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WorksheetsKULIAH SB015 CHAPTER 7 (7.1-7.2)
Total questions: 16
Worksheet time: 9mins
What type of gene mutation shown in FIGURE 1.
Normal DNA
AAC TGA GGC CTT CTT
Leu Thr Pro Glu Glu
Abnormal DNA
AAC TGA GGC CAT CTT
Leu Thr Pro Val Glu
FIGURE 1
Base Substitution
Base Deletion
Base Insertion
Base inversion
What type of gene mutation occurred when a pair of nucleotide is REPLACED with another pair of nucleotide in the DNA sequence.
Base deletion
Base substitution
Base insertion
Base inversion
Which one is NOT effect of base substitution?
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Which of the following statements is NOT TRUE about missense mutation.
mRNA codon is changed
Encoded for different amino acid
Will caused disorder which is sickle cell anemia
Produce non functional protein
Which of the following statements is TRUE about the effect of base substitution
Missense mutation - usually produce nonfunctional protein
Nonsense mutation - codes for a different amino acids
Frameshift mutation - changes entirely sequence of amino acids
Silent mutation - codes for the same amino acids
What type of mutation is the result of an insertion?
Silent Mutation
Missense mutation
Frameshift mutation
Nonsense mutation
Which type of mutation is normally more severe because they affect more than one codon?
Point Mutations
Substitution mutations
mutations where A's are replaced with T's
Frameshift Mutaitons
What type of mutation occurs, when an extra base has been added to the sequence of bases?
Base insertion
Base deletion
Base inversion
Base substitution
ATTTGAGCC- Original
ATTGAGCC - Mutated
The example above is an example of a
Base insertion
Base deletion
Base inversion
Base substitution
Which of the following is TRUE about base inversion? (answer can be more than ONE)
Two or more nucleotides are inverted
Small region of DNA breaks off and rotates 180o before rejoin
One type of gene mutation
Changes of amino acid sequence
Mutation is a spontaneous change that occur in ...... (answer can be more than ONE)
Amount of DNA
Arrangement of genes
Structure of DNA
Structure of protein
1. Which ONE is NOT a type of gene mutation?
Base substitution
Base duplication
Base deletion
Base inversion
1. Which of the following are types of chromosomal aberration ? (answer can be more than ONE)
Insertion
Inversion
Deletion
Substitution
1. Induced mutation occur due to
DNA damage caused by mutagen
Natural changes in DNA structure
Errors during DNA replication
Non-disjunction of chromosome
1. Spontaneous mutation occur due to ... (answer can be more than ONE)
DNA damage caused by mutagen
Natural changes due to chemical factor
Errors during DNA replication
Non-disjunction of chromosome
1. Which of the following is NOT physical mutagen?
UV rays
Gamma rays
Colchicine
X-ray
