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MODULE 2 PCOG PINK 201 - 300

Total questions: 100

Worksheet time: 50mins

Name
Class
Date
1.
The alkali-catalyzed hydrolysis of fats and fixed oils is known as:
a)
Esterification
b)
Saponification
c)
Oxidation
d)
Lipolysis
2.
The basic nitrogenous compound present in lecithin:
a)
Adenosine
b)
Guanine
c)
Choline
d)
Acetylcholine
3.
The number of milligrams of potassium hydroxide required to neutralize the free acids in 1 grams of sample:
a)
Iodine value
b)
Saponification value
c)
Acid value
d)
Ester value
4.

Which of the following statements regarding fixed oils is true?

a)

a. Fixed oils are classified into drying and non-drying oils

b)

b. When exposed to air, non-drying oils undergo oxidation with formation of tough, hard film.

c)

c. The drying quality is caused by the presence of unsaturated fatty acids of a distinctive character, such as linoleic and linolenic acids.

d)

A and B

e)

A and C

5.

Which of the following pairs is correct?

a)

a. Castor- antirachitic

b)

b. Olive Oil- Emollient

c)

c. Lecithins- pharmaceutic aid for emulsions

d)

A and B

e)

B and C

6.
Which of the following is true regarding volatile oils?
a)
Volatile oils or essential oils are called olea aetherea in some countries.
b)
The solid portion that separates upon standing of the volatile oils is called eleoptene.
c)
The liquid portion that separates is called stearoptene.
d)
All of the above
7.

Example(s) of commercial stearoptenes.

a)

a. Thymol

b)

b. Camphor

c)

c. Menthol

d)

All of the above

e)

