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Cervix

Total questions: 25

Worksheet time: 14mins

Name
Class
Date
1.

Which of the following is not a risk factor for HPV ?

a)

High parity

b)

Child marriage

c)

Smoking

d)

Multiple sex partners

2.

HPV can cause :

a)

Squamous cell carcinoma of cervix

b)

Adenocarcinoma cervix

c)

Small cell carcinoma cervix

d)

All of these

3.

Which of the following cells are not infected by HPV in cervix?

a)

Damaged surface cells

b)

Immature basal cells

c)

Metaplasic squamous cells

d)

Superficial undamaged cells

4.

HPV replicates in the mature proliferating squamous cells

a)

True

b)

False

5.

Proteins acted on by E7 protein include:

a)

RB

b)

p21

c)

p53

d)

p27

6.

Episomal DNA can be seen in:

a)

CIN I

b)

CIN II

c)

Condyloma acuminatum

d)

Invasive carcinoma

7.

Hormonal changes can lead to cervical cancer

a)

True

b)

False

8.

Productive HPV infection is seen in:

a)

CIN III

b)

CIN II

c)

LSIL

d)

Carcinoma

9.

Which of the following nuclear features are not seen in koilocytic atypia?

a)

Fine chromatin granules

b)

Variable size and shape

c)

Dark staining

d)

Big nucleus

10.

Koilocytes are superficial or intermediate immature squamous cells

a)

True

b)

False

11.

Diagnosis of SIL is based on:

a)

Immature atypical squamous cells

b)

Presence of koilocytes

c)

Mature cells showing metaplasia

d)

All of these

12.

Which of the following is NOT a feature of koilocytes?

a)

Perinuclear halo

b)

Prune like nuclear membrane

c)

Dense, regular staining peripheral cytoplasm

d)

Rope like chromatin

13.

Pap smear of a 30 yr old woman shows viral cytopathy on examination. The markers that could be used to confirm the virus is:

a)

Ki-57

b)

Ki-67

c)

p16

d)

p21

14.

Koilocytes are never seen in cervical invasive carcinoma

a)

True

b)

False

15.

The histology of a cervix showed that the lower 54% of cells were atypical and immature. The condition is:

a)

LSIL

b)

HSIL

c)

Condyloma acuminatum

d)

Cervicitis

16.

The biopsy from an unknown source showed cells with raisin like nucleus. The source could probably be:

a)

Clear cell renal carcinoma

b)

CIN

c)

Medulloblastoma

d)

Fibrolamellar hepatocellular carcinoma

17.

All types of invasive cervical carcinomas are usually preceded by SIL

a)

True

b)

False

18.

Cervical carcinomas usually arise in:

a)

Endocervix

b)

Ectocervix

c)

Transformation zone

d)

All of these

19.

Barrel cervix is caused by and identified by (respectively) :

a)

Infiltration, colposcopy

b)

Infiltration, palpation

c)

Exophytic growth, colposcopy

d)

Ulcerative lesion, palpation

20.

True about adenocarcinoma cervix

a)

Minimum mucin

b)

Abundant mucin

c)

Very rare

d)

Most common

21.

Non keratinising squamous cell carcinomas of cervix show no keratinisation

a)

True

b)

False

22.

The above image shows the microscopic appearance of cervix in:

a)

Keratinising squamous cell carcinoma

b)

Nonkeratinising squamous cell carcinoma

c)

Small cell carcinoma

d)

Adenocarcinoma

23.

Which of the following organs are not involved in hematogenous spread of cervical cancer?

a)

Urinary bladder

b)

Liver

c)

Lungs

d)

Bone marrow

24.

HPV vaccine is prepared from low infectious DNA free virus particles produced by recombinant technology

a)

True

b)

False

25.

Acid used in colposcopy

a)

Formic acid

b)

Acetic acid

c)

Periodic acid

d)

Hydrochloric acid