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BMS291 Musculoskeletal Disorders

Total questions: 30

Worksheet time: 3hrs 30mins

Name
Class
Date
1.

A sprain is an injury to a ligament.

a)

True

b)

False

2.

A sprain is an injury to a ligament.

a)

True

b)

False

3.

A dislocation is defined as the displacement of one or more bones at a joint

a)

True

b)

False

4.

What is the difference between a closed and an open fracture?

4 lines
5.

What is the difference between a incomplete and a complete fracture?

4 lines
6.

Which part of the bone fracture repair process does the following refer to?

Osteoblasts continue to lay down bone to help strengthen the structure. Osteoclasts begin to remove excess bone and reshape the structure until it resembles its former shape. Remodelling may take several years.

a)

Hematoma Formation

b)

Fibrocartilaginous Callus Formation

c)

Bony Callus Formation

d)

Bone Remodelling

7.

Which part of the bone fracture repair process does the following refer to?

Granulation tissue is formed by fibroblasts depositing collagen, chondroblasts depositing cartilage and osteobalsts depositing osteiod. This "soft callus" takes 1 week to form.

a)

Hematoma Formation

b)

Fibrocartilaginous Callus Formation

c)

Bony Callus Formation

d)

Bone Remodelling

8.

Which part of the bone fracture repair process does the following refer to?

This process takes place over the next month where the soft callus is "mineralised" by the addition of calcium and mineral salts. When this process is finished the tissue is called "hard callus".

a)

Hematoma Formation

b)

Fibrocartilaginous Callus Formation

c)

Bony Callus Formation

d)

Bone Remodelling

9.

Which part of the bone fracture repair process does the following refer to?

This stage begins immediately following the fracture. The blood vessels supplying the bone and periosteum are ruptured during the fracture, causing a hematoma to form around the fracture site. The hematoma clots, and forms the temporary frame for subsequent healing. The injury to bone results in the secretion of pro-inflammatory cytokines . These cytokines attract macrophages, monocytes, and lymphocytes. These cells act together to remove damaged, necrotic tissue and secrete cytokines like vascular endothelial growth factor (VEGF) to stimulate healing at the site.

a)

Hematoma Formation

b)

Fibrocartilaginous Callus Formation

c)

Bony Callus Formation

d)

Bone Remodelling

10.

Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.

a)

True

b)

False

11.

The disruption of skeletal muscle integrity leads to the direct release of intracellular muscle components, including myoglobin, creatine kinase (CK), aldolase, and lactate dehydrogenase, as well as electrolytes, into the bloodstream and extracellular space.

a)

Rhabdomyolysis

b)

Rheumatoid Arthritis

12.

Name one physical and non-physical cause of rhabdomyolysis from the reading provided.

4 lines
13.

This terms refers to the physical responses to severe crushing injury of muscle tissue involving especially shock and partial or complete renal failure.

a)

crush syndrome

b)

rhabdomyolysis

c)

oedema

14.

an infectious usually painful inflammatory disease of bone often of bacterial origin that may result in the death of bone tissue

a)

crush syndrome

b)

rhabdomyolysis

c)

osteomyelitis

15.

In this disorder there is a loss of blood supply to the bone and without blood, the bone tissue dies.

a)

Osteonecrosis

b)

Osteomyelitis

16.

osteoarthritis is a disorder where chondrocytes, the cells that create and maintain the (a)   in the joint, start releasing inflammatory mediators.

17.

Treatment of osteoarthritis is based on

a)

curing the condition.

b)

managing the symptoms.

18.

Rheumatoid arthritis is a disorder where a person produces (a)   . This leads to immuncomplexes which ultimately elicits the inflammatory response in the joint.

19.

Treatment of rheumatoid arthritis is based on

a)

curing the condition.

b)

managing the symptoms.

20.

The basic mechanism of action of Disease-Modifying Anti-rheumatic Drugs (DMARs) is to

a)

increase mitosis of white blood cells and to amplify the immune response.

b)

reduce mitosis of white blood cells and to dampen the immune response.

21.

___________ is a chronic inflammatory disease that affects the spine and sacroiliac joints and often other joints (as of the shoulder) and that is marked by pain and stiffness.

a)

rheumatoid arthritis

b)

ankylosing spondylitis

22.

Ankylosing spondylitis can lead to

a)

fusion of the vertebrae

b)

narrow and inflamed inter-vertebral discs

c)

an elongated spine

23.

This disease is marked by a painful inflammation of the joints, deposits of urates in and around the joints, and usually an excessive amount of uric acid in the blood.

a)

gout

b)

osteoarthritis

24.

A joint with gout has

a)

tophi

b)

uric acid crystals

c)

a swollen synovial membrane

d)

a shrunken appearance

25.

This is a disease characterized by progressive wasting of muscles.

a)

muscular dystrophy

b)

rhabdomyolysis

26.

Describe the pathophysiology of rhabdomyolysis .

4 lines
27.

Describe the pathophysiology of osteomyelitis.

4 lines
28.

Describe the pathophysiology of osteonecrosis.

4 lines
29.

Describe the pathophysiology of rheumatoid arthritis.

4 lines
30.

Describe the pathophysiology of osteoarthritis.

4 lines