Worksheetscc
Total questions: 50
Worksheet time: 27mins
Formula for serum osmolality:
(2Na+) + (Glucose/20) + (BUN/3)
(Na+/3) + (2Glucose) + (BUN/20)
Na+ + 3Glucose + 2BUN
Na+ - ( Cl- + total CO2)
Later models of flame photometer uses_____ as an internal standard that allows the operator to measure sodium, potassium and lithium directly.
Lithium
Cesium
Magnesium
Calcium
When measuring potassium using an ion selective electrode, the membrane is composed of:
Glass
Plastic
Silver
Valinomycin
Which electrolytes are elevated in cystic fibrosis?
Calcium and chloride
Chloride and sodium
Sodium and potassium
Potassium and chloride
In the blood, bicarbonate leaves the red blood cell and enters the plasma through an exchange mechanism with:
Sodium
Potassium
Chloride
Phosphate
It is an essential component of the glucose tolerance factor, thought to play a role in maintaining normal insulin response to glucose load by affecting membrane response to insulin:
Chromium
Zinc
Nickel
Molybdenum
Increased chloride levels as determined by colorimetric and ion-selective electrode methods may be caused by the presence in the solution of:
Bromide
Calcium
Hydrogen
Chylomicrons
Which of the following is the primary mechanism causing respiratory alkalosis?
Hyperventilation
Hypoventilation
Deficient pulmonary perfusion
Parasympathetic inhibition
If a blood gas specimen is left exposed to the air for an extended period of time, which of the following changes will occur?
PO2 and pH increase; PCO2 decreases
PO2 and pH decrease; PCO2 increases
PO2 increases; pH and PCO2 decrease
PO2 decreases; pH and PCO2 increase
Sealed heparinized arterial blood was left at room temperature for 2 hours. The most likely changes in PO2 (mmHg), PCO2(mm Hg), and pH, respectively, are:
Increase, increase and increase
Decrease, decrease, and decrease
Decrease, increase, and decrease
Decrease, decrease, and increase
The adrenal medulla secretes which of the following in the greatest quantity?
Metanephrine
Noradrenaline
Epinephrine
Dopamine
Homovanillic acid is the principal urine metabolite of:
Norepinephrine
Epinephrine
Adrenaline
Dopamine
Diurnal variation is important to consider when collecting blood for the assay of:
Catecholamines
Creatinine
Cortisol
Thyroid hormones
T3 uptake is actually a measurement of:
T3
T4
TBG
Free thyroxine
Active hormonal form of T3 an T4:
Those bound to TBG
Those bound to albumin
Those bound to transthyretin
Those in free form
The principle is based on the reaction of urinary estrogen with a mixture of phenol and sulfuric acid to produce pink color. This refers to:
Kober reaction
Trinder reaction
Zimmermann reaction
Porter-Silber reaction
The Kober reaction is used in the assay of:
Urinary estrogen
Glucocorticoids
Testosterone
Epinephrine
In the Porter-Silber assay, the dihydroxyacetone side chain of the steroid hormone reacts with:
Sulfuric acid-hydroquinone and forms reddish-brown color
m-dinitrobenzene and forms purple color
Ceric and arsenite compound and forms a yellow product
2, 4–dinitrophenylhydrazine and forms a yellow derivative
The assay employed for 17-ketosteroids, in which steroids react with m-dinitrobenzene in alcoholic KOH solution resulting to the formation of a purple color:
Kober Reaction
Zimmerman reaction
Porter-Silber Reaction
Pisano Method
Zollinger-Ellison syndrome is characterized by elevated blood levels of:
Cholecystokinin
Trypsin
Pepsin
Gastrin
Tumor marker most useful in the detection of familial medullary carcinoma of the thyroid:
Calcitonin
CA 125
CEA
CA 19-9
What metal toxin in urine is detected by the Reinsch test?
