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Pathlogy Quiz

Total questions: 75

Worksheet time: 38mins

Name
Class
Date
1.
Cause for caseous necrosis in TB
a)
High lipid content
b)
mycolic acid
c)
Hydropic changes
d)
Hydrolytic enzymes
2.
Increase in size of cell is referred to as
a)
hyperplasia
b)
metaplasia
c)
hypertrophy
d)
atrophy
3.
Lympho-hematogenous spread of Tuberculosis is referred to as
a)
FiBrocaseous Tuberculosis
b)
Caitatory Tuberculosis
c)
Primary Tuberculosis
d)
Miliarty Tuberculosis
4.
Which of the following statement is true
a)
Craniotabes refers to hardening and thickening of skull
b)
Rachitic rosary is a deformity of chest due to cartilaginous overgrowth at costochondral junction
c)
Pigeon-chest deformity is posterior protrusion of sternum due to action of respiratory muscles
d)
Most commonly affected bones in osteomalacia are humerus and tibia
5.
Langhans giant cell is seen in
a)
Tuberculosis
b)
Xanthoma
c)
Hodgkin’s lymphoma
d)
Syphilis
6.
Pellagra is seen in deficiency of which vitamin
a)
Vitamin B1
b)
Vitamin B2
c)
Vitamin B6
d)
Vitamin B3
7.
Which types of ulcer are seen in intestine( with respect to long axis) in enteric fever
a)
Diagonal
b)
Transverse
c)
Longitudnal
d)
None of the above
8.
Reversible change in which one adult cell type (epithelial or mesenchymal) is replaced by another adult cell type is referred to as
a)
hyperplasia
b)
metaplasia
c)
hypertrophy
d)
atrophy
9.
What does paraneoplastic syndrome refer to?
a)
The effects of substances such as hormones secreted by the tumour cells
b)
 Severe weight loss and cachexia associated with advanced cancer
c)
The decreased resistance to infection resulting from malignant tumours
d)
The effects of multiple metastatic tumours
10.
Scarring of hepatic parenchyma as a result of gummas is termed as
a)
Fatty liver
b)
Hepar lobatum
c)
Hepatic adenoma
d)
Hepatocellular carcinoma
11.
Deficiency of vitamin B2 leads to
a)
Pellagra
b)
Beri-Beri
c)
Ariboflavinosis
d)
Neural tube defect
12.
Granuloma is a microscopic aggregation of
a)
Cytotoxic T-cells
b)
NK-cell
c)
neutrophils
d)
Epithelioid cells
13.
Histopathology of chronic hepatitis shows
a)
Ballooning degeneration
b)
Councilman bodies
c)
Interface hepatitis
d)
All of the above
14.
Which culture is most diagnostic in first week of typhoid fever
a)
Urine
b)
Blood
c)
Faeces
d)
Throat
15.
Most common site for secondary Tuberculosis is
a)
Lower lobe of the lung
b)
Middle lobe of lung
c)
Apex of lung
d)
None of the above
16.
Vanillyl mandelic acid (VMA) is excreted in urine in which condition
a)
Alkaptonuria
b)
Phenylketonuria
c)
Pheochromocytoma
d)
Diabetic ketoacidosis
17.
Enlargement of the uterus during pregnancy is an example of
a)
hypertrophy
b)
hyperplasia
c)
both of the above
d)
none of the above
18.
Most common route of transmission in TB is
a)
Inhalation
b)
Ingestion
c)
vertical transmission
d)
none of the above
19.
Chromosomal abnormalities are more commonly seen in
a)
normal cell
b)
malignant cell
c)
necrotic cell
d)
benign cell
20.
Calcitonin is a marker of
a)
Prostate cancer
b)
Medullary carcinoma thyroid
c)
Pheochromocytoma
d)
Pancreatic cancer
21.
Two most common sites for blood-borne metastasis are
a)
lung and pancreas
b)
liver and spleen
c)
lung and liver
d)
none of the above
22.
Lepromin test is negative in
a)
Lepromatous leprosy
b)
Tuberculoid leprosy
c)
Both of the above
d)
None of the above
23.
Characteristic of Tuberculosis is
a)
Non Caseating granuloma
b)
Gumma
c)
Caseating granuloma
d)
None of the above
24.
Common childhood tumors include all except
a)
Neuroblastoma
b)
Nephroblastoma
c)
Retinoblastoma
d)
Hepatocellular carcinoma
25.