A and B

8.
Use of castor oil:
a)
Retardant for dental cement
b)
Anti-diarrheal
c)
Stimulant cathartic
d)
Emulsifying agent
9.
These are esters resulting from the condensation of high molecular weight, straight chain fatty chains fatty acids and high molecular weight, primary, straight chain alcohols:
a)
Terpenes
b)
Steroids
c)
Volatile oils
d)
Waxes
10.
Function of steroids 1. Molting of insects 2. Development of the reproductive system 3. Induction of sexual reproduction in fungi 4. Pigmentation
a)
3 only
b)
1 and 2
c)
1, 2 and 3
d)
1, 2 and 4
11.
The precursor of the biosynthesis of steroids.
a)
Proline
b)
Isoprene
c)
Squalene
d)
Malonyl-CoA
12.
This is the animal source of Premarin®, which is an example of conjugated estrogen.
a)
Frog
b)
Rabbit
c)
Dog
d)
mare
13.
This is the principal glucocorticoid substance of the adrenal cortex.
a)
Cortisone
b)
Cortisol
c)
Desoxycorticosterone
d)
Desoxycortone
14.
Steroidal hormones are bound to:
a)
Lipids
b)
Carbohydrates
c)
Albumin
d)
Blood
15.
Animal employed in the assay of digitalis glycosides.
a)
Dog
b)
Cat
c)
Pigeon
d)
Rabbit
16.
Animal employed in the assay of heparin.
a)
Rachitic cat
b)
Dog
c)
Cat
d)
Sheep
17.
Animal employed in the assay of insulin
a)
Dog
b)
Cat
c)
Pigeon
d)
Rabbit
18.
It is the most lipid-soluble of the cardiac glycoside used in therapeutics.
a)
Deslanoside
b)
Digitoxin
c)
Digoxin
d)
Digitalis
19.
The oil obtained from a variety of rapeseed.
a)
Benne oil
b)
Flaxseed oil
c)
Canola oil
d)
Persic oil
20.
Water content of anhydrous lanolin.
a)
0.0025
b)
0.005
c)
0.001
d)
0.01
21.
Prostaglandin that is used orally in patients that are high risk for developing ulcers during NSAID therapy, which is banned in some countries due to its abortifacient property.
a)
Alprostadil
b)
Carboprost
c)
Dinopostone
d)
Misoprostol
22.
The waxy substance derived from the head of sperm whale, Physeter macrocephalus.
a)
Carnauba
b)
Ambergis
c)
Spermaceti
d)
Civet
23.
The most important dietary precursor of the prostaglandins is
a)
Linoleic acid
b)
Linolenic acid
c)
Arachidonic acid
d)
Palmitoleic acid
24.
Peanut oil is also known as
a)
Rapeseed oil
b)
Arachis oil
c)
Olive oil
d)
Teel oil
25.
The toxic lectin principle of Ricinus communis.
a)
Ricinine
b)
Ricitin
c)
Ricin
d)
Hemagglutinin
26.
These are esters resulting from the condensation of high molecular weight, straight chain fatty acids and high molecular weight, primary straight chain alcohols.
a)
Terpenes
b)
Steroids
c)
Volatile oils
d)
Waxes
27.
A fatty acid prepared from the pyrolysis of ricinoleic acid that has antifungal property.
a)
Stearic acid
b)
Undecylenic acid
c)
Linolenic acid
d)
Oleic acid
28.
This is obtained from the lipid fraction of Glycine soja, that can be used as a precursor of steroidal hormones.
a)
Cholesterol
b)
Ergosterol
c)
Stigmasterol
d)
Cholecalciferol
29.
This is the powdered mare after the cacao butter is expressed.
a)
Bitter chocolate
b)
Sweet chocolate
c)
Breakfast cocoa
d)
Cocoa shell powder
30.
Jojoba oil, a liquid wax expressed from the seeds of Simmondsia chinensis, belongs to the family
a)
Buxaceae
b)
Apiaceae
c)
Arecacea
d)
Asteraceae
31.
Hyoscyamine, when racemized during extraction, is converted to
a)
Scopolamine
b)
(-)-tropin
c)
Hyoscine
d)
Atropine
32.
Which of the following statements is/are true regarding alkaloids? 1. Free alkaloids are sparingly soluble in water. 2. Alkaloids combine directly with acids to form salts. 3. Alkaloids are liberated from aqueous solutions of their salts by acids. 4. Alkaloids form highly insoluble precipitates with salts of heavy metals.
a)
3 only
b)
1, 2 and 3
c)
1, 2 and 4
d)
2 only
33.
Broom, Cytisus scoparius (Fam. Fabaceae) contains this alkaloids, which is used for cardiac arrhythmias and as oxytocic.
a)
Lycopsamine
b)
Sparteine
c)
Thebaine
d)
Conline
34.
Which of the following is classified as tropane alkaloid?
a)
Scopolamine
b)
Solanine
c)
Brucine
d)
Cephaeline
35.
Thalleioquine reaction is used to identify this alkaloid.
a)
Atropine
b)
Caffeine
c)
Morphine
d)
Ephedrine
36.
Strychnine and brucine are examples of _________ alkaloids.
a)
Indole
b)
Purine
c)
Imidazole
d)
Tropane
37.
Mescaline, a psychomimetics, is obtained from
