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Hepatitis quiz AMSA

Total questions: 20

Worksheet time: 20mins

Name
Class
Date
1.

All of the following are markers of active replicative chronic Hepatitis B except

a)

ALT and AST

b)

HBV DNA

c)

HBV DNA polymerase

d)

HBe Ag

2.

Which of the following is correct w.r.t. autoimmune hepatitis?

a)

It is classified as type 1 and type 2

b)

Classification is based on circulating antibodies pattern

c)

Type 1 is seen in older individuals

d)

Type 2 is seen in older adults with ANA antibodies

3.

A 35 year old man presented with a history of jaundice for last 15 days. Onset was preceded with prodromal illness. Serum was tested positive for HBsAg. Clinical diagnosis of acute hepatitis B was made. What should be the next confirmatory investigation?

a)

Anti HBeAg antibody

b)

HBe antigen

c)

Anti Hbe IgM

d)

HBV DNA by PCR

e)

None of the above

4.

A 29 year old patient is positive for HBsAg, HBeAg, and anti-HBe IgM.

but found negative for anti-HBS and anti-HBE. The probable diagnosis is

a)

Acute viral Hepatitis B

b)

Past infection with hepatitis B

c)

Anti HBe IgM administration

d)

immunization for Hep B

5.

This biopsy image of liver represents?

a)

Alcoholic hepatitis with clustered inflammatory cells

b)

Ground glass appearance by accumulation of Hep B virus in hepatocyte.

c)

Idiopathic fibrosis of liver

d)

Non-alcoholic fatty liver disease

6.

What should be given to a new born baby born to a HBs positive mother to prevent neonatal infection?

a)

Hep. B vaccine only

b)

Hep. B immunoglobulins

c)

Hep B vaccine along with immunoglobulins within 12 hrs of delivery

d)

Hep B immunoglobulins immediately with vaccine within 1 month

7.

Which of the following is a calicivirus?

a)

Hepatitis B virus

b)

Hepatitis E virus

c)

Hepatitis C virus

d)

Hepatitis A virus

8.

Which of the following viral infections show cryoglobulins in serum and can cause autoimmune hemolytic anemia?

a)

Hepatitis C

b)

Hepatitis B

c)

Hepatitis E

d)

Hepatitis A

9.

Which of the following depict HBsAg levels w.r.t. time of infection?

a)

A

b)

B

c)

C

d)

D

10.

In Hepatitis D super-infections, which of the following markers are found to be elevated

a)

Anti HDV only

b)

HBsAg, anti HBc IgG and anti HDV

c)

Anti HBc IgG and anti HDV

d)

HbSAg, anti HBcAg IgM and anti HDV

11.

Which virus infection is protective as a dual with HIV and patients tend to survive longer?

a)

HBV

b)

HGV

c)

HCV

d)

HEV

12.

Which of the following is a flavivirus?

a)

HAV

b)

HCV

c)

HEV

d)

HBV

13.

The first choice of treatment for Hepatitis B infection is ?

a)

Tenofivir

b)

Lamivudine

c)

Interferon alfa

d)

Ribavirin

14.

All of the following about hepatitis B are true, EXCEPT

a)

Vertical transmission is more common than horizontal transmission in non-endemic areas

b)

Age of onset determines prognosis

c)

Period of communicability lasts several months

d)

Virus can be detected in blood one month before jaundice appears

15.

Extrahepatic manifestations of Hepatitis C includes all, EXCEPT

a)

Lichen Planus

b)

Celiac Disease

c)

Glomerulonephritis

d)

Cryoglobulinemia

16.

TYPE 2 autoimmune hepatitis is most strongly associated with which antibodies

a)

Antinuclear antibodies (ANA)

b)

Anti SLA

c)

Anti LKM1

d)

ANCA

17.

Granulomatous hepatitis may be seen with

a)

Carbamazepine

b)

Allopurinol

c)

Phenylbutazone

d)

all of these

18.

Ratio of AST/ALT>1 is seen in

a)

Non alcoholic staetohepatitis

b)

Alcoholic hepatitis

c)

Wilson's disease

d)

All of these

19.

Which of the following is advocated as the mainstay treatment for severe alcoholic hepatitis?

a)

Glucocorticoids

b)

Thiamine

c)

Proton pump inhibitors

d)

Monoclonal Abs against TNFα

20.

Best site for giving Hepatitis B vaccine is

a)

Subcutaneous

b)

Intra-dermal

c)

Intramuscular deltoid

d)

Intramuscular gluteal