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WorksheetsBMS291 Musculoskeletal Disorders
Total questions: 30
Worksheet time: 3hrs 30mins
A sprain is an injury to a ligament.
True
False
A sprain is an injury to a ligament.
True
False
A dislocation is defined as the displacement of one or more bones at a joint
True
False
What is the difference between a closed and an open fracture?
What is the difference between a incomplete and a complete fracture?
Which part of the bone fracture repair process does the following refer to?
Osteoblasts continue to lay down bone to help strengthen the structure. Osteoclasts begin to remove excess bone and reshape the structure until it resembles its former shape. Remodelling may take several years.
Hematoma Formation
Fibrocartilaginous Callus Formation
Bony Callus Formation
Bone Remodelling
Which part of the bone fracture repair process does the following refer to?
Granulation tissue is formed by fibroblasts depositing collagen, chondroblasts depositing cartilage and osteobalsts depositing osteiod. This "soft callus" takes 1 week to form.
Hematoma Formation
Fibrocartilaginous Callus Formation
Bony Callus Formation
Bone Remodelling
Which part of the bone fracture repair process does the following refer to?
This process takes place over the next month where the soft callus is "mineralised" by the addition of calcium and mineral salts. When this process is finished the tissue is called "hard callus".
Hematoma Formation
Fibrocartilaginous Callus Formation
Bony Callus Formation
Bone Remodelling
Which part of the bone fracture repair process does the following refer to?
This stage begins immediately following the fracture. The blood vessels supplying the bone and periosteum are ruptured during the fracture, causing a hematoma to form around the fracture site. The hematoma clots, and forms the temporary frame for subsequent healing. The injury to bone results in the secretion of pro-inflammatory cytokines . These cytokines attract macrophages, monocytes, and lymphocytes. These cells act together to remove damaged, necrotic tissue and secrete cytokines like vascular endothelial growth factor (VEGF) to stimulate healing at the site.
Hematoma Formation
Fibrocartilaginous Callus Formation
Bony Callus Formation
Bone Remodelling
Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.
True
False
The disruption of skeletal muscle integrity leads to the direct release of intracellular muscle components, including myoglobin, creatine kinase (CK), aldolase, and lactate dehydrogenase, as well as electrolytes, into the bloodstream and extracellular space.
Rhabdomyolysis
Rheumatoid Arthritis
Name one physical and non-physical cause of rhabdomyolysis from the reading provided.
This terms refers to the physical responses to severe crushing injury of muscle tissue involving especially shock and partial or complete renal failure.
crush syndrome
rhabdomyolysis
oedema
an infectious usually painful inflammatory disease of bone often of bacterial origin that may result in the death of bone tissue
crush syndrome
rhabdomyolysis
osteomyelitis
In this disorder there is a loss of blood supply to the bone and without blood, the bone tissue dies.
Osteonecrosis
Osteomyelitis
osteoarthritis is a disorder where chondrocytes, the cells that create and maintain the (a) in the joint, start releasing inflammatory mediators.
Treatment of osteoarthritis is based on
curing the condition.
managing the symptoms.
Rheumatoid arthritis is a disorder where a person produces (a) . This leads to immuncomplexes which ultimately elicits the inflammatory response in the joint.
Treatment of rheumatoid arthritis is based on
curing the condition.
managing the symptoms.
The basic mechanism of action of Disease-Modifying Anti-rheumatic Drugs (DMARs) is to
increase mitosis of white blood cells and to amplify the immune response.
reduce mitosis of white blood cells and to dampen the immune response.
___________ is a chronic inflammatory disease that affects the spine and sacroiliac joints and often other joints (as of the shoulder) and that is marked by pain and stiffness.
rheumatoid arthritis
ankylosing spondylitis
Ankylosing spondylitis can lead to
fusion of the vertebrae
narrow and inflamed inter-vertebral discs
an elongated spine
This disease is marked by a painful inflammation of the joints, deposits of urates in and around the joints, and usually an excessive amount of uric acid in the blood.
gout
osteoarthritis
A joint with gout has
tophi
uric acid crystals
a swollen synovial membrane
a shrunken appearance
This is a disease characterized by progressive wasting of muscles.
muscular dystrophy
rhabdomyolysis
Describe the pathophysiology of rhabdomyolysis .
Describe the pathophysiology of osteomyelitis.
Describe the pathophysiology of osteonecrosis.
Describe the pathophysiology of rheumatoid arthritis.
Describe the pathophysiology of osteoarthritis.
