wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

5th long exam: antimicrobials 2, anticancer,immunopharma

Total questions: 40

Worksheet time: 42mins

Name
Class
Date
1.

DNA antiviral drug which is the TOPICAL preparation for Herpes simplex virus 1

a)

acyclovir

b)

pencyclovir

c)

gancyclovir

d)

valacyclovir

2.

Antiviral drug of choice for Herpes and Varicella infection

a)

Amantadine

b)

Zidovudine

c)

Acyclovir

d)

Zanamivir

3.

Antiviral drug of choice for CMV retinitis and severe systemic CMV infection

a)

Ganciclovir

b)

aciclovir

c)

zidovudine

d)

Oseltamivir

4.

Used for the treatment and prophylaxis of Influenza A specially in the elderly

a)

zanamivir

b)

oseltamivir

c)

Amantadine

d)

Foscarnet

5.

the drug preparation of Ribavirin for treating Respiratory Syncythial virus (RSV)

a)

intravenous

b)

intrathecal

c)

oral

d)

aerosol spray

6.

—drug of choice for prophylaxis and treatment of AH1N1 pandemic in 2009-2010

a)

Oseltamivir

b)

zanamivir

c)

rimantadine

d)

Tenofovir

7.

anti HIV drugs used to prevent maternal-fetal transmission of HIV

a)

zidovudine

b)

amantadine

c)

tenofovir

d)

Nevirapine

8.

Hepatitis B drugs control the activity of the virus but cannot cure the disease.

a)

true

b)

false

c)

both A and B

d)

none of the above

9.

antiviral drug of choice for the treatment of chronic hepatitis C given as subcutaneous injections

a)

Peginterferon Alfa 2A

b)

Tenofovir

c)

Telbivudine

d)

Entacavir

10.

NNRTI drug that can cross the placenta and blood brain barrier, with good CNS penetration

a)

Nevirapine

b)

Delavirdine

c)

Efavirenz

d)

Enfuvirtide

11.

main sterol component of fungal cell wall that is the target of most antifungal agents

a)

ergosterol

b)

cholesterol

c)

campesterol

d)

sitosterol

12.

antifungal drug of choice for fungal CNS infections because it has best CNS penetration

a)

Amphotericin B

b)

Fluconazole

c)

Clotrimazole

d)

Flucytosine

13.

Drug of choice for for Candidiasis due to Candida albicans; Tinea versicolor due to Malassezia furfur; Diaper rash infected by Candida albicans

a)

Fluconazole

b)

Clotrimazole

c)

Micafungin

d)

Amphotericin B

14.

Azole used to treat blastomycosis, coccidiomycosis, candidiasis but more widely marketed as treatment for seborrheic dermatitis

a)

ketoconazole

b)

itraconazole

c)

voriconazole

d)

Fluconazole

15.

Oral antifungal drug for the treatment of oral thrush that is the drug of choice for children and smaller infants

a)

Fluconazole

b)

nystatin

c)

amphotericin B

d)

Miconazole

16.

Drug of choice for most parasitic worm infestations

a)

Mebendazole

b)

Pyrantel

c)

Praziquantel

d)

all of the above

17.

Drug of choice for onchocerciasis or river blindness that is also used as an anti-scabies agent

a)

Ivermectin

b)

Lindane

c)

Albendazole

d)

Crotramiton

18.

Most toxic antimalarial drug that is used for chloroquine resistant P. falciparum

a)

quinine

b)

Hydroxychloroquine

c)

pyrimethamine

d)

mefloquine

19.

most dreaded complication of chloroquine and hydroxychloroquine

a)

cardiac arrhythmia

b)

blindness

c)

both

d)

generally safe with few side effects

20.

used as a prophylaxis for malaria

a)

quinine

b)

mefloquine

c)

pyrimethamine

d)

hydroxychloroquine

21.

first line DMARD used for the treatment of rheumatoid arthritis

a)

methotrexate

b)

azathioprine

c)

abatacept

d)

cyclosporine

22.

