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WorksheetsCLINICAL PARASITOLOGY 2
Total questions: 88
Worksheet time: 44mins
Which parasite is the causative agent of Cutaneous Leishmaniasis?
L. tropica
L. donovani
L. braziliensis
AOT possible choices
NOTC
During microscopic inspection of a blood film, identification and diagnosis of Babesia spp. is relies on:
Parasite seen with ingested RBCs
Appearance of the parasite inside the RBCs
Size of the RBCs infected by the parasite
AOT possible choices
NOTC
Enterobius vermicularis infection is usually diagnosed by finding:
Eggs in perianal specimens
Larvae in perianal specimens
Larvae in feces
Eggs in the feces
AOTC
Cysts are the infective stage of this intestinal flagellate.
Balantidium coli
Dientamoebafragilis
Entamoeba coli
Giardia lamblia
Dormant or secondary schizogony may occur in these types of malarial species due to the presence of hypnozoites in the liver.
I. P. malariae
II. P. vivax
III. P. ovale
IV. P. falciparum
I only
II and III
I, II, and IV
I and IV
IV only
Species identification of an immature amebic cyst can be very difficult. The presence of a large glycogen mass is sometimes seen in:
Dientamoeba fragilis
Endolimax nana
Entamoeba coli
Entamoeba histolytica
Surgery is the treatment of choice for Cystic Echinococcosis.
Albendazole or Mebendazole may be used for pre/post-surgical chemotherapy of Echinoccocosis.
Only statement 1 is false
Only statement 2 is false
Both statements are true
Both statements are false
Which of the following findings in a peripheral blood smear is especially associated with tissue-invading helminthes but may also be found in a variety of allergic conditions and other diseases?
Eosinophilia
Leukopenia
Lymphocytosis
Neutropenia
NOTC
A 48-year-old man from Texas developed fever and weakness 16 days after a hunting trip in northwest Tanzania. Several days after the onset of fever, he noticed a raised, tender, erythematous nodule (6-8 cm in diameter) on the posterior aspect of his right arm. He was hospitalized in Africa and treated for 5 days with a cephalosporin for presumed cellulitis. After little improvement, he returned to Texas. On arrival, the patient had a temperature of 38.9°C (102°F), a morbilliform rash of the trunk, and rightsided, anterior cervical lymphadenopathy. Cerebrospinal fluid contained 12 red cells and 18 mononuclear cells/uL and a normal protein level (32 mg/dL). Laboratory tests of peripheral blood revealed a hemoglobin level of 107 g/L, a white cell count of 2.4 X 109/L, and a platelet count of 75 X 109/L. The diagnosis was made by finding the extracellular flagellate parasite in a peripheral blood smear. Which of the following is the most probable etiologic agent of this infection?
Leishmania donovani
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
In the case with Trypanosoma brucei, which of the following symptoms would be referred as “Winterbottom sign”?
Morbiliform rash
Erythematous nodule
Cervical Lymphadenopathy
Cerebral pleocytosis
AOTC
Which of the following would fit the characteristics of an Ophistorchis viverrini ovum?
I. Comma-shaped appendages at the abopercular end
II. Non-operculated
III. Opercular shoulders
I and II only
II and III only
I and III only
AOT possible
NOTC
A 22-year-old male presents to his family physician complaining of fatigue, muscle pain, periorbital edema, and fever. He denies travel outside the U.S. The physician suspects infectious mononucleosis; however, serologic tests for infectious mononucleosis are negative. The complete blood count revealed a slightly elevated white blood count, and there were 10% eosinophils on the differential. Which of the following should be considered part of the differential diagnosis?
Ascaris lumbricoides
Taenia solium
Trichinella spiralis
Trypanosoma cruzi
NOTC
In the case with Trichinella spiralis how is the parasite transmitted?
Ingestion infected undercooked pork
Ingestion of fecal contaminated meat
Insect bite
Transmitted from person to person
NOTC
Which of the following anti-parasitic drugs can be used as treatment for Fascioliasis?
I. Albendazole
II. Mebendazole
III. Quinidine
I only
I and II only
III only
All of the possible choices
None of the choices
A 55-year-old female presents to her physician complaining of a fever that "comes and goes" and fatigue. A complete blood count reveals decreased red blood cell count and hemoglobin. History reveals the patient recently traveled through Europe and Africa. You should suspect _.
