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AP Biology unit 4 review

Total questions: 47

Worksheet time: 2hrs 54mins

Name
Class
Date
1.
Which of the following would be an example of paracrine signaling in animals?
a)
neurotransmitter acetylcholine
b)
hormone epinephrine
c)
neurotransmitter norepinephrine
d)
growth factor
2.
A signal molecule that binds to a plasma-membrane protein is a
a)

ligand

b)

second messenger

c)

protein kinase

d)

receptor protein

3.
What is a G protein?
a)

specific type of membrane-receptor protein

b)

protein on the cytoplasmic side of a membrane

c)

membrane-bound enzyme

d)

relay protein

4.
Which of the following can activate a protein by transferring a phosphate group to it?
a)

cAMP

b)

G Protein

c)

protein kinase

d)

protein phosphatase

5.
What do second messengers do?
a)

transport a signal through the lipid bilayer

b)

relay a signal from the outside to the inside of the cell

c)

relay message from the inside of the mebrane throughout the cytoplasm

d)

dampen the message

6.
What is a function of the second messenger IP3?
a)

bind to and activate protein kinase A

b)

activate transcription factors

c)

convert ATP to cAMP

d)

bind to and open ligand-gated channels

7.
Which of the following is involved in many human medicines for disease?
a)

cAMP

b)

Calcium concentration

c)

G-protein pathways

d)

receptor tyrosine kinases

8.
Signal amplification is most often achieved by
a)

an enzyme cascade

b)

binding of multiple signals

c)

branching pathways

d)

action of adenylyl cyclase

9.
What does a protein kinase do?
a)

removes phosphates

b)

transfers phosphates from ATP to proteins

c)

activates an enzyme

10.
What does a protein phosphatase do?
a)

removes phosphates

b)

transfers phosphates from ATP to proteins

c)

activates an enzyme with a signal molecule

11.
What is a phosphorylation cascade?
a)
travelling of hormones through the air
b)
travelling of hormones through the blood
c)
the removal of a phosphate
d)
a series of molecules that get phosphorylated
12.
What determines whether a cell is a target cell for a particular signal molecule?
a)

phosphorylation cascade

b)

cAMP

c)

signal receptors

d)

phosphatase

13.
What determines whether a signal molecule binds on the surface or enters the cell?
a)
size
b)
polarity
c)
ability to cross the membrane
d)
all of these are correct
14.
Which of the following is a chemical message that usually travels through the bloodstream to target cells?
a)

hormone

b)

local regulator

c)

endocrine cell

15.
What do you call it when two neurons communicate through neurotransmitters?
a)
Hormones
b)
Synapse
c)
Cholesterol
d)
Monty
16.
What is an organic compound that is made by glands in the body (pituitary, thyroid, etc) that is used in long distance communication between cells?
a)
Hormones
b)
Neurotransmitters
c)
Synapse
d)
Carbohydrates
17.

Plasmodesmata in plant cells are analogous to what structure in animal cells?

a)

Tight junctions

b)

Gap junctions

c)

Adhesion junctions

d)

Vacuoles

18.

Urine is confined to the human bladder in part due to the structure of junctions that connect the cells lining the bladder. These junctions form a barrier that prevents the exchange of ions and solutes between the blood and urine. What is the likely identity of these junctions?

a)

Gap junctions

b)

Tight junctions

c)

Adhering junctions

d)

Plasmodesmata

19.

Which of these correctly matches the cellular junction with its function?

a)

Gap junctions prevent the flow of ions and water from one part of the body to another

b)

Adhering junctions are branched network of proteins that are impermeable to fluids

c)

Gap junctions are connections that directly connect the cytoplasm of two cells

d)

Tight junctions are random, spot attachments between cells that prevent tearing of tissue

20.
What type of transmembrane receptor is being shown?
a)
 tyrosine kinase receptor
b)
G-protein receptor
c)
gated ion channel
21.
The 3 steps of signal transduction in order are
a)
reception, transduction, response
b)
response, transduction, reception
c)
reception, response, transduction
d)
transduction, reception, response
22.
What type of transmembrane receptor is being shown?
a)
G-protein receptor
b)
tyrosine kinase receptor
c)
gated ion channel
23.
What type of transmembrane receptor is being shown?
a)
gated ion channel
b)
G-protein receptor
c)
tyrosine kinase receptor
24.
Which of the following correctly describes the reception stage of this signal transduction pathway?
a)
epinephrine binds to a g-protein coupled receptor protein present in the cell membrane
b)
the g protein changes shape, is activated, activates adenyl cyclase, which activates cAMP, which activates protein kinases
c)
protein kinases phosphoylate molecules
d)
glycogen synthesis is inhibited and glycogen breakdown is promoted
25.

Neurons release acetylcholine (ACh) into the gap between the nerve cell and a muscle cell. ACh then binds to receptors in the muscle cell membrane, resulting in the release of Ca2+ from the smooth ER

a)

autocrine signalling

b)

juxtacrine signalling

c)

paracrine signalling

d)

endocrine signalling

26.

