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Worksheets

DNA, Proteins, Mutations

Total questions: 27

Worksheet time: 1hrs 26mins

Name
Class
Date
1.

In DNA molecules, which nitrogenous base is complementary to Cytosine?

a)

Uracil

b)

Guanine

c)

Adenine

d)

Thymine

2.

This is the primary enzyme responsible for DNA replication; it "reads" DNA strands and attaches complementary bases in the correct sequence.

a)

DNA Polymerase III

b)

DNA Polymerase I

c)

DNA Helicase

d)

DNA Ligase

3.

Which biomolecule is primarily responsible for the storage of the genetic information necessary for an organism to perform all of its functions?

a)

mRNA

b)

Proteins

c)

rRNA

d)

DNA

4.

DNA replication produces two new DNA molecules, each of which contains one old strand and one newly-synthesized strand. For this reason, we say that DNA replication is:

a)

Conservative

b)

Semi-conservative

c)

Destructive

d)

Creative

5.

These molecules are the "building blocks" of DNA and RNA:

a)

Nucleotides

b)

Amino Acids

c)

Nucleic Acids

d)

Proteins

6.

This enzyme is responsible for unwinding/"unzipping" the DNA double helix during the first step of DNA replication:

a)

DNA Ligase

b)

DNA Zipperase

c)

DNA Polymerase III

d)

DNA Helicase

7.

The three components of a nucleotide are a pentose sugar (either deoxyribose or ribose), a phosphate group, and a_____________________

a)

Nitrogenous base

b)

Genetic base

c)

Hydrogenous base

d)

Random chemical

8.

The overall structure of a DNA molecule can be described as a:

a)

Helix

b)

Double Helix

c)

Ribbon

d)

Single strand

9.

The small segments of DNA that DNA Polymerase III creates on the lagging strand during replication are called:

a)

Nucletotides

b)

RNA primers

c)

Okazaki fragments

d)

Polypeptides

10.

This is the enzyme that finishes the process of DNA replication by connecting the many Okazaki fragments of the lagging strand:

a)

DNA Polymerase III

b)

DNA Polymerase I

c)

DNA Ligase

d)

Primase

11.

During the finishing stage of DNA replication, this enzyme is responsible for replacing the RNA primers with DNA nucleotides.

a)

Primase

b)

DNA Polymerase III

c)

DNA Polymerase I

d)

DNA Ligase

12.

Please select the correct complement for this DNA sequence: AAT CAT GTA CGC GGG

a)

AAT CAT GTA CGC GGG

b)

TTA GTA CAT GCG CCC

c)

GGG CGC ATG TAC TAA

d)

TAA TAC ATG CGC GGG

13.

This is the type of bond that holds together the complementary bases of the two strands of the DNA double helix :

a)

Covalent bond

b)

Ionic bond

c)

Hydrogen bond

d)

Chemical bond

14.

True or False: The full names of the DNA nucleotides are Adenine, Cytosine, Thymine, and Guanine

a)

True

b)

False

15.

The end of a DNA strand that has a phosphate group is called the:

a)

5' end

b)

3' end

16.

The end of a DNA strand that has a deoxyribose sugar is called the:

a)

5' end

b)

3' end

17.

Which of these is a correct description of the steps and enzymes involved in DNA replication?

a)

Unwinding by DNA Helicase, placement of RNA primers by Primase, synthesis of new strands by DNA Polymerase III, finishing stage by DNA Polymerase I and DNA Ligase.

b)

Unwinding by DNA Polymerase I, placement of RNA primers by DNA Ligase, synthesis of new strands by DNA Polymerase III, finishing stage by DNA Helicase and DNA Ligase.

c)

Unwinding by DNA Helicase, placement of RNA primers by DNA Polymerase I, synthesis of new strands by DNA Ligase, finishing stage by DNA Polymerase III and Primase.

18.

The nitrogenous base that is only found in RNA and that replaces Thymine is called:

a)

Adenine

b)

Cytosine

c)

Thymosine

d)

Uracil

19.

This is the type of RNA that carries the genetic instructions encoded by DNA out of the nucleus to a ribosome where it can be converted into a protein:

a)

tRNA

b)

rRNA

c)

mRNA

d)

siRNA

20.

This is the second stage of protein synthesis; in this stage, a ribosome reads mRNA codons and assists in assembling a chain of amino acids that will become a protein:

a)

Transcription

b)

Translation

c)

Replication

d)

Proteination

21.

This is a specific sequence within an organism's DNA that encodes a specific protein; it is the basic unit of genetic information.

a)

Gene

b)

Exon

c)

Codon

d)

Transcript

22.

This type of RNA molecule carries amino acids to the ribosome during translation; when its anticodon binds to a matching codon, the amino acid it carries is added to the growing protein.

a)

mRNA

b)

tRNA

c)

rRNA

d)

siRNA

23.

This type of molecule is the basic building block of proteins. Each different type of this molecule has a unique functional group called an R-group or a side chain.

a)

Amino acid

b)

Nucleotide

c)

Uracil

d)

Monomer

24.

This is the first stage of protein synthesis; it occurs in the nucleus, and involves the transfer of genetic information from DNA to RNA:

a)

Transcription

b)

Translation

c)

Genetic Transfer

d)

Proteination

25.

These are the 3-nucleotide units within mRNA transcripts that each code for a specific amino acid.

a)

Codons

b)

Anticodons

c)

Genes

d)

Amino units

26.

Using the genetic code table (you may need to open your notes to find a bigger version if it does not load right in this quiz), translate this mRNA codon sequence into an amino acid sequence


AUG GCG UUU AAG UGA

a)

Met - Ala - Phe - Lys - STOP

b)

Met - Gly - Lys - Ser - STOP

c)

Lys - Phe - Arg - Met - STOP

d)

STOP - Leu - Ile - Thr - Met

27.

Unmutated sequence: CGC AAA TTC AGG


Mutated sequence: CGC TAA ATT CAG G


What type of mutation has occurred here?

a)

1 base insertion, frameshift

b)

1 base deletion, frameshift

c)

1 base substitution, synonymous

d)

1 base substitution, nonsynonymous