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WorksheetsPharmacology - III
Total questions: 30
Worksheet time: 15mins
What does “pharmacokinetics” include?
Localization of drug action
Mechanisms of drug action
Excretion of substances
Interaction of substances
Class of cyclosporine A is:
Interferons
Immunosuppressive agents
Monoclonal antibodies
Immunoglobulins
Mechanism of action of sirolimus (rapamycin) is:
Anti-idiotype antibodies against autoantibodies
Modulation of CD3 receptor from the cell surface
Inhibits calcineurin
ADCC towards T lymphocytes
Half-life of interferon gamma is:
21 Days
19 Hours
4-16 Hours
25-35 Minutes
Which of the following antibiotics contains a beta-lactam ring in their chemical structure :
Penicillins
Cephalosporins
Carbapenems and monobactams
All groups
Tick the drug belonging to antibiotics-macrolides:
Neomycin
Doxycycline
Erythromycin
Cefotaxime
Tick the drug belonging to antibiotics-tetracyclines:
Doxycycline
Streptomycin
Clarithromycin
Amoxacillin
All of antibiotics are aminoglycosides, EXCEPT:
Gentamycin
Streptomycin
Clindamycin
Neomycin
Antibiotics inhibiting the bacterial cell wall synthesis are:
Beta-lactam antibiotics
Tetracyclines
Aminoglycosides
Macrolides
Antibiotic inhibiting bacterial RNA synthesis is:
Erythromycin
Rifampin
Chloramphenicol
Imipinem
Antibiotics altering permeability of cell membranes are:
Glycopeptides
Polymyxins
Tetracyclines
Cephalosporins
All of the following antibiotics inhibit the protein synthesis in bacterial cells, EXCEPT:
Macrolides
Aminoglycosides
Glycopeptides
Tetracyclines
Which of the following drugs is a gastric acid resistant:
Penicillin G
Penicillin V
Carbenicillin
Procain penicillin
Which of the following drugs is penicillinase resistant:
Oxacillin
Amoxacillin
Bicillin-5
Penicillin G
Mechanism of penicillins’ antibacterial effect is:
Inhibition of transpeptidation in the bacterial cell wall
Inhibition of beta-lactamase in the bacterial cell
Activation of endogenous proteases, that destroy bacterial cell wall
Activation of endogenous phospholipases, which leads to alteration of cell membrane permeability
Carbapenems are effective against:
Gram-positive microorganisms
Gram-negative microorganisms
Only bacteroide infections
Broad-spectum
All of the following antibiotics are macrolides, EXCEPT:
Erythromycin
Clarithromycin
Lincomycin
Roxythromycin
Tetracyclins have following unwanted effects:
Irritation of gastrointestinal mucosa, phototoxicity
Hepatotoxicity, anti-anabolic effect
Dental hypoplasia, bone deformities
All of the above
Tick the drug belonging to antibiotics-aminoglycosides:
Erythromycin
Gentamycin
Vancomycin
Polymyxin
Aminoglycosides have the following unwanted effects:
Pancytopenia
Hepatotoxicity
Ototoxicity, nephrotoxicity
All of the above
Azoles have an antifungal effect because of:
Inhibition of cell wall synthesis
Inhibition of fungal protein synthesis
Reduction of ergosterol synthesis
Inhibition of DNA synthesis
Tick the drug belonging to antibiotics having a polyene structure:
Nystatin
Ketoconazole
Griseofulvin
All of the above
Mechanism of Streptomycin action is:
Inhibition of cell wall synthesis
Inhibition of protein synthesis
Inhibition of RNA and DNA synthesis
Inhibition of cell membranes permeability
Tick the drug, blocking acetylcholine transmission at the myoneural junction of helminthes:
Levamisole
Mebendazole
Piperazine
Niclosamide
Tick niclosamide mechanism of action:
Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes
Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes
Inhibiting oxidative phosphorylation in some species of helminthes
Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake
The drug, inhibiting viral reverse transcriptase:
Zidovudine
Vidarabine
Rimantadine
Gancyclovir
All of the following antiviral drugs are anti-influenza agents, EXCEPT:
Acyclovir
Amantadine
Interferons
Rimantadine
In COPD, where in the lungs is the primary site of obstruction?
Large bronchi
Large Bronchioles
Mucus Glands
Small Bronchi and Bronchioles
Antacid: effective, but associated with systemic alkalosis
Calcium Carbonate
Sodium Bicarbonate
Magensium Hydroxide
Aluminium Hydroxide
Tick the anticancer drug of plant origin:
Dactinomycin
Vincristine
Methotrexate
Procarbazine