Cutaneous larval migrans
Filariasis
Malaria
Trichinosis
NOTC
Trypanosomiasis can be diagnosed using parasite-free Reduviid Bug by letting them feed on a patient suspected of Chagas disease. This process is called _.
Serodiagnosis
Entodiagnosis
Pseudodiagnosis
Xenodiagnosis
None of the choices
Hydatid cysts in humans are due to ingestion of a tapeworm stage normally found in canines. This stage is the _.
Cercaria
Cercocystis
Cysticercus
Embryonated egg
All of the choices
With a fecal specimen, which one of the following is the most dependable procedure for the accurate, specific diagnosis of an intestinal amebic infection?
Direct saline wet mount
Direct iodine wet mount
Permanently stained smear
Formalin-ethyl acetate sedimentation technique
All of the above
The disease most commonly associated with Acanthamoeba sp. is
Diarrhea
Keratitis
Liver abscess
Meningoencephalitis
All of the following parasites are not able to cause Amebic Meningoencephalitis, except:
I. E. coli
II. E. gingivalis
III. E. hartmanii
I and II
II and III
I and III
AOTC
NOTC
Oocysts, the infective stage of Toxoplasma gondii is found in _.
Cat feces
Human feces
Undercooked pork
Undercooked beef
AOTC
Specimens that are permissible to be stained by Trichrome staining are those fixed only with _.
I. Mercuric chloride
II. 10% Formalin
III. SAF
I and II
II and III
I and III
AOTC
Which of the following helminthes produces an elongate, barrel-shaped egg (50 X 22 μm) with a colorless polar plug at each end?
Ascaris lumbricoides
Hymenolepis nana
Necator americanus
Trichuris trichiura
NOTC
Which species of Plasmodium may readily be identified when crescent-shaped gametocytes are found in stained blood films?
P. falciparum
P. malariae
P. ovale
P. vivax
AOTC
Which of the drugs can be used to treat Oxyuriasis?
I. Pyrantel pamoate
II. Praziquantel
III. Albendazole
IV. Bithionol
I only
II and IV
I and III
I, II, and III
AOTC
What free-living amoeba is the causative agent of Primary Amoebic Meningoencephalitis?
Dientamoeba fragilis
Naegleria fowleri
Entamoeba hystolytica
Entamoeba coli
NOTC
Eosinophilic stipplings of Plasmodium falciparum are termed as “James dots”.
The macrogametocytes of Plasmodium vivax have a “boat-shaped” appearance.
Only Statement 1 is True
Only Statement 2 is True
Both Statements are True
Both Statements are False
This amebic cyst has an average size of 6-8 um and is usually spherical. When mature, it has four nuclei, but immature cysts with one or two nuclei are often seen. The nuclei have fine uniform granules of peripheral chromatin and small, discrete, usually central karyosomes. Chromatoidal bars with bluntly rounded ends are sometimes present. Name the species.
Endolimax nana
Entamoeba coli
Entamoeba hartmanni
Entamoeba histolytica
NOTC
Which of the following parasites is known for causing “River Blindness”?
O. volvulus
M. ozzardi
W. bancrofti
B. malayi
What is the insect vector for O. volvulus?
Black fly
Mango fly
Deer fly
Anopheles mosquito
NOTC
Sanitary disposal of human feces is the most important factor in decreasing the incidence of most infections caused by intestinal parasites. Which of the following diseases would not be affected by that kind of sanitation?
Ascariasis
Taeniasis
Trichinosis
Hookworm infection
None of the choices
Taenia saginata cysts are called “Cysticercus bovis”.
Taenia saginata are capable of superinfection.
Only Statement 1 is true
Only Statement 1 is false
Both Statements are false
Both Statements are true
33. The rhabditiform larvae of Strongyloides stercoralis _.
Mate and produce ova
Are infective for humans
Are the diagnostic form found in feces
Are found in the blood of infected humans
AOTC
Which of the following terms are other names for Dracunculus medinensis?