a)
Psilocybe mexicana
b)
Lophophora williamsii
c)
Catha edulis
d)
Rivea corymbosa
e)
Hordeum vulgare
38.
This is preferred over caffeine in the treatment of cardiac edema and angina pectoris because it has little stimulant action on the CNS.
a)
Theophylline
b)
Theobromine
c)
Coffee
d)
Aminophylline
e)
Xanthine
39.
Aside from antihypertensive action, reserpine is also officially used as a/an.
a)
Cure of dysentery
b)
Febrifuge
c)
Antidote for snake bite
d)
Adjunct in psychotherapy
e)
Anticancer agent
40.
Atropine, an antidote in poisoning caused by physostigmine and organphosphate insecticides, is an example of ________ alkaloids.
a)
Tropane
b)
Indole
c)
Flavonoid
d)
Purine
41.
A skeletal muscle relaxant from South American Arrow poison
a)
Tubocurarine chloride
b)
Atracurium besylate
c)
Physostigmine
d)
Sanguinarine
e)
Berberine
42.
Which of the following alkaloids exist as a liquid?
a)
Coniine
b)
Lobeline
c)
Atropine
d)
Quinine
e)
Tubocurarine
43.
The official test animal used to assay curare alkaloids by the “head drop” cross-over method.
a)
Cat
b)
Dog
c)
Pigeon
d)
Mice
44.
Thorn apple, which yields scopolamine, is called locally as
a)
Talong
b)
Tambalisa
c)
Trompeta
d)
Talampunay
e)
Tangan-tangan
45.
Alkaloid reagents are used to precipitate alkaloids. Which alkaloidal reagent is composed of phosphotungstic acid?
a)
Wagner’s reagent
b)
Scheilbler’s reagent
c)
Mayer’s reagent
d)
Sonneschein reagent
46.
Paracelsus referred to it as the “stone of immortality”.
a)
Morphine
b)
Codeine
c)
Heroin
d)
Opium
e)
Cocaine
47.
Vinblastine exerts its antineoplastic action by
a)
Interfering with DNA coding and replication
b)
Preventing the conversion of folinate to tetrahydrofolate
c)
Inhibitng DNA gyrase
d)
Interfering with the polymerization of tubulin into microtubules.
e)
Modulating the immune system
48.
This substance, which was discovered by A. Hoffman is considered as the most and most specific hallucinogen known
a)
Mescaline
b)
Lysergic acid diethylamide
c)
Methysergide
d)
Ergine
e)
Lysergic acid
49.
Caffeine is used with this ergot alkaloid to treat migraine headaches.
a)
Methysergide maleate
b)
Ergotamine tartrate
c)
Methylergonovine maleate
d)
Ergometrine maleate
50.
Serpasil® is a prescription product of which alkaloids?
a)
Codeine
b)
Caffeine
c)
Reserpine
d)
Ergometrine
e)
Physostigmine
51.
Nicotine, an alkaloid from Nicotiana tabacum, is a derivative of
a)
Piperidine
b)
Nicotinic acid
c)
Pyrrolidine
d)
Tropane
e)
Tropine
52.
This alkaloid contains an indole nucleus
a)
Pilicarpine
b)
Ephedrine
c)
Reserpine
d)
Caffeine
e)
Atropine
53.
This assay provides information about the percent of extractive representing the total class of plant alkaloid.
a)
Proximate assay
b)
Ultimate assay
c)
Spectrometric assay
d)
Chromatographic assay
e)
Titrimetry
54.
The chief source of hyoscine
a)
Atropa belladonna
b)
Daatura fastuosa
c)
Hyoscyamus niger
d)
Datura stramonium
e)
Hyoscyamus muticus
55.
This alkaloid is employed in ophthalmology to treat glaucoma.
a)
Emetine
b)
Eserine
c)
Morphine
d)
Reserpine
e)
Strychnine
56.
An ipecac preparation, which is a component of poison antidote kits
a)
Ipecac fluidextract
b)
Dover’s powder
c)
Ipecac syrup
d)
Emetine HCl
e)
Powdered ipecac
57.
This alkaloidal reagent is composed of mercuric potassium iodide.
a)
Mayer’s reagent
b)
Marme’s reagent
c)
Wagner’s reagent
d)
Dragendorff’s reagent
58.
Basic nitrogenous compounds of plant origin that are physiologically active
a)
Glycosides
b)
Alkaloids
c)
Hormones
d)
Terpenoids
e)
Lipids
59.
Which of the following local plants yields an alkaloid of the pyridine-piperidine type?
a)
Ambal
b)
Anonas
c)
Chichirica
d)
Dapdap
e)
Ipil-ipil
60.
Which of the following alkaloidal reagents is composed of iodine in potassium iodide?
a)
Wagner’s reagent
b)
Mayer’s reagent
c)
Dragendorff’s reagent
d)
Phosphotungstic acid
61.
Which of the following pairs are correct?
a)
Physostigmine- mydriatic
b)
Morphine- analgesic
c)
Brucine- central depressant
d)
Atropine- miotic
62.
Which of the following alkaloids is classified as an anthelmintic in veterinary practice?
a)
Lobeline
b)
Nicotine
c)
Arecoline
d)
Scopolamine
63.

