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Pharmacology-prefinals exam

Total questions: 50

Worksheet time: 17mins

Name
Class
Date
1.

The following are anti-influenza virus drug, except:

a)

Peramivir

b)

Adefovir

c)

Amantadine

d)

Rimantadine

2.

The nurse provides instructions to a client receiving an antineoplastic medication. When implementing the plan, the nurse tells the client to?

a)

To eat high fiber rich food.

b)

To drink beverages containing alcohol in moderate amount during the evening.

c)

To take acetysalicylic acid as needed for headache.

d)

To consult with the healthcare providers before recieving immunization.

3.

Which of the following statements best explain the mechanism of action of antifungal action of amphotericin B?

a)

Inhibition of topoisomerase II

b)

Impairement of the normal permeability of fungal cell membrane.

c)

inhibition of reverse transcriptase.

d)

Blockage of fungal mitosis

4.

Which of the following antifungal drug that inhibits synthesis of ergosterol?

a)

Ketoconazole

b)

Flouracil

c)

Flucytosine

d)

Cytarabine

5.

Which of the following is an example of an Azole?

a)

Flucytosine

b)

Nystatin

c)

Griseofulvin

d)

Miconazole

6.

The patient with non-hodgkin's lymphoma is being managed with Vincristine(vinsicar). Which of the following indicates a side effects specific to this medication?

a)

Neutropenia

b)

Chest heaviness

c)

Weight gain

d)

Peripheral neuritis

7.

Which of the following is the drug of choice for amebiasis?

a)

Pyrimethamine

b)

Nitazoxanide

c)

Meteonidazole

d)

Quinidine

8.

The following are the adverse effect of Chloroquine, EXCEPT:

a)

Headache

b)

Metallic taste

c)

Skin rash

d)

blurred of vision

9.

True or False:


Vermicide are drugs that expel infesting helminths.

(a)  

10.

Which of the following is a high active drug against Ascaris and Enterobius?

a)

Piperazine

b)

Pyrantel Pamoate

c)

Diethyl Carbamazine Citrate

d)

Thiabendazole

11.

This is the first drug for Filariasis caused by Nematodes, Wuchereria bancrofti and Brugia malayi.

a)

Albendazole sulfide

b)

Mebendazole

c)

Tiabendazole

d)

Diethyl Carbamazine Citrate

12.

Which of the following are antineoplastic agents that affects protein synthesis?

a)

Doxorubicin

b)

L-asparanigase

c)

Cisplatin and carboplantin

d)

Camptothecins

13.

The following are antineoplastic medicines that destroys the DNA structure,EXCEPT:

a)

Camptothecins

b)

Ciplastin

c)

Carboplastin

d)

Hydroxyurea

14.

This antineoplastic drug enhances polymerarion and promotes microtubule assembly.

a)

Docetaxel

b)

Vinblastin

c)

Paclitaxal

d)

Etoposide

15.

This hormone is used in temporary remission in some cases of advance and metastatic endometrial carcinoma.

a)

Estrogen

b)

GnRH agonist

c)

Progestin

d)

Clucocorticoids

16.

True or False:


One of the benefits of giving antineoplastic drugs to a cancer patient is "palliative".

(a)  

17.

This antineoplastic drug is indicated to patients with Oat cell carcinoma of the lung.

a)

Procarbazine

b)

L-asparaginase

c)

Hyroxyurea

d)

Mitomycin

18.

Which of the following is an anti-herpes drug?

a)

Entecavir

b)

Oseltamivir

c)

Peramivir

d)

Acyclovir

19.

This antiviral drug is used to treat infection with Cytomegalovirus(CMV).

a)

Acyclovir

b)

Ribavirin

c)

Amantadine

d)

Ganciclovir

20.

The following are protease inhibitor that prevents viral replication, EXCEPT:

a)

Amprenavir

b)

Nelfinavir

c)

Enfuvirtide

d)

Ritonavir

21.

This hormone is primarily used in childhood acute leukemia and lymphomas and secondary effect in breast cancer.

a)

Progestin

b)

Glucocorticoids

c)

Estrogens

d)

anti Androgen

22.

Which of the following is NOT true about antiretroviral drugs?

a)

Some drugs stimulate the body's imune system

b)

It interefer with viral nucleic acid synthesis

c)

Best responses to antiretroviral drugs are in patients with incompetent immune systems

d)

Able to enter cells infected with virus

23.

This narrow antiretroviral spectrum is active only against influenza A virus.

a)

Symmetrel

b)

Flumadine

c)

Zovirax

d)

Cytovene

24.

Fungi have rigid cell wall that composed of _______.

a)

ergosterol

b)

cholesterol

c)

chitin

d)

Protein

25.

Pyrantel Pamoate has high efficacy rate towards the following helminths, except:

a)

Ascaris

b)

Filariasis

c)

Ancylostoma

d)

Enterobius

26.

Which of the following is the resulting toxic dose of Piperazine?

a)

nausea

b)

urticaria

c)

convulsions

d)

abdominal discomfort

27.

