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WorksheetsPharm II Midterm
Total questions: 100
Worksheet time: 51mins
Insulin promotes fuel storage (glucose OUT of blood), and Glucagon promotes fuel mobilization (glucose INTO blood)
True
False
Diabetes Mellitus- Type 1 (non-insulin dependant), Type 2 (insulin dependant)
True
False
Obesity is a risk factor for this type of diabetes and usually occurs in persons older than 40.
Type 1
Type 2
Oral surgery in a client with Diabetes Mellitus should be performed ___________ hours after the patient has eaten a normal breakfast and has taken regular anti-diabetes medication.
2-3
1.5-2
3-4
4-6
The oral complaints of pain and discomfort related to the tongue and other oral structures are related to diabetic
neuropathy
macroangiopathy
Contributing factors to gangrene in the extremities of diabetic patients include
Poor Eyesight
Poor circulation
Reduced sensation in the extremeties
Increased sensation in the extremities
The most common adverse effect of using insulin to treat type 1 diabetes is
Hypoglycaemia
Hyperglycaemia
Hypertension
Hypotension
Which of the following can interact with SULFONYLUREAS to produce a decrease in serum glucose level (which is not clinically significant unless the diabetic patient is especially brittle)
NSAIDS
Opioids
Coumadin
Aspirin
The first line of treatment for Type II diabetes is usually a __________ and or a biguanide.
Insulin
Sulfonylurea
Pramlintide
Bile Acid Sequestrates
Metformin (Glucophage) is the most common biguanide. An adverse reaction of metformin occurs primarily in the GI tract.
True
False
Treatment of hypoglycaemia includes intravenous dextrose if client is conscious.
True
False
Patients with diabetes are at an increased risk for caries.
True
False
According to the CDHO, Invasive dental care should not be provided when blood glucose levels are
< 3.9 or >11.1
< 2.9 or > 12.1
< 3.9 or < 6.1
Which of the following blood glucose readings will lead to dismissal of a client?
11.1 or less
11.2 to 13.3
13.4 or higher
Also known as the MASTER gland
Pituitary Gland
Adrenal Gland
Anterior pituitary secretes
LH and FSH
Vasopressin and Oxytocin
hCH is used in infertility to stimulate ovarian follicle development.
True
False
_________ stimulates pituitary function and is also used to treat infertility.
Leuprolide
Menotropin
Pergonal
Synthetic oxytocin used via injection or intra orally to
Induce Labour
Control postpartum hemorrhage
Induce postpartum lactation
Inhibit Labour
Simple loiter is quite prevalent in some areas of the world because iodine is abundant in most foods.
True
False
Dental disorders exhibited by Cretins (hypothyroidism in small child) include
Malocclusion
Delayed tooth eruption
Increased tendency to develop perio
Poorly shaped teeth/carious
Inflamed, pale, or enlarged gingiva
Pregnant women with hypothyroidism tend to give birth to offspring with SMALL teeth.
True
False
Common medications used to treat hypothyroidism include
Levothyroxine (Synthroid)
Liothyronine
Liotrix
All of the above
Diffuse toxic goiter
Graves disease
Plummer disease
Exophthalmos is a characteristic sign of
Hypothyroidism
Hyperthyroidism
Hypoglycemia
Hyperglycaemia
Epinephrine is relatively safe to administer to patients with hyperthyroidism.
True
False
Patients with hypothyroidism require higher than usual doses of sedatives, analgesics, and LA.
True
False
Drug of choice for patients over 21 with hyperthyroidism is Radioactive Iodine (1321).
true
false
The most common side effects of estrogen therapy are
nausea, vomitting
nausea, diarrhea
diarrhea, sweating
tachycardia, vomitting
____________ in estrogen and progestin levels are associated with gingivitis.
Increases
Decreases
Dry socket is a common side effect in clients taking hormonal contraceptives. The risk can be minimized by timing the extraction to match the hormonal cycle.
