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Worksheets1005MSC Revision
Total questions: 17
Worksheet time: 17mins
Who developed the experiment to determine whether DNA replication was conservative, semiconservative or dispersive?
Frederick Griffith
Rosalind Franklin
Hershey and Chase
Meselson and Stahl
Which of the following best describes the structure of DNA?
Spiraling parallel sugar-phosphate backbones with base pairs projecting inwards
Spiraling antiparallel ribose sugar-phosphate backbones with base pairs projecting inwards
Parallel sugar-phosphate backbones with base pairs projecting outwards
Spiraling antiparallel deoxyribose sugar-phosphate backbones with base pairs projecting inwards
Which of the following enzymes part of DNA replication has exonuclease function?
Restriction Endonucleases
Helicase
DNA Polymerase
Topoisomerase
DNA replication leads to shortening of the DNA strand itself, but the complications that would normally arise is combatted by
Acetylation of chromatin
Telomeres
Methylation
Fusion of two separate DNA strands
Fill in the blanks. Xeroderma Pigmentosum is an ______ genetic defect which results in mutation of the ______ enzyme
Autosomal recessive, base excision repair
Autosomal recessive, nucleotide excision repair
Autosomal dominant, base excision repair
Autosomal dominant, nucleotide excision repair
Which of the following is true regarding transcription in prokaryotes?
Transcription occurs in the nucleus and uses a DNA template
Transcription occurs in the nucleus and uses an RNA template
Transcription occurs in the cytosol and uses a DNA template
Transcription occurs in the cytosol and uses an RNA template
Which of the following is true regarding translation in eukaryotes?
It forms single stranded DNA
It synthesizes proteins
It synthesizes an mRNA template
It synthesizes tRNA and rRNA
Which of the following mutations could not result in early termination of protein synthesis?
Silent
Nonsense
Frameshift
All mutations may result in early termination
Which of the following is the anticodon for methionine
AUC
UCA
AUG
UAC
Which of the following is true regarding gene expression?
Acetylated histone tails results in condensed chromatin and reduced gene expression
Inheritance of p53 gene contributes to an individual getting cancer
Methylation of cytosine bases results in reduced gene expression
miRNA blocks large regions of the chromosome
When tryptophan is present...
The Trp operon is transcribed because the repressor is bound to the operator
The Trp operon is transcribed because the repressor is not bound to the operator
The Trp operon is not transcribed because the repressor is bound to the operator
The Trp operon is not transcribed because the repressor is not bound to the operator
Regarding the lac operon, glucose is related to ____, and is responsible for ______
The repressor, negative control
The repressor, positive control
cAMP and CAP, negative control
cAMP and CAP, positive control
When lactose is present and glucose is high
Transcription of lac operon at low rate
Transcription of lac operon at high rate
No transcription of lac operon
No lactate production but lac operon genes are transcribed
Which of these is not an example of a segmentation gene
Gap genes
Pair-rule genes
Segment Polarity genes
Homeotic genes
Which of these is not a known teratogen?
Nicotine
Hyperthermia
Vitamin B12
Retinoic Acid
Multigene families are:
identical or similar genes that have evolved by gene duplication
usually clustered at the telomeres
equivalent to the operons of prokaryotes
sets of genes that are coordinately controlled
Why are short tandem repeats useful for forensics?
The locus of short tandem repeats differs from person to person
Number of short tandem repeats varies significantly from person to person
Only identical twins vary in the number of short tandem repeats
The number of short tandem repeats is difficult to identify by genetic research
