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Worksheets

Sympathetic Drugs

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

Which of the following is TRUE for Clonidine?

a)

Can not cross the Blood Brain Barrier

b)

Adverse effect includes salivation and lacrimation

c)

Slow acting for hypertension especially when given sublingually

d)

Highly lipid soluble

2.

Leo, a 6 year old child was diagnosed to have Attention Deficit Hyperactivity Disorder (ADHD). What Amphetamine variant is used to treat children with this disorder?

a)

Methamphetamine

b)

Modafinil

c)

Methylphenidate

d)

Phenmetrazine

3.

Maria, a 35 year old highschool teacher will undergo cataract surgery three days from now. What drug should not be given for this patient?

a)

Tamsulosin

b)

Alfuzosin

c)

Metyrosine

d)

TImolol

4.

Which of the following is NOT a beta antagonist?

a)

Phenoxybenzamine

b)

Acebutolol

c)

Propranolol

d)

Timolol

5.

The following alpha-adrenoceptor antagonists block alpha-1, but not alpha-2 receptors and are efficacious in benign prostatic hyperplasia and hypertension EXCEPT:

a)

Prazosin

b)

Phentolamine

c)

Doxazosin

d)

Terazosin

6.

The following are true about alpha-receptor antagonists EXCEPT:

a)

Causes lowering of peripheral vascular resistance and blood pressure

b)

Decreases resistance to urine flow

c)

May be reversible or irreversible

d)

Can elicit nasal decongestion

7.

Non selective a Blocker that binds covalently to a1>a2 receptors and primary drug for patients suffering from pheochromocytoma that can lead to Inhibition of ejaculation

a)

Phentolamine

b)

Propranolol

c)

Phenoxybenzamine

d)

Quinazoline

8.

Agonist drug that can cause adverse rebound hypertension that is why it should be reduced gradually

a)

Clonidine

b)

Methyldopa

c)

Propranolol

d)

Quinazoline

9.

Cardiovascular B1 blocker EXCEPT:

a)

Propranolol

b)

Metoprolol

c)

Nebivolol

d)

Esmolol

10.

Inhibits tyrosine hydroxylase which converts Tyr to dopa

a)

Reserpine

b)

Metyrosine

c)

Bretylium

d)

B & C

e)

NOTA

11.

The following are effects of B1 receptors, EXCEPT,

a)

Increased HR

b)

Increased renin release

c)

Increase Calcium

d)

NOTA

12.

Which of the following is/are effects of quinazoline (a1 selective blocker)

a)

Increased preload

b)

Decreased vascular resistance

c)

Decreased venous return

d)

B & C

e)

A & C

13.

Used as a pharmacologic cardiac stress test which augments myocardial contractility and promotes coronary and systemic vasodilation?

a)

Epinephrine

b)

Tizanidine

c)

Milrinone

d)

Dobutamine

14.

These glands are nonthermoregulatory, and respond to psychological stress and adrenoreceptor stimulation and contributes in sweat profusion

a)

Salivary

b)

Genitourinary

c)

Apocrine

d)

Adrenals

15.

Which of the following is a mixed-acting sympathomimetic?

a)

Phenylephrine

b)

Norepinephrine

c)

Oxymetazoline

d)

Pseudoephedrine

16.

Which of the following drugs is a selective alpha1 antagonist

a)

Prazosin

b)

Yohimbine

c)

Phentolamine

d)

Phenoxybenzamine

17.

The following are 1st generation, Classical non-selective b-blockers EXCEPT

a)

Pndolol

b)

Nadolol

c)

Atenolol

d)

TImolol

18.

Which of the following causes vasodilation using the mechanism of Nitric Oxide production

a)

Tilisolol

b)

Betaxolol

c)

Nipradolol

d)

Bevantolol

19.

Which pharmacodynamic characteristic describes a Beta-adrenergic receptor wherein the occupancy of the Beta-adrenergic receptor by drugs like Propanolol and Timolol, will not cause activation of the receptor?

a)

Pure antagonist

b)

Neutral antagonist

c)

Partial agonist

d)

Inverse agonist

20.

Which of the following is a NON-SELECTIVE, Beta-blocker?

a)

Propranolol

b)

Atenolol

c)

Esmolol

d)

Carvedilol

21.

All of the following are effects of Beta-blocker on the cardiovascular system EXCEPT:

a)

Heart failure

b)

Prolonged PR interval

c)

Bradycardia

d)

Myocardial Infarction

22.

Which of the following sympatolytics have more effect on beta 2 receptors?

a)

Metoprolol

b)

Labetalol

c)

Butoxamine

d)

Timolol

23.

Which of the following drugs are given for patients with erectile dysfunction?

a)

Tamsulosin

b)

Phentolamine

c)

Prazosin

d)

Yohibime

24.

Which of these drugs is a ultra short acting b1 selective adrenoreceptor antagonist?

a)

Esmolol

b)

Butoxamine

c)

Labetalol

d)

Carvedilol

25.

Which of the following patients should be given a beta receptor antagonist?

a)

Patient with hypothyroidism

b)

Recovering alcoholic patients

c)

A hypertensive patient with depression

d)

Patient with arrhythmia and hypoglycemic

26.

Julius, 49 year old man was given Prazosin, an alpha receptor antagonist. What will be the manifestation?

a)

Sphincters will continuously contract

b)

There will be increased activity of apocrine glands

c)

Vessels in the skin and skeletal muscles will relax

d)

Liver will stimulate gluconeogenesis

27.

TRUE or FALSE: Beta-antagonist drugs have an absolutely specific drugs for beta1 receptors, such as metroprolol, propranolol, and butoxamine

a)

TRUE

b)

FALSE

28.

Which of the following drugs raises BP and HR?

a)

Doxazosin

b)

Propranolol

c)

Carteolol

d)

Yohimbine

29.

Which of the following is selective for Alpha-2-receptor?

a)

Prazosin

b)

Propranolol

c)

Yohimbine

d)

Terasozin

30.

What could be the effect of using a non-selective beta blocker to an asthmatic patient with hypertension?

a)

Aggravates asthma attack because of bronchoconstriction

b)

Relieves asthma attack because of bronchodilation

c)

No effect

d)

NOTA