Lead
Mercury
Bromide
Zinc
Trinder’s reagent (mercuric chloride, HCl, and ferric nitrate) is used in the colometric assay for:
Acetaminophen
Salicylate
Theophylline
Ethanol
Caffeine is an important metabolite of this drug, which is assayed in newborns and young children to monitor its therapeutic level. What is this?
Acetaminophen
Digoxin
Theophylline
Phenobarbital
Odor of bitter almond gives a clue of:
Cyanide poisoning
Ethanol poisoning
Arsenic poisoning
Carbon monoxide poisoning
Benzoylecgonine is the major metabolite of:
Heroin
Marijuana
Cocaine
Phencyclidine
The formation of this crystal in urine, although not a constant finding is an important diagnostic clue of ethylene glycol poisoning:
Uric acid
Ammonium biurate
Triple phosphate
Calcium oxalate
What is the major carrier of drugs in the circulation?
Albumin
Globulin
Transferrin
Hemoglobin
Fire extinguishers designated as Class A are used for:
Paper and wood
Electrical equipment fire
Flammable liquids and gases
AOTA
It is a specialized colorimeter designed to scan and quantitate electrophoresis patterns:
Densitometer
Detector
Atomizer
Monochromator
The element that distinguishes proteins from carbohydrate and lipid compounds is:
Carbon
Oxygen
Nitrogen
Phosphorus
Parfentjev’s method is for the determination of:
Fibrinogen
Albumin
Globulin
Amylase
Apolipoprotein A is the primary protein component of:
HDL
IDL
LDL
VLDL
It is biologically important, as it serves as the starting point in many metabolic pathways including Vitamin D synthesis, steroid hormone synthesis, and bile acid metabolism.
Cholesterol
Phospholipid
Triglycerides
Free fatty acids
What is the current reference method for cholesterol analysis?
Abell-Kendall method
Bloor’s method
Salkowski method
Lieberman-Burchardt
A mild condition that appears to result from a genetic defect in transport of bilirubin from sinusoidal blood into the hepatocyte:
Gilbert Syndrome
Crigler-Najjar Syndrome
Dubin-Johnson
Rotor Syndrome
What reagent is used in the Evelyn-Malloy method to dissociate the unconjugated bilirubin from protein?
Methanol
Ethanol
Caffeine
Acetic acid
The Jaffe reaction is employed for the quantitation of:
Urea
Creatinine
Protein
Uric acid
Lloyd’s reagent improves the specificity of what colorimetric method of determination?
Jaffe
Caraway
Lieberman-Burchardt
Biuret
What is the major end product of protein and amino acid catabolism?
Urea
Uric acid
Creatinine
Creatine
Uric acid when oxidized by the enzyme uricase is transformed to:
Allantoin
Monosodium urate
Xanthine
Ammonia
The sweat chloride test is useful in the diagnosis of:
Dehydration
Cystic fibrosis
Azotemia
Diabetes
Which trace metal accumulates in Wilson’s disease?
Cobalt
Copper
Nickel
Zinc
The pH of blood is critically maintained at what level:
7.00-7.50
7.50-7.70
7.15-7.35
7.35-7.45
In which of the following are the thyroid hormones classified:
Amino acid derivatives
Steroid hormones
Fatty acid derivatives
Peptide hormones
Which of the following polypeptide hormones may be described as having alpha chains that are biochemically identical but beta chains that are biochemically unique?
FSH, TSH, ACTH, LH
TSH, LH, TRH, HCG
LH, ACTH, HCG, TRH
HCG, FSH, TSH, LH
The thyroid gland produces all of the following hormones EXCEPT:
TSH
Calcitonin
Thyroxine
Triidothyronine
In hypothyroidism, one would expect the total T4 level to be _____, and the T3 uptake to be ____.
Increased, increased
Decreased, decreased
Decreased, increased
Increased, decreased
How can primary hypothyroidism be differentiated from secondary hypothyroidism?
T3
T4
TSH
T3 and T4
5-Hydroxyindoleacetic acid is the primary metabolite of:
Epinephrine
Prolactin
Norepinephrine
Serotonin