I. Thread worm
II. Fiery serpent
III. Guinea worm
IV. Rat lung worm
I only
II and III
I and IV
I, II, and III
Which of the following nematode parasites is acquired from eating inadequately cooked, infected pork?
Strongyloides stercoralis
Taenia saginata
Taenia solium
Trichinella spiralis
AOTC
37. If left untreated, infection of Diphyllobothrium latum will result to what disease?
Neurocysticercosis
Taeniasis
Meningoencephalitis
Pernicious anemia
AOTC
Hematuria is a typical sign of human infection caused by:
Trypanosoma cruzi
Trichinella spiralis
Trichomonas vaginalis
Schistosoma haematobium
AOTC
T. solium has 7-15 lateral uterine branches in each proglottid.
T. saginata has 20-100 lateral uterine branches in each proglottid.
Only Statement 1 is false
Only Statement 2 is false
Both Statements are true
Both Statements are false
Which of the following is the preferred anticoagulant for preparing blood smears for diagnosing malaria?
EDTA
Heparin
Sodium citrate
Sodium fluoride
AOTC
Which of the following microfilariae are sheathed at the posterior end?
I. Onchocerca volvulus
II. Mansonella ozzardi
III. Mansonella perstans
IV. Wuchereria bancrofti
I, II, and III
I only
II & III
I & IV
NOTC
Balantidium coli is a non-pathogenic ciliate with a single nucleus.
It is one of the smallest protozoans known to man.
Only statement 1 is correct
Only statement 2 is correct
Both are correct
Neither is correct
Which of the following are terms that can be described as a P. falciparum infection?
Black water fever
Malignant tertian malaria
Subtertian malaria
All of the possible choices
None of the possible choices
Which statement is correct for specimen collection and processing?
Stool samples can contain urine.
Stools can be frozen without affecting parasitic structure.
Liquid stools are best for detecting ameba and flagellate trophozoites.
Unpreserved stools can remain at room temperature for up to 72 hours.
AOTC
Which of the following parasites can be diagnosed using a sputum sample?
I. P. westermani
II. S. stercoralis
III. T. saginata
I and II
II and III
I and III
AOTC
NOTC
E. vermicularis infection can be acquired through inhalation of parasite ova.
The gold-standard for diagnosing Enterobiasis is the cellulose tape method.
Only statement 1 is correct
Only statement 2 is correct
Both statements are false
Both statements are correct
Which of the following parasites is the causative agent of West African Sleeping Sickness?
T. cruzi
L. braziliensis
T. brucei rhodisiense
T. brucei gambiense
NOTC
Many parasites have different stages of growth within different hosts. The host where the sexual reproductive stage of the parasites exists is called the
Commensal
Definitive host
Intermediate host
Vector
NOTC
T. vaginalis can be found in the following specimens except _.
Vaginal discharge
Urine
Urethral discharge
All of the possible choices
None of the possible choices
Which of the following is important in differentiating cysts of Entamoeba histolytica from E. dispar?
Number of nuclei
Size of the cyst
Shape of the karyosome
Distinguishing surface antigens by immunologic assays
AOTC
Which of the following methods/drugs can be used as treatment for Loa loa?
I. Mebendazole
II. Surgical removal
III. Diethylcarbamazine
I and II
II and III
I and III
AOTC
NOTC
Lois is a distraught 44-year-old female visiting her primary care physician at 9:00 a.m. She describes looking in the mirror that morning and seeing a worm crawl across her eye and then disappear. On her updated patient history, she notes she had visited the African rainforest the previous year. The physician orders a stool for ova and parasite examination, as well as a complete blood count and differential. The blood is drawn at 11:30 a.m. on the same day as the office visit at a draw site near Lois’ home. The stool parasite examination proves to be negative. The automated blood count shows increased eosinophils and a Giemsa stained blood film is prepared. An evening shift medical laboratory scientist observes a worm-like form on the blood smear that is 275 μm in length. There is a stained sheath and nuclei extend to the tip of the tail.
What is the organism described in this case study?
Loa loa
Acanthamoeba spp.