True True
True False
False True
False False
Antibiotics may enhance the effectiveness of oral contraceptives.
True
False
Used for palliative treatment of advanced breast cancer in postmenopausal women.
Tamoxifen
Benzodiazepines
Amoxifen
Tetracycline
Used in dentistry topically or systemically for treatment of oral lesions associated with inflammatory disorders.
Adrenocortocosteriods
NSAIDS
Vasoconstrictors
Calcium Channel Blockers
Adrenocortocosteroids are secreted by
adrenal cortex
adrenal medulla
Adrenocorticosteroids are divided into 2 major groups- glucocorticoids, and mineralocorticoids. The major glucocorticoid present in the body is cortisol.
True True
True False
False True
False False
Without stress, the normal adult secretes approx. 20mg of hydrocortisone daily.
True
False
The maximal secretion of cortisol occurs between __am and ___am in people with a normal sleep schedule.
4, 8
2, 4
4, 6
2, 6
A disease produced by a deficiency of adrenocorticosteroids.
Graves
Addisons
Cushing
Steven Johnsons
A disease caused by EXCESS of adrenocorticosteroids.
Cushing
Addisons
Graves
Sjorgens
Corticosteroids are palliative rather than curative.
True
False
Adrenocorticosteroids may mask symptoms of an infection.
True
False
Corticosteroids can increase intraocular pressure, which may exaberate glaucoma.
True
False
With a patient with dental phobia, there is risk for adrenal crisis due to a relative lack of corticosteroids during stress.
true
false
The most common oral corticosteroid.
Prednisone
Triamcinolone Acetonide
Methylprednisone
Because steroids can delay wound healing, patients receiving long term oral steroids may require antibiotic prophylaxis prior to dental appointments.
True
False
Patients currently taking _____mg of Hydrocortisone daily should be prescribed supplemental corticosteroids BEFORE a stressful dental procedure.
10-20
20-40
40-50
50-60
The dental paste form of betamethasone is mostly used to treat
aphthous ulcers
dry socket
irritation fibroma
During an allergic reaction, mast cells degranulate and histamine is released.
True
False
The predominant feature of anaphylaxis is
Bronchoconstriction
Bronchodialation
What is the drug of choice for anaphylaxis?
Epinephrine
Antihistamines
Aspirin
NSAIDS
The most common side effect for antihistamines
Sedation
GI tract
Nausea
Itchiness
Benadryl is suggested as an alternative agent to provide LA when a patient has exhibited ALLERGIES to the normally used anesthetic agents.
True
False
Anticholinergic effects lead to __________, which can cause numerous dental problems
Gingival hyperplasia
Xerostomia
Acidity in saliva
Peripheral H1 Receptor agents cross the blood brain barrier.
True
False
Intranasal decongestants should not be used more than _______ consecutive days in order to avoid rebound congestion.
3-5
2-4
1-2
5-7
Psychiatric disorders include
Psychoses
Affective Disorder
Neuroses
Bi-Polar
Schizophrenia
First generation antipsychotic drugs are active against the ________ effects of psychosis, but have little effects on the ___________ effects.
Negative, positive
Positive, negative
Positive symptoms include
Agitation
Delusions
Auditory hallucinations
Distorted speech
Social withdrawal
Patient who exhibit alternating periods of depression and excitation
Bipolar
Schizophrenia
Anxiety
Bipolar disorder is treated with
Lithium
Antidepressants
Antipsychotics
First generation agents are more commonly used vs second generation, because they have effects against the positive and negative effects associated with psychosis.
True
False
The lower the potency of antipsychotic, the more sedation, peripheral side effects, and autonomic effects.
True
False
Typically in women over 40, who have been taking LARGE doses of Phenothiazine for a minimum of 6mo-20 years. The onset is GRADUAL and symptoms are EXACERBATED on drug withdrawal.
Tardive Dyskinea
Parkinsons
Akathisia
Patients taking antipsychotic agents experiencing TMJ pain, should be counteracted by giving which type of drug?