Biologics may be classified as

a)

a. Antigen

b)

b. Antibody

c)

c. Antitoxin

d)

A and B

64.
264. Active immunity may be acquired through 1. Recovery from an infection 2. Series of administration 3. Repeated injections of a toxoid
a)
3 only
b)
1 and 2
c)
1 and 3
d)
44199
65.
All biologics are dated or carry an expiration date on their label because
a)
They do not retain their potency for an indefinite period
b)
The activity of a biological product is rapidly lost
c)
The biologic has its own half life
d)
The biologics come from variable sources
66.
The following statements regarding vaccines are true 1. Vaccines are composed of attenuated or live or killed immunity of an individual 2. Vaccines are given primarily to stimulate the passive immunity of an individual 3. Vaccines are used as inoculations to stimulate the productions of antibodies 4. Vaccines may be developed using recombinant technology
a)
3 only
b)
1, 3 and 4
c)
1, 2 and 4
d)
1, 2 and 3
67.
Which of the following statements regarding polio vaccines is TRUE?
a)
Inactivated polio vaccine is commonly called trivalent oral polio vaccine (TOPV).
b)
Inactivated polio vaccine is more commonly referred to as Salk Polio vaccine
c)
Polioviruss vaccine inactivated is more commonly known as Sabin vaccine.
d)
All of the above
68.
Measles vaccine is recommended for active immunization for
a)
Children 15 months of age or older
b)
Infants under 15 months of age
c)
Children 3 year old and older
d)
Children under 10 years of age
69.
Regarding bacterial vaccines, which of the following is TRUE? 1. An oral vaccine for typhoid is available as an enteric-coated capsule 2. Meningococcal vaccines are not efficacious in children under 2 years old 3. Haemophilus B vaccine are used in children less than 18 months of age 4. Pertussis vaccine is usually accompanied by a dose of acetaminophen to reduce the risk of high fever and febrile convulsions.
a)
3 only
b)
1, 3 and 4
c)
1, 2 and 4
d)
1, 2 and 3
70.
Diagnostic antigens are employed to
a)
Protect an individual from a disease
b)
Stimulate passive immunity
c)
Activate active immunity
d)
Determine whether an individual has developed hypersensitivity
71.
What is used to culture measles virus?
a)
Agar
b)
Armadillo
c)
Monkey
d)
Avian embryo tissue
72.
An allergic reaction is primarily due to the release of
a)
Serotonin
b)
Adrenaline
c)
Bradykinin
d)
Histamine
73.
Poison ivy and oak contain a non-volatile phenolic principle producing allergic symptoms. This substance is
a)
Urushiol
b)
Toxicodendrol
c)
3-pentodecylcatechol
d)
Exine
74.
The toxic component in castor bean
a)
Ricinoleic acid
b)
Linoleic acid
c)
Lycorine
d)
Ricin
75.
Examples of bacterial vaccines 1. Cholerea vaccine 2. Plague vaccine 3. Hepa A vaccine 4. TB vaccine
a)
3 only
b)
1 and 2
c)
1, 2 and 3
d)
1, 2 and 4
76.
A two-plus (++) designation of a skin test means:
a)
Wheal with definite pseudopods and erythema
b)
Definite wheal with surrounding erythema
c)
Erythema larger than 20mm but no wheal
d)
Erythema smaller than 20mm in diameter
77.
Weeds associated with pollinosis include members of
a)
Amaranthaceae
b)
Asteraceae
c)
Chenopodiaceae
d)
All of the above
78.
The most common outcome of the ingestion of a toxic plant is
a)
Acute dermatitis
b)
Hepatitis
c)
Nausea, vomiting and diarrhea
d)
Pneumonia
79.
Picrotoxin is a
a)
Narcotic analgesic
b)
Powerful anticonvulsant
c)
Central depressant
d)
Terotogenic
80.
The toxic principle in jequirity beans is
a)
Dauricine
b)
Abrin
c)
Tung oil
d)
Gelsemine
81.

