WorksheetsColorectal Cancer & Lynch Syndrome
Total questions: 36
Worksheet time: 18mins
A condition where cells grow out of control on the colon and rectum .
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
Inherited condition that increases the risk of certain cancers.
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
Cell growths on the mucosa of the large intestine.
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
A procedure in which a camera is inserted up the anus to view the large intestine.
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
When a sample of tissue is taken from the large intestine and tested for cancer.
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
Symptoms Include: Rectal bleeding, change in bowel habits, cramps, gas, pain, weight loss, fatigue.
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
Symptoms Include: Colon Cancer, Endometrial Cancer, Ovarian Cancer, Urinary cancer, Stomach cancer, Liver cancer, etc.
Colorectal Cancer
Lynch Syndrome
Polyps
Colonoscopy
Biopsy
What causes Colorectal Cancer?
Always begins as a polyp caused by uncontrolled mitosis
Cells invade the muscular layers of LI and invade blood and lymph vessels
Initially caused by a spontaneous mutation in the DNA that causes uncontrolled mitosis
Begins as a heredity autosomal dominant condition that is a mutation in mismatch repair genes (MLH-1, 2, 6, PMS2, and EPCAM).
Occurs when normal copy of gene is "knocked out" leaving individual with no working mismatch repair genes.
What causes Lynch Syndrome?
Always begins as a polyp caused by uncontrolled mitosis
Cells invade the muscular layers of LI and invade blood and lymph vessels
Initially caused by a spontaneous mutation in the DNA that causes uncontrolled mitosis
Begins as a heredity autosomal dominant condition that is a mutation in mismatch repair genes (MLH-1, 2, 6, PMS2, and EPCAM).
Occurs when normal copy of gene is "knocked out" leaving individual with no working mismatch repair genes.
Lynch Syndrome patients inherit an increased risk of cancer. They don't actually inherit cancer.
True
False
Not everyone with Lynch Syndrome will get cancer.
True
False
You are an increased risk of having Lynch Syndrome when . two generations are effected and 1 or more individuals have developed cancer over the age of 50.
True
False
There is no cure for Lynch Syndrome because the mutation is found in every cell in the person's body.
True
False
The mutation(s) inherited by people with Lynch Syndrome impact mismatch repair; meaning that, the DNA is able to better fix DNA mutations.
True
False
The "treatments" for Lynch Syndrome include lifelong screening, surgery to remove cancerous organs, and other forms of cancer treatment.
True
False
A form of tumor testing to identify missing proteins.
Immunohistochemistry
Micro-satellite Instability Testing
Genetic Testing
Cancer Screening
A form of tumor testing to identify unstable sequences of DNA.
Immunohistochemistry
Micro-satellite Instability Testing
Genetic Testing
Family History Evaluation
Blood test to identify mutations in all body cells
Immunohistochemistry
Micro-satellite Instability Testing
Genetic Testing
Family History Evaluation
Interview process where genetic counselors construct a pedigree from information provided by patient.
Immunohistochemistry
Micro-satellite Instability Testing
Genetic Testing
Family History Evaluation
Methods of diagnosing lynch syndrome
Immunohistochemistry
Micro-satellite Instability Testing
Genetic Testing
Family History Evaluation
Removal of entire colon
Total Colectomy
Partial Colectomy
Genetic Testing
Family History Evaluation
Removal of part of colon
Total Colectomy
Partial Colectomy
Polypectomy
Biopsy
Removal of a polyp
Total Colectomy
Partial Colectomy
Polypectomy
Biopsy
Lynch syndrome is an autosomal recessive condition.
True
False
A numerical system that resembles the extent of metastasis
Staging
Chemotherapy/Radiation Therapy
Polyps
Colonoscopy
Biopsy
A numerical system that resembles the extent of metastasis
Staging
Chemotherapy/Radiation Therapy
Polyps
Colonoscopy
Biopsy
Abnormal development of cells within tissues and organs.
Staging
Ostomy Bag
Dysplasia
Colonoscopy
Biopsy
A medical device that allows bodily waste to be rerouted from its usual path because of malfunctioning parts of the digestive system to outside of body.
Staging
Ostomy Bag
Dysplasia
Colonoscopy
Biopsy
Methods of diagnosing colorectal cancer.
Staging
Ostomy Bag
Dysplasia
Colonoscopy
Biopsy
Methods of treating colorectal cancer.
Radiation/Chemotherapy
Ostomy Bag
Total or Partial Colectomy
Colonoscopy
Biopsy
Colorectal cancer can be cured.
True
False
Adenocarcinomas are polyps that originate from cells that lubricate the lumen of large intestine.
True
False
Adenocarcinomas are the LEAST common type of colorectal cancer.
True
False
Lynch Syndrome and Colorectal Cancers originate from mutations in the DNA.
True
False
Both Lynch Syndrome and Colorectal cancer can be cured.
True
False
Both Lynch Syndrome and Colorectal cancer occur in people over the age of 50.
True
False