Glucagon, released from the pancreas, attaches to receptors in the liver, resulting in the breakdown of glycogen stores and an increase in blood sugar

a)

autocrine signalling

b)

juxtacrine signalling

c)

paracrine signalling

d)

endocrine signalling

27.
1.  Each of the following numbered processes are involved in signal transduction pathways:  
 I.  Response
 
II.  Amplification
 
 III.  Reception
 
IV.  Transduction
Which of the following represents the sequence of events in a typical signal transduction pathway?
a)
I, II, III, IV
b)
III, I, IV, II
c)
II, IV, I, III
d)
III, IV, II, I
28.
What type of feedback loop is shown?
a)
Positive
b)
Neutral
c)
Negative
29.
When glucose levels in the blood rise, your brain sends a signal to your pancreas. The pancreas releases insulin, which opens channels in cell membranes to allow glucose to enter the cell, lowering blood sugar levels. 
a)
Positive Feedback Response
b)
Negative Feedback Loop 
30.
What type of feedback loop is shown?
a)
negative
b)
neutral 
c)
positive
31.
During which phase of the cell cycle does the cell spend the most time?
a)
Mitosis
b)
Cytokinesis
c)
Interphase
32.
During which part of the cell cycle does the cell divide?
a)
Interphase
b)
Mitosis
c)
S phase
33.
During which part of the cell cycle is DNA copied?
a)
Mitosis
b)
Cytokinesis
c)
S phase
34.
Which of these lists presents the stages of the cell cycle in the correct order?
a)
interphase, mitosis, cytokinesis
b)
cytokinesis, mitosis, interphase
c)
mitosis, interphase, cytokinesis
d)
interphase, cytokinesis, mitosis
35.

How is cancer related to cell division?

a)

Mutations can cause uncontrolled cell division which causes cancerous cells to spread rapidly and take nutrients from healthy cells.

b)

Cancer stops cell division from happening.

c)

Cell division causes viruses that spread around the body and cause cancer.

d)

Cancer is not related to cell division.

36.

The G1, S, and G2 are parts of which phase of the cell cycle?

a)

Prophase

b)

Interphase

c)

Telophase

d)

Anaphase

37.

What is a difference between mitosis and meiosis? Mark ALL that apply!

a)

Mitosis occurs in the cytoplasm and Meiosis occurs in the nucleus.

b)

Mitosis results in diploid (2n) daughter cells and Meiosis results in haploid (n) daughter cells.

c)

Mitosis results in 2 daughter cells and Meiosis results in 4 daughter cells.

d)

Mitosis makes somatic (body) cells and Meiosis makes gametes (egg and sperm cells).

38.

During prophase

a)

DNA lines up in the middle of the cell and DNA attaches to spindle fibers

b)

centrioles and spindle fibers appear

c)

2 new identical cells are created

d)

DNA gets copied

39.

During metaphase

a)

DNA lines up in the middle of the cell and DNA attaches to spindle fibers

b)

centrioles and spindle fibers appear

c)

2 new identical cells are created

d)

DNA gets copied

40.

During anaphase

a)

DNA lines up in the middle of the cell and DNA attaches to spindle fibers

b)

centrioles and spindle fibers appear

c)

Each DNA gets pull to the opposite sides of the cell

d)

DNA gets copied

41.

During telophase

a)

DNA lines up in the middle of the cell and DNA attaches to spindle fibers

b)

centrioles and spindle fibers appear

c)

Each DNA gets pull to the opposite sides of the cell

d)

2 new nuclei form

42.

During cytokinesis

a)

DNA lines up in the middle of the cell and DNA attaches to spindle fibers

b)

Cell membrane pinches to make 2 new identical daughter cells

c)

Each DNA gets pull to the opposite sides of the cell

d)

2 new nuclei form

43.

Enzyme to which cyclin binds during interphase and mitosis, triggering and controlling activities during the cell cycle.

a)

Cyclin

b)

Carcinogen

c)

Cyclin - dependent kinase

d)

Cancer

44.

One of the specific proteins that regulate the cell cycle.

a)

Cancer

b)

Cyclin

c)

Carcinogen

d)

Apoptosis

45.

___________ is programmed cell death.

a)

Mitosis

b)

Apoptosis

c)

Meiosis

d)

Interphase

46.

Changing the time you eat breakfast will have no effect on your daily mood. This statement is an example of a ___.

a)

Null Hypothesis

b)

Alternative Hypothesis

c)

Generalization

d)

Assumption

47.

Which is NOT an example of an alternative hypothesis?

a)

Eating breakfast 30 minutes earlier will improve your mood for the day.

b)

Increasing the temperature of water will increase the growth rate of bacteria.

c)

Temperature of water has no effect on the speed of swimmers.

d)

Tylenol will allow for relief when consumed by patients with headaches.