Hookworm
Wuchereria bancrofti
NOTC
Lois is a distraught 44-year-old female visiting her primary care physician at 9:00 a.m. She describes looking in the mirror that morning and seeing a worm crawl across her eye and then disappear. On her updated patient history, she notes she had visited the African rainforest the previous year. The physician orders a stool for ova and parasite examination, as well as a complete blood count and differential. The blood is drawn at 11:30 a.m. on the same day as the office visit at a draw site near Lois’ home. The stool parasite examination proves to be negative. The automated blood count shows increased eosinophils and a Giemsa stained blood film is prepared. An evening shift medical laboratory scientist observes a worm-like form on the blood smear that is 275 μm in length. There is a stained sheath and nuclei extend to the tip of the tail.
What is the importance of the complete blood count ordered by the physician?
To determine where the parasite is located
To determine the degree of infection
To detect any hemorrhage that might have occured
To determine the state of the patient’s RBCs
AOTC
Which species of malaria parasite usually has ameboid trophozoites and produces small reddish dots in the red blood cell cytoplasm?
Plasmodium knowlesi
Plasmodium falciparum
Plasmodium malariae
Plasmodium vivax
None of the choices
Which of the following statements is untrue regarding Endolimax nana?
E. nana is considered as a non-human pathogen, so treatment is unnecessary.
E. nana is prevalent in areas in which poor hygiene and substandard sanitary conditions exist.
E. nana is found primarily in warm and moist regions of the world.
All of the possible choices
None of possible choices
Which of the following is a mercury containing fixative used to preserve parasites in stool specimens?
Buffered glycerol
Sodium acetate
Formalin
Polyvinyl alcohol
The condition “Swimmer’s itch” is known to be caused by which organism?
N. fowleri
Acanthamoeba spp.
S. japonicum
C. philippinensis
A systemic hypersensitivity reaction caused by the presence of Schistosoma is called which of the following?
Swamp fever
Katayama fever
Bilharziasis
Schistosomiasis
Which ova of Schistosoma species has a large terminal spine?
S. haematobium
S.japonicum
S. mansoni
S. mekongi
D. latum is unique from other cestodes because has the only non-operculated ova. D. latum ova are usually mistaken as that of Spirometra ova.
Statement 1 is false
Both statements are correct
Statement 2 is false
Both statements are false
This parasitic infection may result in vitamin B12 deficiency, and individuals with pernicious anemia are predisposed to more severe symptoms.
Diphyllobothrium latum
Echinococcus granidosus
Hymenolepis diminuta
Taenia saginata
Iron Deficiency Anemia is the result of a chronic infection of which parasite?
A. lumbricoides
H. diminuta
N. americanus
E. vermicularis
None of the choices
Which of the following helminths produces an elongate, barrel-shaped egg (50 X 22 |xm) with a colorless polar plug at each end?
Ascaris lumbricoides
Hymenolepis nana
Necator americanus
Trichuris trichiura
None of the choices
Migration of larva through the skin can sometimes produce allergic reactions called larva migrans; this is associated with
Strongyloides stercoralis
Dracunculus medinensis
Onchocerca volvulus
Loa loa
NOTC
For Taenia solium infection, ingestion of cysts from undercooked pork meat will lead to cysticercosis.
Cysticercus cellulosae can cause superinfection in a patient through fecal-oral mode of transmission.
Only statement 1 is correct
Only statement 2 is correct
Both statements are correct
Both statements are false
This parasite is commonly found on dog and cat intestines. Diagnosis of this parasite is the detection of characteristic ova( thin-shelled, no bipolar filaments, and 6 hooked oncospheres).
Hymenolepis diminuta
Hymenolepis nana
Taenia solium
Dipylidium caninum
An intestinal parasite is seen in an iodine-stained fecal wet mount that is described as being 25 (Jim in diameter with a homogenously stained central body surrounded by a thin ring of cytoplasm containing a number of nuclei. This best describes
Blastocystis hominis
Endolimax nana
Entamoeba dispar
Iodamoeba btitschlii
NOTC
Sparganosis can occur in humans with the ingestion of _ of Spirometra or Diphyllobothrium latum.
Procercoid larva
Plerocercoid larva
Metacercaria
Cercaria
NOTC
Which of the following is the largest intestinal protozoa infecting humans?
