NEW
Font size
WorksheetsPAD NAPLEX Review 3e
Total questions: 12
Worksheet time: 6mins
Clopidogrel works by which of the following mechanisms?
Selectively and irreversibly inhibits ADP-induced platelet aggregation.
Reversibly inhibits platelet aggregation.
Reduces blood viscosity by inhibiting phosphodiesterase.
Suppresses cyclic adenosine monophosphate (cAMP) degradation, which produces vasodilation.
A 42-year-old smoker with hypertension, diabetes, hypercholesterolemia, and PAD complains of pain in his calves when he walks two to three blocks. What therapy might offer him the greatest benefit in symptom reduction and in overall mortality?
Limb revascularization procedure
Cilostazol
Smoking cessation
Pravastatin
A 58-year-old male patient with heart failure, erectile dysfunction, and CAD with stable angina underwent testing for PAD after having findings suggestive of PAD on physical examination at his last primary care office visit. Which of the following diagnostic tests is most appropriate to confirm a PAD diagnosis in this patient?
Fecal occult blood test
Toe-brachial index
Cardiac catheterization
Ankle-brachial index
Which of the following is recommended as an alternative antiplatelet therapy for patients with PAD who do not tolerate aspirin?
Pentoxifylline 400 mg twice daily
Clopidogrel 225 mg daily
Clopidogrel 75 mg daily
Pentoxifylline 400 mg three times daily
Which of the following patients would have a contraindication for receiving cilostazol as treatment for peripheral arterial disease?
A 49-year-old woman with hypertension
A 60-year-old man with a history of benign prostatic hypertrophy
A 48-year-old man with congestive heart failure
A 52-year-old woman with hypothyroidism
Select the primary pharmacologic management for PAD.
Anticoagulants
Antiplatelet agents
Antihypertensive agents
Sympatholytic agents
Which of the following immunizations is recommended for patients with PAD?
Pneumococcal PPSV-23
Pneumococcal PCV-13
Annual influenza vaccine
Zoster vaccine
The 58-year-old male patient with heart failure and CAD was diagnosed with PAD after recent testing. Current medications: carvedilol 25 mg po bid, lisinopril 40 mg po daily, aspirin 81 mg po daily. The patient describes his lower extremity pain as cramping up and down the backs of his legs, worse during busy times at the restaurant and resolves with rest. Which of the following therapies would be the best treatment for his leg symptoms?
Cilostazol 100 mg po twice daily
Structured walking exercise therapy
Pentoxifylline 400 mg po three times daily
Clopidogrel 75 mg po daily
Which of the following medications is contraindicated in patients with hypersensitivity to xanthines?
Aspirin
Plavix
Trental
Pletal
Which of the following antiplatelet agents is not generally used in the treatment of PAD and should be monitored with periodic complete blood count testing related to potential hematologic complications that include agranulocytosis and aplastic anemia?
Aspirin
Simvastatin
Ticlopidine
Dipyridamole plus aspirin
Which of the following medications require dosage reduction when administered with strong CYP3A4 inhibitors?
Aspirin
Cilostazol
Pentoxifylline
Clopidogrel
A 66-year-old female patient with PAD and exertional pain in her lower extremities is currently taking cilostazol, aspirin, atorvastatin, and lisinopril. Which of the following is the most common adverse effect of taking cilostazol and aspirin in combination?
Heart failure hospitalizations
Subtherapeutic effects of cilostazol
Skeletal muscle soreness
Increased bleeding risk
