Adenine (A)
d)
Thymine
58.
This type of substitution codes for a stop codon
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
59.
If you are missing or have an extra base  at the end of your mutated DNA . What type of mutation occurred?
a)
Substitution
b)
Frameshift
c)
Duplication 
d)
Insertion
60.
A type of substitution in which no  amino acids change is called 
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
61.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
62.
mRNA is read in chunks of three, called...
a)
quadralets
b)
anticodons
c)
codons
d)
capsids
63.
A type of substitution in which one amino acid changes is called 
a)
Nonsense
b)
Missense
c)
Silent
d)
all of the above