A chronic alcoholic has an elevated serum α-fetoprotein levels. Which of the following neoplasms is most likely?
a)
  Prostatic adenocarcinoma
b)
  Multiple myeloma
c)
Hepatocellular carcinoma
d)
Glioblastoma multiforme
26.
Acrodermatitis enteropathica is seen in deficiency of which mineral
a)
copper
b)
calcium
c)
Iron
d)
Zinc
27.
Sensory disturbance is more commonly seen in
a)
Lepromatous leprosy
b)
Tuberculoid leprosy
c)
Both of the above
d)
None of the above
28.
Exfoliative cytology is useful in diagnosis of
a)
<br />Carcinoma stomach<br />
b)
Carcinoma bronchus
c)
Carcinoma cervix
d)
All of the above
29.
Cavity formation in lungs is most commonly seen in
a)
Primary Tuberculosis
b)
Secondary Tuberculosis
c)
Both of the above
d)
None of the above
30.
Following are the features of anaplasia except
a)
Hyperchromasia
b)
anisonucleosis
c)
typical mitosis
d)
prominent nucleoli
31.
Carcinomas usually spread by which route
a)
hematogenous
b)
lymphatic
c)
both of the above
d)
None of the above
32.
Epithelioid cell is a modified
a)
macrophage
b)
mast cell
c)
Eosinophil
d)
lymphocyte
33.
Presence of generalized oedema, flaky paint appearance of skin & hair changes are more commonly seen in
a)
Marasmus
b)
Radiation injury
c)
Kwashiorkor
d)
None of the above
34.
Variation in size and shape of neoplastic cell is referred to as
a)
anisonucleosis
b)
hperchromasia
c)
karryohexis
d)
karyolysis
35.
Major contribution to cachexia with advanced cancer
a)
  Clathrin
b)
Histamine
c)
Bradykinin
d)
Tumor necrosis factor-1 (TNF-1)
36.
State of hypervitaminosis occurs in -
a)
Vitamin A and B
b)
Vitamin B and C
c)
Vitamin C and D
d)
Vitamin A and D
37.
Triad of congenital syphilis includes all except
a)
Interstitial keratitis
b)
Tabes dorsalis
c)
Eighth nerve deafness
d)
Hutchinson teeth
38.
Hamartoma refers to
a)
Tumour differentiating towards more than one cell line
b)
Tumour arising from totipotent cells
c)
Mass of disorganised but mature cells indigenous to the part
d)
Mass of ectopic rests of normal tissue
39.
The following hepatotropic virus is a DNA virus:
a)
HAV
b)
HBV
c)
HCV
d)
HEV
40.
Most active form of vitamin D is
a)
7-dehydrocholesterol
b)
Ergosterol
c)
25-hydroxy vitamin D
d)
1, 25-dihydroxy vitamin D
41.
Lesion in primary syphilis is termed as
a)
Condyloma lata<br /><br />
b)
Gumma
c)
Chancre
d)
Skin rash
42.
A tumour is termed medullary when it is almost entirely composed of:
a)
Amyloid stroma
b)
Large areas of necrosis
c)
Abundant lymphoid tissue
d)
Parenchymal cells
43.
Chronic carrier state of the following hepatotropic virus infection is observed in the following except
a)
HAV
b)
HBV
c)
HCV
d)
HDV
44.
Squamous metaplasia is manifestation of which vitamin deficiency –
a)
Vitamin C
b)
Vitamin D
c)
Vitamin E
d)
Vitamin A
45.
Most common mode of transmission of syphilis is
a)
Direct contact
b)
Transfusion of infected blood
c)
Sexual contact
d)
Transplacental transmission
46.
Grading of tumours depends upon the following except
a)
Degree of anaplasia
b)
Metastatic spread
c)
Rate of growth
d)
Degree of differentiation
47.
Councilman bodies are seen in
a)
Alcoholic cirrhosis
b)
Wilson's disease
c)
Acute viral hepatitis
d)
Autoimmune hepatitis
48.
Cutaneous manifestation of Vitamin A deficiency includes
a)
Xeroderma
b)
Bitot spots
c)
Xerostomia
d)
Rose spots
49.
Women receiving oestrogen therapy have an increased risk of developing the following cancers except -
a)
Breast cancer
b)
Endometrial carcinoma
c)
Gall bladder cancer
d)
Hepatocellular carcinoma
50.
Piecemeal necrosis on liver biopsy is a feature of-
a)
Alcoholic cirrhosis
b)
Indian childhood cirrhosis
c)
Chronic hepatitis
d)
Alcoholic hepatitis
51.
