Worksheets5th long exam: antimicrobials 2, anticancer,immunopharma
Total questions: 40
Worksheet time: 42mins
DNA antiviral drug which is the TOPICAL preparation for Herpes simplex virus 1
acyclovir
pencyclovir
gancyclovir
valacyclovir
Antiviral drug of choice for Herpes and Varicella infection
Amantadine
Zidovudine
Acyclovir
Zanamivir
Antiviral drug of choice for CMV retinitis and severe systemic CMV infection
Ganciclovir
aciclovir
zidovudine
Oseltamivir
Used for the treatment and prophylaxis of Influenza A specially in the elderly
zanamivir
oseltamivir
Amantadine
Foscarnet
the drug preparation of Ribavirin for treating Respiratory Syncythial virus (RSV)
intravenous
intrathecal
oral
aerosol spray
drug of choice for prophylaxis and treatment of AH1N1 pandemic in 2009-2010
Oseltamivir
zanamivir
rimantadine
Tenofovir
anti HIV drugs used to prevent maternal-fetal transmission of HIV
zidovudine
amantadine
tenofovir
Nevirapine
Hepatitis B drugs control the activity of the virus but cannot cure the disease.
true
false
both A and B
none of the above
antiviral drug of choice for the treatment of chronic hepatitis C given as subcutaneous injections
Peginterferon Alfa 2A
Tenofovir
Telbivudine
Entacavir
NNRTI drug that can cross the placenta and blood brain barrier, with good CNS penetration
Nevirapine
Delavirdine
Efavirenz
Enfuvirtide
main sterol component of fungal cell wall that is the target of most antifungal agents
ergosterol
cholesterol
campesterol
sitosterol
antifungal drug of choice for fungal CNS infections because it has best CNS penetration
Amphotericin B
Fluconazole
Clotrimazole
Flucytosine
Drug of choice for for Candidiasis due to Candida albicans; Tinea versicolor due to Malassezia furfur; Diaper rash infected by Candida albicans
Fluconazole
Clotrimazole
Micafungin
Amphotericin B
Azole used to treat blastomycosis, coccidiomycosis, candidiasis but more widely marketed as treatment for seborrheic dermatitis
ketoconazole
itraconazole
voriconazole
Fluconazole
Oral antifungal drug for the treatment of oral thrush that is the drug of choice for children and smaller infants
Fluconazole
nystatin
amphotericin B
Miconazole
Drug of choice for most parasitic worm infestations
Mebendazole
Pyrantel
Praziquantel
all of the above
Drug of choice for onchocerciasis or river blindness that is also used as an anti-scabies agent
Ivermectin
Lindane
Albendazole
Crotramiton
Most toxic antimalarial drug that is used for chloroquine resistant P. falciparum
quinine
Hydroxychloroquine
pyrimethamine
mefloquine
most dreaded complication of chloroquine and hydroxychloroquine
cardiac arrhythmia
blindness
both
generally safe with few side effects
used as a prophylaxis for malaria
quinine
mefloquine
pyrimethamine
hydroxychloroquine
first line DMARD used for the treatment of rheumatoid arthritis
methotrexate
azathioprine
abatacept
cyclosporine
used as an adjunct treatment for the renal diseases of systemic lupus erythematosus and also useful in vasculitis
mycophenolate mofetil
cyclophosphamide
methotrexate
azathioprine
mechanism of glucocorticoids which predisposes chronic users to infection
increases fractional catabolic rate of IgG thus lowering the effective concentration of specific antibodies
depresses T cell and B cell component of immune system
causes myelosuppression and the production of neutrophils and cytotoxic macrophages
all of the above
therapeutic agent of choice for Guillain-Barre syndrome, Kawasaki disease, idiopathic thrombocytopenic purpura based on its pool of donor antibodies
IV immunoglobulins
Rh immune globulin
glucocorticoids
cyclosporine
Rh immunoglobulins are effective in the treatment of Rh hemolytic diseases of the newborn if given
to the Rh (-) mother after birth within 24-72 hours of an Rh (+) baby
to the Rh (-) baby after birth within 24-72 hours of an Rh+ mother
to the Rh (-) mother after birth within 1 week to 1 month of an Rh (+) baby
to the Rh (-) mother after birth within 1 week to 1 year of an Rh (+) baby
alkylating agents except
cyclophosphamide
carmustine
cisplatin
azathioprine
microtubule inhibitor that is a plant alkaloid used in the treatment of acute leukemias, hodgkins lymphomas
vincristine
methotrexate
doxorubicin
Etoposide
topoisomerase inhibitor used in the treatment of lung cancer, testicular cancer, and prostate cancer
Etoposide
Vincristine
Cyclophosphamide
Tamoxifen
Folic acid derivative used to treat toxic effects of methotrexate in cancer therapy
Leucovorin
MESNA
prednisolone
mercaptopurine
antimetabolite anticancer agent used for solid tumors
6-mercaptopurine
methotrexate
5-fluorouracil
cytarabine
monocolonal antibody agent used in breast tumors that overexpresses HER2 protein
Transtuzumab
alemtuzumab
Gemtuzumab
rituxumab
class of alkylating agents used as adjunt treatment in brain tumors
nitrogent mustards
nitrosoureas
methylhydrazines
triazenes
antibiotics used as anticancer agents except
doxorubicin
dactinomycin
bleomycin
streptomycin
most dreaded adverse reaction of antibiotic anticancer therapy Bleomycin
pulmonary toxicity
myelosuppression
cardiac arrythmias
nephrotoxicity
most dreaded adverse effect of doxorubicin
cardiac toxicity
pulmonary toxicity
severe hypersensitivity reaction
steven johnson syndrome
Adverse effect of cyclophosphamide
bladder toxicity
cardiotoxicity
pulmonary fibrosis
alopecia
antiprotozoal drug that can cause disulfiram reaction
metronidazole
mebendazole
clindamycin
ivermectin
antiparasitic drug with neurotoxic effects on Sarcoptes and Pediculus species
Lindane
Permethrin
Crotramiton
Ivermectin
anti-ectoparasite favored for use because of its cooling and anti-itch effect on the skin
permethrin
lindane
crotramiton
sulfur soap
drug of choice for CMV infections but with side effects of thrombocytopenia and granulocytopenia
ganciclovir
aciclovir
tenofovir
amantadine