Balantidium coli
Dientamoeba fragilis
Entamoeba histolytica
Giardia lamblia
Notc
A Giemsa-stained thick blood film showed many ring forms with no older stages, and a number of the rings had double chromatin dots. These findings are characteristic of
Plasmodium falciparum
Plasmodium vivax
Plasmodium malariae
Plasmodium ovale
Notc
What is the insect vector of Mansonella perstans?
Anopheles
Culicoides
Culex
Aedes
Notc
Which of the following forms of Toxoplasma gondii are produced in infected humans?
Bradyzoites
Macrogametes
Sporoblasts
Oocysts
Notc
“Old man’s Face/Old man’s Glass” is the characteristic appearance of a trophozoite of which parasite?
I. Giardia intestinalis
II. Giardia duodenalis
III. Giardia lamblia
I and II
II and III
I and III
All of the choices
None of the choices
Chagas disease (American trypanosomiasis) is caused by
Trypanosoma brucei
Trypanosoma cruzi
Leishmania braziliensis
Dracunculus medinensis
What is the insect vector of American trypanosomiasis?
I. Triatomids
II. Kissing Bug
III. Conenose Bug
AOTC
NOTC
I & II
II & III
I & III
Trypomastigotes of T. cruzi are acquired by humans from _ of Reduviid Bugs.
Saliva
Blood
Feces
AOTC
NOTC
Eggs or larvae recovered in the stool are not routinely used to diagnose infections caused by which one of the following helminths?
Trichinella spiralis
Strongyloides stercoralis
N. americanus
Ascaris lumbricoides
NOTC
Which of the following is typical in cysts of lodamoeba butschlii?
glycogen mass
Blunt chromatoidal bars
Four nuclei with large karyosomes
Many ingested bacteria
Notc
Each of the following statements concerning Ascaris lumbricoides is correct except:
Ascaris lumbricoides is one of the largest nematodes
Ascaris lumbricoides can cause pneumonia
Both dogs and cats are intermediate host of Ascaris lumbricoides
A. lumbricoides is transmitted by ingestion of eggs
For which of the following diseases is close contact with an infected human host the most important mechanism of transmission?
Schistosomiasis
Toxoplasmosis
Trichinosis
Trichomoniasis
aotc
The miracidial hatching test helps to demonstrate the viability of:
Eggs of Taenia species
Eggs of Schistosoma species
Eggs of hookworm species
Eggs of Opisthorchis
Aotc
There are very few procedures that could be considered STAT in the diagnostic parasitology laboratory. However, several situations or request for procedures should be considered STAT, and laboratory coverage should be provided 24 hours/day. The most obvious situation would be:
Ova and parasite examination for giardiasis
Baermann concentration for Strongyloides
Cellulose tape preps for Enterobius
Blood films for malaria
The incorrect match between organism and characteristic is:
Fasciola hepatica and liver infection
Trichuris trichiura and eggs with polar plugs
Echinococcus granulosus and daughter cysts
Schistosoma mansoni and egg with terminal spine
Aotc
This condition results from the accidental ingestion of helminth eggs. In this instance the human becomes the intermediate rather than the definitive host. The correct answer is:
trichinosis
cysticercosis
ascariasis
strongyloidiasis
Notc
Charcot-Leyden crystals in stool may be associated with an immune response and are thought to be the breakdown products of:
neutrophils
eosinophils
monocytes
lymphocytes
Aotc
A useful concentration technique used to detect microfilariae is the:
Baermann's method
formalin-ethyl acetate concentration method
membrane filter method
miracidial hatching method
Aotc
Examination of a 24 hour unpreserved urine specimen is sometimes helpful in the recovery of:
Trichomonas vaginalis trophozoites
Schistosoma haematobium eggs
Enterobius vermicularis eggs
Strongyloides stercoralis larvae
Aotc
Two helminth eggs that may resemble one another are:
Diphyllobothrium latum and Paragonimus westermani
Opisthorchis sinensis and Fasciolopsis buski
Taenia saginata and Hymenolepis nana
Ascaris lumbricoides and Trichostrongylus
The zinc sulfate concentrate may not allow detection of:
Giardia lamblia cysts
Eggs of Trichuris trichiura
rhabditiform larvae of Strongyloides stercoralis
Infertile ova of Ascaris lumbricoides
Notc
