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Worksheetschapter 7 mutation
Total questions: 35
Worksheet time: 23mins
Which type of mutation occurs when there is an addition or removal of a base?
missense mutation
nonsense mutation
frameshift mutation
point mutation
What type of mutation is shown in the diagram?
Point mutation - missense
Frameshift Mutation - deletion
Frameshift Mutation - addition
Point mutation - nonsense
A type of mutation that affect every codon beyond the point of mutation.
Point Mutation
Silent Mutation
Nonsense Mutation
Frameshift Mutation
What type of mutation is this?
Nonsense mutation
Missense mutation
Silent mutation
Frameshift mutation
Occurs when the DNA change does not alter the amino acid sequence of the polypeptide.
Frameshift Mutation
Insertion
Missense mutation
Silent Mutation
The change in the second codon of DNA sequence from GAA to GAG does not affect the amino acid sequence. This is an example of ........................................
Nonsense mutation
Missense mutation
Silent Mutation
Frameshift Mutation
Which of the following statement is NOT true?
Point mutation involves a chemical change in just one base pair.
Frameshift mutation occurs when there is an addition or removal of a base.
Nonsense mutation occurs when the DNA change creates a stop codon that causes the translation to terminate early.
Point mutation affect every codon beyond the point of mutation .
Chromosomal mutation is a change in ____________ (answer can be more than ONE)
Amount of DNA
Arrangement of gene
Number of chromosome
Structure of chromosome
Which ONE is NOT a type of chromosomal aberration?
Deletion
Insertion
Inversion
Translocation
Which of the following are types of Euploidy? (answer can be more than ONE)
Polyploidy
Aneuploidy
Allopolyploidy
Autopolyploidy
A chromosome is found to be shorter than it's homologous match. Which type of mutation involved?
insertion
deletion
translocation
inversion
Chromosomal number alterations refer to __________.
Changes in structure of chromosome
Changes in sequence of bases in DNA
Changes in numbers of chromosomes
Changes in numbers of organisms
Addition or deletion of single number of chromosome refers to ____________
Aneuploidy
Euploidy
Autopolyploidy
Allopolyploidy
chromosomal alteration occur due to ______________.
crossing over
nondisjunction
anaphase I
prophase II
The following karyotype illustrates an example of which syndrome?
Turner Syndrome
Klienfelter Syndrome
Edward Syndrome
Down Syndrome
Which Karyotype displays a female with Down syndrome?
ATG CCA AAT
ATG CCA AAT
Which one is NOT effect of base substitution?
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
What type of mutation occurs, when an extra base has been added to the sequence of bases?
Base insertion
Base deletion
Base inversion
Base substitution
Which of the following is TRUE about base inversion? (answer can be more than ONE)
Two or more nucleotides are inverted
Small region of DNA breaks off and rotates 180o before rejoin
One type of gene mutation
Changes of amino acid sequence
1. Induced mutation occur due to
DNA damage caused by mutagen
Natural changes in DNA structure
Errors during DNA replication
Non-disjunction of chromosome
1. Spontaneous mutation occur due to ... (answer can be more than ONE)
DNA damage caused by mutagen
Natural changes due to chemical factor
Errors during DNA replication
Non-disjunction of chromosome
1. Which of the following is NOT physical mutagen?
UV rays
Gamma rays
Colchicine
X-ray
Trisomy 21suggests that an individual has
Three copies of chromosome 21
Twenty one copies of chromosome 3
Three pairs of chromosome 21
Two copies of chromosome 21
Why is nondisjunction in Meiosis I is more deleterious than nondisjunction in in Meiosis II?
All gametes formed are abnormal
75% of the gametes formed are abnormal
50% of the gametes formed are abnormal
25% of the gametes formed are normal
Nondisjunction of sex chromosomes may occur during meiosis I of spermatogenesis. Which of the following are the possible genotypes of the zygote if the normal ovum is fertilised by these two types of the sperms?
XXY and YO
XYY and YO
XXY and XO
XYY and XO
Which of the following is caused by deletion by a large part of short arm of chromosome 5?
Cri-Du-Chat
Thalassemia
Down syndrome
Sickle cell anaemia
Polyploidy refers to
Multiple ribosomes present on a single mRNA
a chromosome which has replicated but not divided
an individual with extra sets of chromosomes
extra copies of gene adjacent to each other on a chromosome
All these are TRUE about Turner syndrome, EXCEPT..
A disorder that affects female
The syndrome is known as Monosomy X
Affected individual has webbed neck
A disorder with an extra X chromosome
Which of the following statement about non-disjunction is FALSE?
May produce a polyploidy
Give rise to Turner and Klinefelter syndrome
Only happens during Anaphase I of meiosis
Give rise to abnormalities in the number of both sex chromosomes and autosomes.