Anticholinergics
NSAIDS
Aspirin
Acyclovir
Patients on first generation antipsychotics CANNOT take smoking cessation meds like BUPROPION (Zyban) due to an increased risk of
Heart failure
Seizure
Stroke
In the case of suicidal thoughts, which would work faster and is safer in a depressed patient?
Antidepressants
ECT (Electroconvulsive therapy)
An adverse reaction to Tricyclic antidepressants is SLUD.
True
False
Which of the following drugs carries a Black Box warning regarding its potential to cause life-threatening LIVER FAILURE
Bupropion (Zyban)
Nefazodone (Serzone)
It is safe to give local anesthetic to clients taking tricyclic antidepressants.
True
False
True, but only the cardiac dose
Lithium is used more often than Valproate in the treatment of BIPOLAR due to its more tolerable side effects.
True
False
Generalized seizures include Absence (petit mal), Tonic-clonic (grand-mal, most common). Neither petit mal nor grand mal seizures is preceded by a true aura.
True True
True False
False True
False False
Drug of choice for status epilepticus
Diazepam (Valium)
Ethosuximide
Phenobarbital
Anti epileptics are CNS depressants. Exact mechanism of action is unknown.
True
False
Anti epileptic agents have a _________ TI.
High
Low
Idiosyncratic reactions such as Drug induced ___________, are an adverse reaction of anti epileptic drugs.
Systemic Lupus Erythematosus
Sjorgen Syndrome
Steven Johnsons Syndrome
Cushing Disease
Carbamazepine (Tegretol) is used in dentistry in the treatment of trigeminal neuralgia. The dental team should observe the oral cavity for petechiae or signs of infections in patients taking this medication.
True
False
Persons with untreated CVD are at an increased risk for severe perio disease, insulin-dependant diabetes, atherosclerosis, and emboli production.
True
False
Which side of the heart typically fails first?
Left
Right
Left side heart failure, semi supine. Right side heart failure, supine.
True
False
Most common drug used for heart failure (also used for arrhythmias), and have a narrow therapeutic index.
Digoxin (Lanoxin)
Diuretics
Nitroglycerin
Nifedipine
In a normally functioning heart, the bundle of HIS receives its electrical input from the
AV Node
SA node
Most commonly used fro ACUTE anginal episodes
Nitroglycerin
Digoxin
Calcium Channel Blockers
Prophylactic nitrates should be given with an 8-12 hour "vacation" every day (often during sleep)
True
False
Nifedipine is associated with gingival enlargement and dysgeusia.
True
False
Hypotension is the most common cardiovascular disease.
true
false
Works by promoting excretion of sodium and water, which in turn lowers blood volume and pressure.
Thiazide
Loop diruretics
Potassium Sparing diuretics
Most important dental drug interaction with thiazides is with
NSAIDS
Aspirin
Warfarin
Adrenocoticosteroids
Primarily used to treat hypertension and edema, and example is Lasix
Loop diuretics
Thiazide
Potassium sparing
Suffix of ACEIs
-pam
-pril
-lam
-ine
ACEIs retard the progression of diabetic nephropathy whether hypertension is present or not.
True
False
ACEIs are safe to administer to pregnant women
True
False
Angiotensin Receptor Blockers (ARBs) suffix
-pril
-artan
-lam
-ine
CCBs suffix (Calcium Channel Blockers)
-artan
-pril
-dipine
Mechanism of calcium channel blockers
vasodilation
vasoconstriction
NSAIDS are safe to use with calcium channel blockers
True
False
Propranolol blocks both B1 & B2 receptors, which can worsen ___________
Asthma
Seizures
Diabetes
_________ works by inhibiting the secretion of very low density lipoproteins without accumulation of triglycerides in the liver
Niacin
Lovastatin
Hydralzine
CCBs
Warfarin antagonizes vitamin
D
E
K
A
Most dental procedures require a change in the dose of warfarin
True
False
