WorksheetsUnit 4 Revision
Total questions: 30
Worksheet time: 3600secs
Which is not the type of Artificial Neural Networks?
Feed forward
Back Propagation
Convolutional
HMM
Which of the following statement is correct for Neural Network?
Neural Network are complex Linear Functions with many parameters
Neural Network are complex Non-Linear Functions with many parameters
Neural Network are complex Discrete Functions with many parameters
Neural Network are complex Activation Functions with many parameters
An important step In a neural network is knowing the weight and bias of each neuron. A function can be approximated if you can somehow get the correct value of weight and bias for each neuron. What would be the best way to approach this?
Assign random values and pray to God they are correct
Search every possible combination of weights and biases till you get the best value
Iteratively check that after assigning a value how far you are from the best values, and slightly change the assigned values to make them better
None of these
Which of the following statement is correct for Deep learning
Deep learning refers to artificial neural networks that are composed of many layers
Deep learning refers to artificial neural networks that are composed of 5 layers
Deep learning refers to artificial neural networks that are composed of 10 layers
All of the above
Dr. John is a scientist and he examines DNA from different tissues in normal and diseased states to determine which genes and environment condition can lead to the disease. He completed the conversion of DNA to mRNA and has obtained multiple samples. The analysis has to be completed in very short duration. Which method could be used?
Decision tree
Microarray
Systems Biology
Support Vector systems
Viterbi Algorithm follows
MSA
Watermann algorithm
Needleman algorithm
Dynamic Programming
A drug has to be discovered but in a fast pace such that its development time is reduced. The scientists have decided to proceed with holistic approach to get better efficient results. Which method would be appropriate?
Support Vector machines
Synthetic Biology
Systems Biology
HMM
A customized drug has to be designed; the drug is an extracellular product obtained from recombinant bacteria. These steps are involved in?
Functional annotation
Systems Biology
Synthetic Biology
Peptide Mass fingerprinting
Consider a gene that has a sequence CCAGAGAGCCC and its biological identity has to be identified. Which method is applicable?
Sequence Tagged Sites
Functional Annotation
Structural Annotation
Peptide Mass fingerprinting
A peptide, from biochemical analysis it is found to be coronin. It is an actin binding protein which also interacts with microtubules and in some cell types is associated with phagocytosis. The peptide has to be matched with its functionality. Which approach is the most suitable?
Systems Biology
Functional Annotation
Structural Annotation
Peptide Mass fingerprinting
Very simple principles and very complex behaviors - refers to
Microarray
Systems Biology
Artificial Neural Networks
Hidden Markov Model
Artificial Neural Networks help in recognition of
Face and speech
DNA
RNA
Amino Acid
The probability of 350th state depends on
zero order state
pseudo state
previous 349 states
previous 350 states
HMM helps us to find
Organelles
RNA
Protein
Genes
Data driven method for solving classification tasks
Decision trees
HMM
Support Vector Sysem
ANN
Small changes in the training data can result in large changes to decision logic - This is a drawback of which method?
ANN
SVM
HMM
Decision trees
Synthetic Biology is
computational analysis
holistic approach
statistical approach
applying an engineering and computing mindset to Biology
Identify the important component among the following for Synthetic Biology
Hydrogen atoms
Carbon atoms
Vacuoles
Restriction enzymes
Principle behind microarrays
Blotting mechanism
Hybridization
Coupling
Apoptosis
I need to massively process data and store in large memory capacity drive with efficient energy usage. What should I choose?
SVM
DNA microarray
Decision trees
DNA computing
Which of the following is incorrect regarding GeneQuiz?
It is a web server for protein sequence annotation
Domain analysis can be done using this
Matches sequences from alignment databases
web server for protein DNA annotation
A decision tree does not include
Statements
Action stubs
Condition stubs
Rules
Assume the first condition has two values; the second condition has two values; the third condition has three values. How many rules will there be?
7
6
12
11
What happens after the DNA from the sample is applied to the DNA microarray?
the mRNA falls off the spot
the DNA comes apart
DNA is cut
the cDNA will hybridize with the single stranded DNA molecules on the microarray
In the microarray, what does the RED color indicate?
these genes are not expressed or turned off
these genes are expressed in healthy cells
these genes are expressed or turned on in cancer
there are no genes in this cell
Which sequence best describes the process for DNA microarray?
sample prep; cDNA synthesis; hybridization;scan and analysis
hybridization; cDNA synthesis; scan and analysis
cDNA synthesis; scan and analysis; sample prep; hybridization
sample prep; cDNA synthesis; scan and analysis; hybridization
The first step in rational drug design is to
identify the target molecule
test the drug molecule
characterize the shape of the target molecule
find a lead
Which of these statements best describes a lead compound?
A compound that contains the element lead
A molecule that shows some activity or property of interest and serves as the starting point for the development of a drug
A compound from the research laboratory that is chosen to go forward for preclinical and clinical trials
The first compound of a structural class of compounds to reach the market.
Which of the following is NOT a part of the Investigational New Drug (IND) Review?
Review of preclinical trial results
Identification of side effect profile
Authorization to ship across the state lines
Determination of safety in human use
From the below list, choose the tool that is used for the validation of homology model of the lead compound
BLAST
Verify3D
MSA
NCBI