Thi antineoplastic agent is given to patient with childhood acute lymphoblastic leukemia and chorioepithelioma.

a)

nitrosourea

b)

methotrixate

c)

cycloohosphamide

d)

mechlorethamine

28.

Which of the following Pyrimidine Antagonists converts to 5F- dUMP and inhibit thynidylate synthase and block the synthesis of dtMP?

a)

Cytarabine

b)

Fluorouracil

c)

Azathioprine

d)

Busulfan

29.

True or False:

One of the side effects of antineoplastic drugs is it has a toxic effects on normal cells.

(a)  

30.

Which of the following Camptothecin Analogues is used for colorectal carcinoma and cancer of the lungs,cervix and ovary?

a)

Topotecan

b)

Etoposide

c)

Dactinomycin

d)

Irinotecan

31.

What happens during the "delayed phase" in an inflammatory response?

a)

Tissue degeneration and fibrosis occurs

b)

increasing permeability of the blood vessels.

c)

Infiltration of leukocytes and phagocytic cells to the injured or inflammed tissue

d)

Local vasodilation and increased blood flow causes the rednesss and increased heat.

32.

A sign of an inflammation that is due to local release of enzymes and increased tissue pressure.

a)

Pain

b)

Redness

c)

Swelling

d)

Heat

33.

The following are Acetic Derivatives drugs, Except:

a)

Ketoprofen

b)

Indomethacin

c)

Sulindac

d)

Etodolac

34.

What is the generic name of Celcox.

(a)  

35.

Which of the following is an antidote for Acetaminophen toxicity?

a)

Panadol

b)

Celebra

c)

N-acetylcysteine

d)

Nabuco

36.

This is used to treat Rheumatoid Arthritis, ankylosing spondylitis and osteoarthritis.

a)

Meloxicam

b)

Reliefex

c)

Otamol

d)

Acamol

37.

Which of the following is an Heteroaryl Acetic Acids drug?

a)

Indocin

b)

Mobicol

c)

Advil

d)

Ketorolac

38.

The nurse assess the patient for transient renal insuffuciency and jaundice as one of the adverse effects in taking Acetic Acid Derivatives drugs such as Sulindac. She also takes note on the elevation of the test values of which laboratory tests?

a)

Lipid Panel

b)

Liver Panel

c)

Creatinine

d)

WBC

39.

Drug of choice for Malaria

a)

Nitazoxanide

b)

Tinidazole

c)

Suramin

d)

Chloroquine

40.

What instruction you can give to a patient taking Albendazole to enhanced its effectivity?

a)

Take before meals

b)

To be taken after meals

c)

Low salt and low fat diet

d)

High fat meal

41.

This type of fungal infection affects the muscle and connective tissue immediately below the skin.

a)

Superficial mycoses

b)

Subcutaneous mycoses

c)

Systemic mycoses

d)

Allergic mycoses

42.

During an assesent to a client, The oncology nurse remembers the pneumonics "CAUTION" for warning signs of neoplasm. In which,the letter "U" means?

(a)  

43.

This drug should be avoided in children and teenagers with viral infections such as varicella or influenza.

a)

Acetic acid derivatives

b)

Proprionic acid derivatives

c)

Salicylate

d)

Acetaminophen

44.

The analgesic and antipyretic of choice for children with viral infections or chicken pox.

a)

Diclofenac

b)

Nabuco

c)

Celecoxib

d)

Acetaminophen

45.

Which of the following is NOT a therapeutic action of Aspirin?

a)

Antipyretic

b)

Antihypertensive

c)

Analgesic

d)

Anti-inflammatory

46.

The following statements best describes the role of prostaglandins as local mediators, except:

a)

Act as locally tissues in which thery are synthesized

b)

Are rapidly metabolized to inactive products at their sites of action.

c)

Glycerolipids and triglycerides are related lipids thay are synthesized from the same precursors as the prostaglandins

d)

Prostaglandins and related compounds are produced in minute quantities by vurtually all tissues

47.

viral replication.

1. Assembly of virions.

2. Attachment to the host.

3. Production of viral subunits.

4. Release of virions.

5. Control of DNA,RNA and/or protein production.

6. Uncoating of virus, and entry of viral nucleic acid into host cell nucleus.


Which if the following is the correct seuence of viral replication?

a)

1-3-5-6-2-4

b)

2-6-3-1-4-5

c)

2-6-5-3-1-4

d)

3-6-2-5-4-1

48.

Which of the following is NOT true about NSAIDS?

a)

NSAIDs are not recommended during pregnancy.

b)

NSAIDs increase renal blood flow.

c)

NSAIDs reduce the effect of SSRIs

d)

NSAIDs have a hypocoagulability effect.

49.

True or False:

Paracetamol is an NSAID with a comparatively low anti-inflammatory effect compared to other NSAIDs.

(a)  

50.

Which point in the replication cycle appears most easily blocked by antiviral drugs?

a)

Virus absorption

b)

Virus penetration

c)

Virus RNA and DNA replication

d)

Exit of virus from the cell.

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