Most poisonous and non-edible mushrooms contain

a)

a. Muscarine

b)

b. Ibotine

c)

c. Amanitine

d)

d. A and B

82.
Which is/are teratogenic poison(s)?
a)
Capsaicin
b)
Coniine
c)
Linamarin
d)
None of the above
83.
Toxic cyanogen found in cassava
a)
Amygdalin
b)
Jacobine
c)
Linamarin
d)
Anabarine
84.
Factors contributing to the variability in the concentration of toxic components in plants may be
a)
Plant part used
b)
Age of plant
c)
Climactic and soil differences
d)
All of the above
85.
Capsaicin, found in different species of capsicum, primarily causes of what organ of the body?
a)
Skin
b)
Lungs
c)
Kidney
d)
eyes
86.
Which of the following is an example of an imidazole alkaloid?
a)
Green and white hellebore
b)
Nicotine
c)
Pilocarpine
d)
Hydrastis
87.
The coffee family belongs to what type of alkaloidal family?
a)
Pyridine-piperidine
b)
Tropane
c)
Quinoline
d)
Purine
88.

Which of the following statements is true regarding decaffeinized coffee?

a)

a. It normally contains 0.08% of caffeine.

b)

b. It normally contains 0.8% of caffeine.

c)

c. It has a higher price than ordinary caffeine.

d)

Both A and C

e)

Both B and C

89.

Which of the following statements regarding pilocarpine is true?

a)

a. It is an imidazole alkaloid

b)

b. Cholinergic drug used in the treatment of glaucoma

c)

c. Mydriatic

d)

All of the above

e)

A and B only

90.
Which of the following statements is correct about gingko?
a)
Contraindicated in diabetes and pregnancy
b)
Has a drug-herb interaction with USA
c)
Toxic effects include hypertension and cardiac arrest
d)
Has a drug-lab interaction with phenelzine
91.
Which of the following ergot alkaloids is a component of Hydergine®?
a)
Ergonovine maleate
b)
Methylergonovine maleate
c)
Ergotamine tartrate
d)
Ergotoxine
92.
Which of the following statements is TRUE regarding ephedrine?
a)
It is a component of a topical OTC preparation
b)
It is a cholinomimetic agent that stimulates alpha and beta receptors.
c)
It is an example of a steroidal alkaloid.
d)
It is an example of a purine base.
93.

Theophylline, prepared from the leaves and leaf buds of Camellia sinensis (Theaceae) is an example of a purine base alkaloid. Which of the following statements is correct?

a)

a. Its astringent property is due to tannin content.

b)

b. It has smooth muscle relaxant property.

c)

c. It causes urinary retention

d)

Only A and B

94.

Which of the following statements is true regarding theobromine?

a)

a. It is known as 1,3-dimethylxanthine

b)

b. It has little stimulant action on the central nervous system

c)

c. It is preferred over caffeine in the treatment of cardiac edema

d)

d. A and B

e)

e. B and C

95.
What do you call the active principle of poison ivy, Toxicondendron species, which may cause dermatitis upon penetration of the epidermis of the skin?
a)
Abrin
b)
Uroshiol
c)
Undecylinic acid
d)
Ursolic acid
96.
The scientific name of lagundi is
a)
Vitex negundo
b)
Momordica charantia
c)
Blumea balsamifera
d)
Artocarpus heterophyllys
97.
The approved therapeutic use of lagundi.
a)
Antidiarrheal
b)
Remedy for asthma and cough relief
c)
Hypoglycemic
d)
Relief of stomachaches
98.
Sambong is used as
a)
Analgesic
b)
Diuretic
c)
Anthelmintic
d)
Stimulant
99.
Which of the following has been linked to high rates or oral and esophageal cancer?
a)
Camellia sinepsis
b)
Quercus infectoria
c)
Areca catechu
d)
Blumea balsimefera
100.
Which of the following is the carcinogenic constituent found in “nganga”?
a)
Tannin
b)
Glycoside
c)
Alkaloid
d)
Volatile Oil