Manifestations of rickets include all except
a)
Rachitic rosary
b)
Scorbutic bone
c)
Harrison's sulcus
d)
Lumbar lordosis
52.
Leukoplakia results in increased risk of –
a)
Basal cell carcinoma
b)
Squamous cell carcinoma
c)
Malignant melanoma
d)
Adenocarcinoma
53.
Ground glass hepatocytes are seen in which of the viral hepatitis
a)
HAV
b)
HBV
c)
HCV
d)
HDV
54.
Manifestations of Vitamin D deficiency include all except
a)
Osteomalacia
b)
Osteogenesis imperfecta
c)
Hypocalcemic tetany
d)
Rickets
55.
Non treponemal serological tests for syphilis include all except
a)
VDRL Test
b)
RPR Test
c)
TP passive haemagglutination test<br /><br />
d)
Reiter protein complement fixation test
56.
Regulatory genes of normal cell growth are –
a)
Proto-oncogenes
b)
Tumor suppressor genes
c)
DNA Repair genes
d)
All of the above
57.
Vitamin K dependant coagulation factors are
a)
II, VIII, IX, X
b)
V, VII, IX, X
c)
II, VII, IX, X
d)
II, VII, IX, XI
58.
UV rays are most commonly responsible for
a)
Squamous cell carcinoma
b)
Adenocarcinoma
c)
Lymphoma
d)
Leukaemia
59.
Liver biopsy in acute hepatitis shows all of the following except
a)
Ground glass hepatocytes
b)
Ballooning degeneration
c)
Dropout necrosis
d)
Councilman bodies
60.
Solar keratosis of the skin can be a risk factor for –
a)
Basal cell carcinoma
b)
Squamous cell carcinoma
c)
Adenocarcinoma
d)
Lymphoma
61.
Physiological functions of Vitamin E include all except
a)
Stimulates prostaglandin synthesis
b)
Anti-oxidant activity
c)
Scavenger of free radicals
d)
Activates protein kinase C and phospholipase A2
62.
Syphilis is caused by
a)
Treponema pertenue
b)
Treponema pallidum
c)
Treponema denticola
d)
Treponema vincentii
63.
Malignant tumor of mesenchymal origin is
a)
Adenocarcinoma
b)
Adenoma
c)
Squamous cell carcinoma
d)
Sarcoma
64.
Manifestations of vitamin C deficiency include all except
a)
Scorbutic rosary
b)
Rachitic rosary
c)
Ecchymosis
d)
Hemarthrosis
65.
How do you differentiate carcinoma in situ from invasive carcinoma
a)
Penetration of basement membrane
b)
Number of mitotic cells
c)
Metastasis
d)
Nuclear pleomorphism
66.
Causes of vitamin K deficiency include all except
a)
Anticoagulant therapy
b)
Antibiotic therapy
c)
Diffuse lung disease
d)
Diffuse liver disease
67.
Which of the following is a malignant tumor
a)
Fibroma
b)
Chondroma
c)
Lipoma
d)
Lymphoma
68.
Delayed wound healing is manifestation of which vitamin deficiency
a)
Vitamin C
b)
Vitamin K
c)
Vitamin A
d)
Vitamin E
69.
Malignant counterpart of leiomyoma is termed as
a)
Leiomyoblastoma
b)
Leiomyosarcoma
c)
Lymphoma
d)
Leukaemia
70.
Neurological manifestations are seen most commonly with which vitamin deficiency
a)
Vitamin C
b)
Vitamin K
c)
Vitamin A
d)
Vitamin E
71.
Benign tumor of adipose cells is known as
a)
fibroma
b)
osteoma
c)
lipoma
d)
chondroma
72.
Epstein-Barr viruse causes
a)
Burkitt’s lymphoma
b)
Anaplastic nasopharyngeal ca
c)
Hodgkin’s lymphoma
d)
All of the above
73.
What is metastatic adenocarcinoma of the stomach that specifically goes to the ovary called?
a)
Melanoma
b)
Krukenberg tumor
c)
Wilson's tumor
d)
Richtsler's tumor
74.
Deficiency of vitamin B1 leads to
a)
Pellagra
b)
Beri-Beri
c)
Ariboflavinosis
d)
Neural tube defect
75.
Dermoid cyst is an example of
a)
Hamartoma
b)
Choristoma
c)
Teratoma
d)
Adenoma