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Year 2 Endocrine

Total questions: 21

Worksheet time: 13mins

Name
Class
Date
1.

Classical triad of clinical features of diabetes mellitus

a)

Polyuria

b)

Unexplained weight loss

c)

Polydipsia

d)

Polyphagia

2.

Most commin ANTERIOR PITUITARY disorders

a)

Hyperplasia

b)

Tumors

c)

Hemorrhage

d)

Necrosis

3.

Pituitary adenomas usually composed of single cell type

a)

True

b)

False

4.

Nephrogenic diabetes insipidus is due to

a)

ADH dificiency

b)

Renal tubule unresponsiveness toward circulating ADH

5.

Clinical manifestations of syndrome of inappropriate ADH (SIADH) secretion

a)

Hyponatremia

b)

Polyuria

c)

Cerebral edema

d)

Resultant neurologic dysfunction

6.

GnRH receptor agonists are

a)

Lutropin

b)

Leuprolide

c)

Follitropin

d)

Goserelin

7.

What drug need to be given for oatient with mutation in gene that encodes GH receptor?

a)

Atosiban

b)

Somatropin

c)

Bromocriptine

d)

Mecasermin

8.

Indirect effects of viral infections are

a)

Damage of virus infected endocrine cells (viral replication, proliferation & assembly)

b)

Alteration of hormonal activity by viral gene products

c)

Damage of virus infected endocrine organs (immune reaction)

d)

Damage against uninfected endocrine organs (autoimmune mechanism)

9.

mumps infection can cause orchitis to male patient

a)

True

b)

False

10.

Wich of these are categorized as Hyperadrenalism?

a)

Cushing syndrome

b)

Adrenogenital syndromes

c)

Hypoaldosteronism

d)

Hyperaldosteronism

11.

Secondary hyperaldosteronism is caused by

a)

Adrenocortical neoplasms

b)

Familial hyperaldosteronism

c)

Cushing syndrome

d)

Primary hyperaldosteronism

12.

2 androgens that are produced by adrenal cortex

a)

Renin

b)

Dihydroepiandrosterone (DHEA)

c)

Androstenedione

d)

Aldosterone

13.

Parathyroid hormone is regulate by trophic hormones secreted by hypothalamus and pituitary

a)

True

b)

False

14.

Causes of primary hyperparathyroidism

a)

Parathyroid adenoma

b)

Parathyroid hyperplasia

c)

Parathyroid carcinoma

d)

Renal failure

15.

Parenteral drug therapy of DM is mainly for

a)

Type 1 DM

b)

Type 2 DM

c)

Gestational DM

d)

Diabetes insipidus

16.

Type 1 Diabetes Mellitus is due to tissue resistance toward insulin

a)

True

b)

False

17.

Which of these are examples of incretin mimetics?

a)

Glumepiride

b)

Metformin

c)

Exenatide

d)

Liraglutide

18.

Role of corticosteroids

a)

Immunosuppressive action

b)

Antibacterial action

c)

Anti inflammatory action

d)

Increase serum insulin level

19.

Start with lowest dose of corticosteroids in mild cases

a)

True

b)

False

20.

Dexamethasone suppression test is used for test

a)

Cushing disease

b)

Addison disease

c)

Hyperthyroidism

21.

Which of these are true statements for adrenocortical neoplasms

a)

Adenomas mostly secrete cortisol and aldosterone

b)

Carcinomas mostly secrete adrenal androgens

c)

Adenomas mostly not produce any clinical symptoms & are non functional