used as an adjunct treatment for the renal diseases of systemic lupus erythematosus and also useful in vasculitis

a)

mycophenolate mofetil

b)

cyclophosphamide

c)

methotrexate

d)

azathioprine

23.

mechanism of glucocorticoids which predisposes chronic users to infection

a)

increases fractional catabolic rate of IgG thus lowering the effective concentration of specific antibodies

b)

depresses T cell and B cell component of immune system

c)

causes myelosuppression and the production of neutrophils and cytotoxic macrophages

d)

all of the above

24.

therapeutic agent of choice for Guillain-Barre syndrome, Kawasaki disease, idiopathic thrombocytopenic purpura based on its pool of donor antibodies

a)

IV immunoglobulins

b)

Rh immune globulin

c)

glucocorticoids

d)

cyclosporine

25.

Rh immunoglobulins are effective in the treatment of Rh hemolytic diseases of the newborn if given

a)

to the Rh (-) mother after birth within 24-72 hours of an Rh (+) baby

b)

to the Rh (-) baby after birth within 24-72 hours of an Rh+ mother

c)

to the Rh (-) mother after birth within 1 week to 1 month of an Rh (+) baby

d)

to the Rh (-) mother after birth within 1 week to 1 year of an Rh (+) baby

26.

alkylating agents except

a)

cyclophosphamide

b)

carmustine

c)

cisplatin

d)

azathioprine

27.

microtubule inhibitor that is a plant alkaloid used in the treatment of acute leukemias, hodgkins lymphomas

a)

vincristine

b)

methotrexate

c)

doxorubicin

d)

Etoposide

28.

topoisomerase inhibitor used in the treatment of lung cancer, testicular cancer, and prostate cancer

a)

Etoposide

b)

Vincristine

c)

Cyclophosphamide

d)

Tamoxifen

29.

Folic acid derivative used to treat toxic effects of methotrexate in cancer therapy

a)

Leucovorin

b)

MESNA

c)

prednisolone

d)

mercaptopurine

30.

antimetabolite anticancer agent used for solid tumors

a)

6-mercaptopurine

b)

methotrexate

c)

5-fluorouracil

d)

cytarabine

31.

monocolonal antibody agent used in breast tumors that overexpresses HER2 protein

a)

Transtuzumab

b)

alemtuzumab

c)

Gemtuzumab

d)

rituxumab

32.

class of alkylating agents used as adjunt treatment in brain tumors

a)

nitrogent mustards

b)

nitrosoureas

c)

methylhydrazines

d)

triazenes

33.

antibiotics used as anticancer agents except

a)

doxorubicin

b)

dactinomycin

c)

bleomycin

d)

streptomycin

34.

most dreaded adverse reaction of antibiotic anticancer therapy Bleomycin

a)

pulmonary toxicity

b)

myelosuppression

c)

cardiac arrythmias

d)

nephrotoxicity

35.

most dreaded adverse effect of doxorubicin

a)

cardiac toxicity

b)

pulmonary toxicity

c)

severe hypersensitivity reaction

d)

steven johnson syndrome

36.

Adverse effect of cyclophosphamide

a)

bladder toxicity

b)

cardiotoxicity

c)

pulmonary fibrosis

d)

alopecia

37.

antiprotozoal drug that can cause disulfiram reaction

a)

metronidazole

b)

mebendazole

c)

clindamycin

d)

ivermectin

38.

antiparasitic drug with neurotoxic effects on Sarcoptes and Pediculus species

a)

Lindane

b)

Permethrin

c)

Crotramiton

d)

Ivermectin

39.

anti-ectoparasite favored for use because of its cooling and anti-itch effect on the skin

a)

permethrin

b)

lindane

c)

crotramiton

d)

sulfur soap

40.

drug of choice for CMV infections but with side effects of thrombocytopenia and granulocytopenia

a)

ganciclovir

b)

aciclovir

c)

tenofovir

d)

amantadine